Corporate Banner
Satellite Banner
Scientific Community
Become a Member | Sign in
Home>News>This Article

Antisense Pharma Changes Name to Isarna Therapeutics

Published: Monday, September 30, 2013
Last Updated: Monday, September 30, 2013
Bookmark and Share
Development efforts focused on next generation oligonucleotides to treat cancer capitalizing on long-standing experience in TGF-ß.

Antisense Pharma GmbH has changed its name to Isarna Therapeutics GmbH and centralized all of its activities to a single location in Munich, the company announced today at the Sachs 13th Annual Biotech in Europe Investor Forum held in Zurich, Switzerland. The company’s new website is

“The name change to Isarna Therapeutics illustrates our new company dynamics combined with our continued leadership in the TGF-β pathway,” explained Dr. Philippe Calais, CEO of Isarna Therapeutics.  “We are currently extending our pipeline to include next-generation oligonucleotides to treat cancer and expect several key near-term events that highlight this momentum.”

Isarna Therapeutics is committed to rapidly advancing a pipeline of next generation oligonucleotides (NGOs) targeting the various isoforms of TGF-β, a family of cytokine proteins that plays a significant role in cancer’s ability to escape immune system detection and promote tumor growth. Based on its unique deciphering of the TGF-β biology, the company has to date amassed an unmatched expertise in discovery and clinical development of oligonucleotides antagonists of the various TGF-β isoforms.  Much of this knowledge is the result of developing its first-generation compound trabedersen for several cancer indications and up to a Phase III clinical trial. The further development of that compound is focused on a Responder Patient Profiling Program (RPPP), aimed at assessing the genetic profile and responder biomarkers of patients suffering from cancer to establish correlations between tumor biology and response to anti-TGF-β oligonucleotides. This unique proprietary program will allow Isarna Therapeutics to select the right patients who will be best suited for treatment not only by trabedersen but also by any of the next generation of TGF-β inhibitors entering clinical development.

“Our goal as a company is to solidify our strengths in the TGF-β isoform family and remain a lean and focused organization capable of rapidly advancing compounds into mid-stage clinical development,” added Dr. Calais.

Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,800+ scientific posters on ePosters
  • More than 4,000+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Antisense Pharma Receives FDA Orphan Drug Designation for Trabedersen
TGF-ß2 inhibitor has gained market exclusivity in the USA for a third aggressive cancer indication.
Friday, October 05, 2012
Antisense Pharma Presents Trabedersen Phase I/II Complete Data at ASCO
Trabedersen demonstrated excellent safety combined with encouraging survival in patients with advanced pancreatic cancer and malignant melanoma.
Tuesday, June 05, 2012
Antisense Pharma Internationalizes Management Board
Dr. Philippe Calais appointed Chief Executive Officer.
Tuesday, May 15, 2012
Antisense Pharma Completes Round of Financing Worth Approximately 8 Million Euro
Effective July, 2011, Antisense Pharma’s founder and CEO, Dr. Karl-Hermann Schlingensiepen, will now be a member of the supervisory board and will focus on the company’s strategy as a consultant.
Thursday, July 07, 2011
Antisense Pharma’s Trabedersen in Malignant Brain Tumors: Phase IIb Data Published in Neuro-Oncology
Antisense Pharma have announced that their international, randomized and active-controlled Phase IIb study G004-AP 12009, has been published in the official journal of the American Society for Neuro-Oncology (SNO).
Tuesday, November 02, 2010
Scientific News
Exploring the Causes of Cancer
Queen's research to understand the regulation of a cell surface protein involved in cancer.
Nanocarriers May Carry New Hope for Brain Cancer Therapy
Berkeley lab researchers develop nanoparticles that can carry therapeutics across the brain blood barrier.
RNA-Based Drugs Give More Control Over Gene Editing
CRISPR/Cas9 gene editing technique can be transiently activated and inactivated using RNA-based drugs, giving researchers more precise control in correcting and inactivating genes.
University of Glasgow Researchers Make An Impact in 60 Seconds
Early-career researchers were invited to submit an engaging, dynamic and compelling 60 second video illuminating an aspect of their research.
Metabolic Profiles Distinguish Early Stage Ovarian Cancer with Unprecedented Accuracy
Studying blood serum compounds of different molecular weights has led scientists to a set of biomarkers that may enable development of a highly accurate screening test for early-stage ovarian cancer.
Dead Bacteria to Kill Colorectal Cancer
Scientists from Nanyang Technological University (NTU Singapore) have successfully used dead bacteria to kill colorectal cancer cells.
CRISPR-Cas9 Gene Editing: Check Three Times, Cut Once
Two new studies from UC Berkeley should give scientists who use CRISPR-Cas9 for genome engineering greater confidence that they won’t inadvertently edit the wrong DNA.
Genetically Engineering Algae to Kill Cancer Cells
New interdisciplinary research has revealed the frontline role tiny algae could play in the battle against cancer, through the innovative use of nanotechnology.
How to Control Shape, Structure of DNA and RNA
Researchers have used computational modelling to shed light on precisely how charged gold nanoparticles influence the structure of DNA and RNA.
Advancing Genome Editing of Blood Stem Cells
Genome editing techniques for blood stem cells just got better, thanks to a team of researchers at USC and Sangamo BioSciences.

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,800+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,000+ scientific videos