Corporate Banner
Satellite Banner
Scientific Community
Become a Member | Sign in
Home>Events>This Event
  Events - November 2012

Introduction to Photostability

23 Nov 2012 - 23 Nov 2012 - Islington, London,

Bookmark and Share

Course objectives
All PharmaTraining courses focus on two key objectives. These are to provide attendees with knowledge - information, which will assist you in making better judgements - and skills, which will allow you to apply the knowledge you have received. We guarantee to engage your interest and commitment on the course, and we expect our training to improve your effectiveness.

About this course
The purpose of this course is to give an overview of photostability,and where it fits in the stability testing programme and the importance of photostability. The course is highly interactive and held in a relaxed environment.

It will cover:
. Why do we do photostability tests?
. Concepts and background in photostability
. Identifying drug substances most likely to absorb light and display signs of poor photostability
. Understanding photostability terminology
. Where does phototstability fit in the overall stability testing program?
. Why does photostability matter? (exercise)

Who will benefit: The course is designed for people working in:
. Analytical Development
. Analytical Chemistry
. Stability Testing

Course Programme
Coffee and registration will be available from 8.30am, course proper will commence at 9.00am. We anticipate the course will finish at 5.00pm.

Formulating and manufacturing unstable products
. Formulation development and evaluation for photolabile materials
. Protection during the manufacturing process
. Getting the product to the patient

ICH guidelines for photostability testing: Using ICH Q1B guidance in practice
. understanding the terms and procedures used in the guideline

. Light source selection - Options 1 and 2
. Sample presentation
. Humidity and temperature control
. Selecting sample containers

Forced degradation: Practical and regulatory aspects of photostability
stress testing
. Selecting experimental conditions for stressing samples with respect to light
Meeting regulatory requirements
. Documentation – principles and practice
. Stability testing and the Quality System
. SOPs for stability testing
. Equipment validation and calibration – do the chambers work?
. Protocol development and approval
Reporting stability test data
Delegate Workshop
Problems and issues for discussion

Additional Resources
Online access to comprehensive publications including all relevant guidance will be provided as well as colour copies of all presentations and case studies.
. Technical Operations
. Research and Development Chemistry
. Formulation Development
. Pharmaceutical & Biopharmaceutical Manufacturing/Production
. Product Development
. Regulatory Affairs
. GLP/GMP Compliance

Dr Michael Gamlen is Managing Director of Pharmaceutical Development Services Ltd, a pharmaceutical consultancy based in Nottingham (UK). Dr Gamlen has over 30 years experience of product stability testing. Awarded a First Class Honours degree in Pharmacy, specialising in Pharmaceutical Engineering, he studied for a PhD at Nottingham University. He was Head of Tablet Development at the The Wellcome Foundation for 15 years, and worked as an outsourcing manager before starting his consultancy business in 2000. Dr Gamlen specialises in managing product development, formulation, tablet and process development studies. He has been teaching professional tabletting courses for many years and his courses are highly rated, exceeding the expectation of the participants in many cases.

Michael continually updates the content of his courses with the latest guidance and extracts of up-to-the minute scientific papers. He provides a substantial body of relevant literature to all course participants as well as copies of all notes and guidance used and a workbook. He is a popular and highly respected presenter.

Further information
Scientific News
New Class of RNA Tumor Suppressors Identified
Two short, “housekeeping” RNA molecules block cancer growth by binding to an important cancer-associated protein called KRAS. More than a quarter of all human cancers are missing these RNAs.
Mathematical Model Forecasts the Path of Breast Cancer
Chances of survival depend on which organs breast cancer tumors colonize first.
Exploring the Causes of Cancer
Queen's research to understand the regulation of a cell surface protein involved in cancer.
Nanocarriers May Carry New Hope for Brain Cancer Therapy
Berkeley lab researchers develop nanoparticles that can carry therapeutics across the brain blood barrier.
RNA-Based Drugs Give More Control Over Gene Editing
CRISPR/Cas9 gene editing technique can be transiently activated and inactivated using RNA-based drugs, giving researchers more precise control in correcting and inactivating genes.
University of Glasgow Researchers Make An Impact in 60 Seconds
Early-career researchers were invited to submit an engaging, dynamic and compelling 60 second video illuminating an aspect of their research.
Metabolic Profiles Distinguish Early Stage Ovarian Cancer with Unprecedented Accuracy
Studying blood serum compounds of different molecular weights has led scientists to a set of biomarkers that may enable development of a highly accurate screening test for early-stage ovarian cancer.
Dead Bacteria to Kill Colorectal Cancer
Scientists from Nanyang Technological University (NTU Singapore) have successfully used dead bacteria to kill colorectal cancer cells.
CRISPR-Cas9 Gene Editing: Check Three Times, Cut Once
Two new studies from UC Berkeley should give scientists who use CRISPR-Cas9 for genome engineering greater confidence that they won’t inadvertently edit the wrong DNA.
Genetically Engineering Algae to Kill Cancer Cells
New interdisciplinary research has revealed the frontline role tiny algae could play in the battle against cancer, through the innovative use of nanotechnology.
Scroll Up
Scroll Down

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,800+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,000+ scientific videos