Corporate Banner
Satellite Banner
RNAi
Scientific Community
 
Become a Member | Sign in
Home>Events>This Event
  Events - December 2013


Biological Interpretation of Next-Generation Sequencing Data

02 Dec 2013 - 06 Dec 2013 - EMBL-EBI,Hinxton, Cambridge, UK



Bookmark and Share


Overview

The course covers analysis of NGS data. Using ChIP-Seq and RNA-Seq datasets as an example, the course will provide ideas and practical advice for the interpretation of NGS data sets in a genomic context.

Topics will include: RNA-Seq and ChIP-Seq data handling, quality assessment and visualisation; region identification and differential expression; data integration and external databases (ENCODE); statistical analysis using R/bioconductor.

What will I learn?

Lectures will give insight into how biological knowledge can be generated from NGS data and illustrate different ways of analysing and integrating such data. Practicals will consist of computer exercises that will enable the participants to apply statistical methods to the analysis of NGS data under the guidance of the lecturers and teaching assistants.

Familiarity with the technology and biological use cases of NGS is required, as is prior experience with standard RNA-Seq and/or ChIP-Seq workflows. Knowledge of R/Bioconductor and the Unix/Linux operating system are also required.

Is it right for me?

This course is aimed at advanced PhD students and post-doctoral researchers who are already applying next generation sequencing (NGS) technologies and bioinformatics methods in their research.

The aim of this course is to familiarise the participants with advanced data analysis methodologies for the interpretation and integration of data derived from different NGS applications including RNA-seq, ChIP-seq, DNA-methylation sequencing, genome-wide association studies (GWAS) and DNA variant detection.



Further information
Scientific News
Liquid Biopsies: Miracle Diagnostic or Next New Fad?
Thanks to the development of highly specific gene-amplification and sequencing technologies liquid biopsies access more biomarkers relevant to more cancers than ever before.
Colon Cancer Blocked in Mice
Case Western Reserve University Researchers block common type of colon cancer tumour in mice, laying groundwork for human clinical trial.
Protein Nanocages Could Improve Drug Design and Delivery
HHMI scientists have designed and built 10 large protein icosahedra that are similar to viral capsids that carry viral DNA.
Discovered Through ‘Big Data’ Analysis
Researchers at the SBP have identified over 100 new genetic regions that affect the immune response to cancer.
New Therapeutic Targets For Small Cell Lung Cancer Identified
Researchers at UTSW Medical Center have identified a protein termed ASCL1 that is essential to the development of small cell lung cancer and that, when deleted in the lungs of mice, prevents the cancer from forming.
Liquid Biopsies Treating Ovarian Cancer
Researchers have discovered a promising monitor and treat recurrence of ovarian cancer. Detecting cancer long before tumours reappear.
Virus Inspired Cell Cargo Ships
Virus-inspired container design may lead to cell cargo ships following construction of ten large, two-component, icosahedral protein complexes.
Uncovering a New Principle in Chemotherapy Resistance in Breast Cancer
The NIH study has revealed an entirely unexpected process for acquiring drug resistance that bypasses the need to re-establish DNA damage repair in breast cancers that have mutant BRCA1 or BRCA2 genes.
Understanding Treatment Resistant Melanoma
Researchers have determined how advanced melanoma becomes resistant; a development toward developing treatments.
Liquid Biopsies: DNA Size Matters
Study finds circulating tumour DNA can be distinguished from healthy DNA through fragment size identification.
Scroll Up
Scroll Down
SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,300+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,800+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!