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Scientific News
Epigenetic Study Bolsters Alzheimer's Understanding
The current study found that chemical modifications to DNA within the ANK1 gene are strongly associated with measures of neuropathology in the brain.
Identification of Psoriatic Arthritis Mediators in Synovial Fluid
This study represents the most comprehensive proteomic analysis of psoriatic arthritis synovial fluid, to date.
GTEx Project to Expand Functional Studies of Genomic Variation
Larger set of human tissues to be analyzed to contribute to a database and tissue bank that researchers can use to study how genomic variants influence gene activity.
Subcellular Imaging Visualizes Structures of Brain Receptors
The advance opens a new window to study protein interactions in cell membranes in exquisite detail.
UTSW Cancer Researchers Identify Irreversible Inhibitor for KRAS Gene Mutation
Irreversible inhibitor for KRAS gene mutation involved in lung, colon, and pancreatic cancers.
UK Government Must Do More to Reduce Risk of vCJD Infection
Report recommends that UK Government commission a full assessment of the risks currently faced by the UK blood supply.
Capturing Cancer: A Powerful New Technique for Early Diagnosis
Researchers describe an innovative technique for early disease detection, which they call immunosignaturing.
Significant Step Towards Blood Test for Alzheimer's
Scientists have identified a set of 10 proteins in the blood which can predict the onset of Alzheimer’s, marking a significant step towards developing a blood test for the disease.
Researchers Identify Urgent Need for Alzheimer's Disease Drug Development
Analysis of clinical trials published in the journal Alzheimer's Research & Therapy shows that the pipeline for potential treatments of AD is small and rate of success is limited.
New Tool to Study Critical Protein Interaction in Cancer Research
A*STAR scientists used fluorescent molecular rotors to study protein-protein interactions involving p53 and MDM2 in cells.
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The Development of Stapled Peptides that Modulate the BRCA2-RAD51 Interaction
Chiara Valenzano, University of Cambridge, speaking at Discovery Chemistry Congress 2013.

Inhibition of Protein-protein Interactions Using Designed Molecules
Andrew Wilson, University of Leeds, speaking at Discovery Chemistry Congress 2013.

Druggability of Dynamic Protein-Protein Interfaces
Volkhard Helms, Universitat des Saarlandes, speaking at Discovery Chemistry Congress 2013.

Library Design for Tackling Protein-protein Interactions: The 2P2I Approach
Dr Philippe Roche, CNRS, speaking at Discovery Chemistry Congress 2013.

PASylation: the Biological Alternative to PEGylation
Uli Binder, XL Protein GmbH, speaking at Discovery Chemistry Congress 2013.

Approaches to the Discovery of Small-molecule MDM2-p53 Inhibitors
Dr Ian Hardcastle, Newcastle University, speaking at Discovery Chemistry Congress 2013.

Computational Approaches forThe Discovery of Small Molecule Protein-Protein Interaction Inhibitors
Dr Arnout Voet, RIKEN, speaking at Discovery Chemistry Congress 2013.

Microelectronics Meets Microfluidics: Hybrid Integration of Sensors in Microfluidic Devices
Holger Becker, Microfluidic ChipShop GmbH, speaking at Lab-on-a-Chip World Congress 2012

Chemical Biology Approaches to Target Protein Modification in Disease
Megan Wright, Imperial College London, speaking at Discovery Chemistry Congress 2013.

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