Corporate Banner
Satellite Banner
Scientific Community
Become a Member | Sign in
Home>News>This Article

BioChemics Awarded Patent for Development of Bifunctional Synthetic Molecules

Published: Thursday, January 31, 2013
Last Updated: Thursday, January 31, 2013
Bookmark and Share
A novel drug delivery and efficacy enhancement technology.

BioChemics announced today that it has received a patent for a new breakthrough drug delivery technology. This technology called Bifunctional Synthetic Molecule, or BSM, involves covalently bonding two existing different molecules together to create a unique, new and chemically-stable molecule which contains desired physicochemical properties for the purpose of enhanced dermal, or other tissue, penetration. BSM also provides co-localization of the different components of the new molecule in the target tissue at the same time, further enhancing efficacy of the drug.

These new molecules allow BioChemics to create new chemical entities (NCE’s) with bifunctional characteristics that are, in some examples, designed to have superior tissue penetration properties and tissue targeting properties. In other examples, the BSM is designed to have a covalent bond that is both tissue-specific and enzyme-labile that releases the different functionalities of the BSM once it is deposited at the target tissue. The multiple functionalities, impacting the target tissue simultaneously, boosts efficacy and enhances disease therapy. We believe that this technology gives BioChemics the potential to re-engineer many existing drugs creating new classes of pharmaceutical agents that have an enhanced efficacy, enhanced pharmacology, and improved safety profiles. The BSM technology is designed to enhance the delivery of drugs and to improve the therapeutic index of the drug by promoting the optimal tissue distribution for maximum therapeutic impact.

“I am excited that we have been awarded this new technology,” said John Masiz, President of BioChemics Inc. “This technology may allow us to create ‘smart drugs’ that have the ability to find the specific diseased tissue target in the body and then concentrate the active drug into that specific tissue for a better therapeutic event. Further, this technology may minimize side effects since non-targeted tissue will not be impacted. This new system continues to build on BioChemics’ predecessor VALE technology and further confirms that advances in drug delivery will be the major source of pharmaceutical advancement over the next decade.”

Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,800+ scientific posters on ePosters
  • More than 4,000+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Scientific News
New Class of RNA Tumor Suppressors Identified
Two short, “housekeeping” RNA molecules block cancer growth by binding to an important cancer-associated protein called KRAS. More than a quarter of all human cancers are missing these RNAs.
Mathematical Model Forecasts the Path of Breast Cancer
Chances of survival depend on which organs breast cancer tumors colonize first.
Exploring the Causes of Cancer
Queen's research to understand the regulation of a cell surface protein involved in cancer.
Nanocarriers May Carry New Hope for Brain Cancer Therapy
Berkeley lab researchers develop nanoparticles that can carry therapeutics across the brain blood barrier.
RNA-Based Drugs Give More Control Over Gene Editing
CRISPR/Cas9 gene editing technique can be transiently activated and inactivated using RNA-based drugs, giving researchers more precise control in correcting and inactivating genes.
University of Glasgow Researchers Make An Impact in 60 Seconds
Early-career researchers were invited to submit an engaging, dynamic and compelling 60 second video illuminating an aspect of their research.
Metabolic Profiles Distinguish Early Stage Ovarian Cancer with Unprecedented Accuracy
Studying blood serum compounds of different molecular weights has led scientists to a set of biomarkers that may enable development of a highly accurate screening test for early-stage ovarian cancer.
Dead Bacteria to Kill Colorectal Cancer
Scientists from Nanyang Technological University (NTU Singapore) have successfully used dead bacteria to kill colorectal cancer cells.
CRISPR-Cas9 Gene Editing: Check Three Times, Cut Once
Two new studies from UC Berkeley should give scientists who use CRISPR-Cas9 for genome engineering greater confidence that they won’t inadvertently edit the wrong DNA.
Genetically Engineering Algae to Kill Cancer Cells
New interdisciplinary research has revealed the frontline role tiny algae could play in the battle against cancer, through the innovative use of nanotechnology.

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,800+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,000+ scientific videos