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Molecular Alarm Clock Wakes Resting Ovules
Study of fruit flies yields discovery of a molecular "alarm clock" that activates resting ovules.
Catching Proteins in the Act
Scientists can now observe light activated processes in proteins through the use of free-electron x-ray lasers.
Proteins Preserve Vital Genetic Data
Research has shown how two key proteins bring about the oragnization of chromosomes and our genome.
Signaling Molecule Regulates Release of the Hunger Hormone Ghrelin
Researchers at UT Southwestern have identified that the blocking release of the hormone ghrelin may mediate low blood sugar effect in children taking beta blockers.
Telomere Replenishment in Real Time
Researchers have visualised the process of telomere attachment to chromosomes through single-molecule imaging.
New Inflammatory Disease Discovered
NIH researchers have discovered a rare and potentially deadly disease - otulipenia - the mostly affects children.
World's Most In-Depth Study to Detect Alzheimer's Disease
A multisite team will see the most thorough and vigorous testing for Alzheimer's ever performed on volunteers.
Zika Proteins Responsible for Microcephaly Identified
Researchers have undertaken the first study to examine Zika infection in human neural stem cells from second-trimester fetuses.
Pinpointing Key Influenza-Fighting Immune Trigger
Immunologists have identified the protein trigger that recognises influenza virus infection in cells and triggers their death.
Uncovering Constructor Proteins
Scientists have discovered a new bacterial cell wall builder that could be a target for antibiotic development.
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Automating ELISAs on Tecan’s Freedom EVO® using Optimiser™ technology from Siloam Biosciences
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Tecan Group Ltd.

ELISAs are considered one of the most useful secondary or tertiary type assays in drug discovery, because they elucidate specific cellular pathways and associated mechanisms of action for target genes, proteins or small molecules. They are equally important to clinical biology laboratories, as they enable determination of biomarker concentrations in unknown biological samples.  

There have been a number of attempts to replace the traditional plate-based ELISA with microfluidic-based technology, but in general these have all suffered from the need for specialized liquid handling systems. Until now, microfluidic technology has not been adapted to the SBS plate footprint, and could not make use of the plate-based liquid handling and detection instrumentation found in many life science laboratories. 


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