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New Autism Blood Biomarker Identified
Researchers at UT Southwestern Medical Center have identified a blood biomarker that may aid in earlier diagnosis of children with autism spectrum disorder, or ASD.
FNIH Launches Project to Evaluate Biomarkers in Cancer Patients
Company has announced that it has launched a new project to evaluate the effectiveness of liquid biopsies as biomarkers in colorectal cancer patients.
HIV Particles Used to Trap Intact Mammalian Protein Complexes
Belgian scientists from VIB and UGent developed Virotrap, a viral particle sorting approach for purifying protein complexes under native conditions.
Potential “Good Fat” Biomarker
New method to measure the activity of energy consuming brown fat cells could ease the testing weight loss drugs.
Computational Model Finds New Protein-Protein Interactions
Researchers at University of Pittsburgh have discovered 500 new protein-protein interactions (PPIs) associated with genes linked to schizophrenia.
New Insights into Gene Regulation
Researchers have solved the three-dimensional structure of a gene repression complex that is known to play a role in cancer.
Controlling RNA in Living Cells
Modular, programmable proteins can be used to track or manipulate gene expression.
Soy Shows Promise as Natural Anti-Microbial Agent
Soy isoflavones and peptides may inhibit the growth of microbial pathogens that cause food-borne illnesses, according to a new study from University of Guelph researchers.
Potential Target for Revolutionary Antibiotics
An international team of including the Lomonosov Moscow State University researchers discovered which enzyme enables Escherichia coli bacterium (E. coli) to breathe.
DNA Barcodes Gone Wild
A team of researchers at University of Toronto’s Donnelly Centre and Sinai Health System’s Lunenfeld-Tanenbaum Research Institute (LTRI) has developed a new technology that can stitch together DNA barcodes inside a cell to simultaneously search amongst millions of protein pairs for protein interactions.
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Novel ProteoPrep® 20 Immunoaffinity Depletion Resin for Human Plasma
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Sigma Aldrich

The study of the human plasma proteome is an area of hugeimportance, especially for the pharmaceutical potential ofidentifying disease biomarkers. Many proteins of interestappear at low concentrations in the plasma and are, therefore,difficult to detect.

Identification of potential biomarkers is especially difficult dueto the presence of higher abundance proteins. To addressthese issues, an affinity resin has been developed for removalof 20 high abundance proteins from 8 µl of plasma. Depletionof these abundant proteins allows for visualization of proteinsthat co-migrate with, and are masked by, the high abundanceproteins during 1-D or 2-D gel electrophoresis andHPLC separations. Plasma proteins can then be loaded ontogels, IPG strips, or HPLC columns at higher levels for improvedvisualization/detection of low copy number proteins.

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