Corporate Banner
Satellite Banner
RNAi
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Vegetable Fats Tied to Less Prostate Cancer Spread

Published: Wednesday, June 12, 2013
Last Updated: Wednesday, June 12, 2013
Bookmark and Share
After being diagnosed with prostate cancer, men who eat a diet high in vegetable fats may be less likely to have their disease spread.

Researchers found that replacing some carbohydrates with those healthy fats was also tied to a lower risk of dying from any cause during the study. But the opposite was true for saturated and trans fats often found in meat and processed foods.

"A lot of doctors will simply say, ‘Cut out fat,'" after a prostate cancer diagnosis, said Dr. Stephen Freedland, a urologist at Duke University Medical Center in Durham, North Carolina.

But this study challenges that advice, said Freedland, who wrote a commentary on the findings.
"It actually says, if you eat more fat, albeit the right kind of fat,… you're less likely to die of not only prostate cancer, but really of any cause, which really flies in the face of this ‘low-fat, low-fat, low-fat' mantra that we've been told for decades now," he told Reuters Health.

Researchers tracked 4,577 men who were diagnosed with localized prostate cancer during a large study of health workers beginning in 1986. Those men filled out questionnaires every four years on how often they ate or drank about 130 different types of foods and beverages.

Over the next eight to nine years, 315 men developed lethal prostate cancer - cancer that spread to other parts of the body or killed them - and 1,064 died from any cause.

Men who reported getting the highest proportion of their daily calories from vegetable fat - more than 21 percent - after their diagnosis were about one-third less likely to die during the study than those who ate the least vegetable fat. And they had a borderline lower risk of developing lethal cancer.

On the other hand, men who ate a similar amount of animal fat tended to be more likely to die during follow up, from prostate cancer or anything else, than those who skimped on animal meat.

Erin Richman of the University of California, San Francisco, and her colleagues found that switching 10 percent of daily calories from carbohydrates to vegetable fat was linked to a 29 percent lower risk of lethal prostate cancer and a 26 percent lower chance of dying from any cause.

But replacing 5 percent of those calories with saturated fat, or just 1 percent with trans fat, was tied to a 25 to 30 percent higher risk of death during the study period, according to findings published Monday in JAMA Internal Medicine.

"The benefit was really when you were replacing refined carbohydrates with (things like) olive oil and nuts," Richman told Reuters Health.

She said vegetable fats contain antioxidants and may reduce inflammation in the body, thereby making it harder for cancer to spread.

The American Cancer Society estimates about one in six U.S. men will be diagnosed with prostate cancer during his lifetime, and one in 36 will die of the disease.

Because how animals are fed and how meats are cooked may both affect cancer risks associated with eating animal fats, Freedland said, "It becomes difficult to say, ‘Animals are bad; vegetables are good.' It's not that simple."

He recommends that men with prostate cancer cut out simple sugars and processed foods, as that is one of the easiest ways to get to a healthy weight. But not all fat should go.

Richman agreed.

"I think there's enough established benefit that you're not going to do any harm by adding nuts or olive oil," she said.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,100+ scientific posters on ePosters
  • More than 4,500+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
Early Genetic Changes in Premalignant Colorectal Tissue Identified
Findings point to drivers of early cancer development, targets for cancer prevention therapies.
Scientists Find Evidence That Cancer Can Arise Changes
Researchers at Rockefeller University have found a mutation that affects the proteins that package DNA without changing the DNA itself can cause a rare form of cancer.
Breakthrough Approach to Breast Cancer Treatment
Scripps scientists have designed a drug candidate that decreases growth of breast cancer cells.
A Guide to CRISPR Gene Activation
A comparison of synthetic gene-activating Cas9 proteins can help guide research and development of therapeutic approaches.
Testing Non-Breast/Ovarian Cancer Genes
Researchers have found that expanding gene panel beyond breast/ovarian cancer genes in these patients does not add any clinical benefit. Instead, testing has produced more questions than answers.
Myeloid-Derived Suppressor Cells Play Role in Tumor Growth
Researchers at Baylor College of Medicine have reported a new mechanism that helps cancer cells engage myeloid-derived suppressor cells.
Cancer Cells Coordinate to Form Roving Clusters
Rice University scientists identify ‘smoking gun’ in metastasis of hybrid cells.
Poliovirus Therapy Wins 'Breakthrough' Status
FDA decision will fast-track research on breakthrough Duke brain cancer therapy.
Novel Way to Prevent Deadly Bacterial Infections
Monash scientists may have found a way to stop deadly bacteria from infecting patients. The discovery could lead to a whole new way of treating antibiotic-resistant “superbugs”
New Treatment for Pancreatic Cancer
Researchers at Purdue University have shown how controlling cholesterol metabolism in pancreatic cancer cells reduces metastasis.
SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,100+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,500+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!