Corporate Banner
Satellite Banner
RNAi
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

EKF Molecular Diagnostics Launches New PointMan™ DNA Enrichment Kits

Published: Thursday, November 14, 2013
Last Updated: Thursday, November 14, 2013
Bookmark and Share
New cancer gene detection technology products introduced at AMP, Stand 125.

EKF Diagnostics has announced that EKF Molecular Diagnostics will launch four new PointMan™ DNA enrichment kits at the Association for Molecular Pathology Annual Meeting (AMP 2013), 14-16th November, Phoenix, AZ.

The new kits for the Research Use Only market, with planned diagnostic registration in Europe in 2014, offer highly specific and ultra-sensitive enrichment of multiple mutations in EGFR, NRAS, KRAS and JAK2 genes associated with a variety of cancers.

As a real-time PCR technology, PointMan provides reliable and extremely sensitive detection of cancer mutations by amplifying the target sequence of interest in a background of wild-type genes.

Using this technology, the enrichment kits are an ideal research tool for understanding biomarker and drug response.

Requiring minimal sample and offering fast, efficient and cost effective enrichment of mutant gene sequences, EKF’s new cancer biomarker kits are listed below:

PointMan™ KRAS codons 12/13/61 DNA Enrichment Kit
The KRAS gene has proven utility in the treatment of colorectal cancer and the addition of codon 61 may confirm broader genetic variation within the KRAS gene.
PointMan™ EGFR DNA Enrichment Kit
The newly extended kit includes the addition of the sensitizing mutations in exons 19 and 21 which have proven utility for EGFR targeted therapies in non-small cell lung cancer.
PointMan™ NRAS DNA Enrichment Kit
Mutations in the NRAS gene are found in approximately 13–25% of all malignant melanomas, occurring frequently in codons 12, 13, and 61.
PointMan™ JAK2 DNA Enrichment Kit
Mutations in the JAK2 gene have been implicated in polycythemia vera, essential thrombocythemia, and myelofibrosis as well as other myeloproliferative disorders.

The new launches follow on from the introduction of the first three PointMan™ DNA enrichment products - BRAF, KRAS, EGFR T790M DNA enrichment kits - in May 2013. The extension of EKF Molecular Diagnostic’s portfolio of DNA enrichment kits further enhances the company’s ability to change current DNA extraction and detection practices and address the fast growing companion diagnostics market.

Andrew Webb, CEO of EKF Molecular Diagnostics, commented, “I’m very pleased to announce the launch of our latest research kits, adding to our growing portfolio of kits for use in finding companion diagnostics for cancer treatments. We look forward to introducing further research kits in 2014 that challenge the lack of sensitivity in current methodologies.”

EKF Molecular has also announced the appointment of Chris Booth as Product Specialist. Joining from Qiagen where he worked in the Technology Transfer team, Chris has also previously worked as a Senior Scientist in Product Development at DxS and a Scientific Officer at Cancer Research UK within the cancer mutation detection service.

Chris will be training and supporting EKF Molecular’s customers in the use of the company’s new cancer gene detection products and their application.


Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,500+ scientific posters on ePosters
  • More than 3,700+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
Microscopic Fish are 3D-Printed to do More Than Swim
Researchers demonstrate a novel method to build microscopic robots with complex shapes and functionalities.
Inciting an Immune Attack on Cancer Cells
A new minimally invasive vaccine that combines cancer cells and immune-enhancing factors could be used clinically to launch a destructive attack on tumors.
Reprogramming Cancer Cells
Researchers on Mayo Clinic’s Florida campus have discovered a way to potentially reprogram cancer cells back to normalcy.
New Strategy for Combating Adenoviruses
Using an animal model they developed, Saint Louis University and Utah State university researchers have identified a strategy that could keep a common group of viruses called adenoviruses from replicating and causing sickness in humans.
Surprising Mechanism Behind Antibiotic-Resistant Bacteria Uncovered
Now, scientists at TSRI have discovered that the important human pathogen Staphylococcus aureus, develops resistance to this drug by “switching on” a previously uncharacterized set of genes.
Fat in the Family?
Study could lead to therapeutics that boost metabolism.
Imaging Software Could Speed Up Breast Cancer Diagnosis
Researchers use high speed optical microscopy of intact breast tissue specimens to analyze breast tissue.
A Metabolic Master Switch Underlying Human Obesity
Researchers find pathway that controls metabolism by prompting fat cells to store or burn fat.
Synthetic DNA Vaccine Against MERS Shows Promise
A novel synthetic DNA vaccine can, for the first time, induce protective immunity against the Middle East Respiratory Syndrome (MERS) coronavirus in animal species.
How Small RNA Helps Form Memories
In a new study, a team of scientists at Scripps Florida has found that a type of genetic material called "microRNA" (miRNA) plays surprisingly different roles in the formation of memory in animal models.
SELECTBIO

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FREE!