Corporate Banner
Satellite Banner
RNAi
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Cell Therapy Company Uses TAP’s Fill-It Automated Cryovial Processing System

Published: Thursday, December 05, 2013
Last Updated: Wednesday, December 04, 2013
Bookmark and Share
To rapidly produce consistent cancer immunotherapy batches and cell banks.

TAP Biosystems has announced that its Fill-It™, automated benchtop vial filling system is being routinely used at an innovative cell therapy company developing novel cancer immunotherapies, to improve processing speed and throughput of large batches of cells in cryovials for use as master cell banks or as cell-based immunotherapies.

Scientists at the company are using Fill-It to produce batches of around 1000 cryovials per run, containing 0.65ml of up to 100 million cell/ml of an immunotherapy product candidate, consisting of two allogeneic cancer cell lines.

Fill-It aseptically processes these temperature-sensitive cells at high throughput, enabling vials to be uncapped, filled and recapped at speed, so they can be put them in the freezer quickly to maintain optimum cell quality.

Stephen Guy, Fill-It Product Manager at TAP, explained: “The company wanted to automate their vial processing as it was taking around one and half hours for a scientist to produce a batch of 1000 vials. As well as the RSI issues associated with uncapping and recapping this number of vials, it was difficult to maintain product consistency across the batch. Using the Fill-It automated system, batches of vials are processed at speed with minimal human interaction. The cells are dispensed using sterile, GMP-certified disposable tubing and the vials get into the freezer quickly. This results in cell numbers being maintained at consistently high quality until the vials are thawed for use.”

Guy added: “We are delighted our Fill-It system is helping such an innovative cell therapy company to ensure their critical cancer cell banks and cancer immunotherapies are maintained in top condition. This firm’s routine application of our technology demonstrates to cell therapy companies looking for a method of rapidly producing large batches of consistent quality cells that a Fill-It system is a tried and trusted choice.”


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,500+ scientific posters on ePosters
  • More than 5,000+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
Fighting Cancer with Sticky Nanoparticles
Treatment that uses bioadhesive nanoparticles drug carriers proved more effective than conventional treatments for certain cancers.
Fighting Plant Pathogens with RNA
Researchers develop strategy that could lead to environmentally friendly fungicide to fight pathogens.
Smart Material Hunts Cancers
Team has created smart material that locates and images cancer or tumour sites in tissue.
Examining mtDNA May Help Identify Unknown Ancestry That Influences Breast Cancer Risk
Researchers studying mtDNA in a group of triple negative breast cancer patients found that 13 percent of participants were unaware of ancestry that could influence their risk of cancer.
Gene Therapy Technique May Help Prevent Cancer Metastasis
Gene-regulating RNA molecules could help treat early-stage breast cancer tumors before they spread.
Enhancing Antibiotics to Defeat Resistant Bacteria
Scientists enhance ability of antibiotics to defeat resistant types of bacteria using molecules called PPMOs
MRI Guidance Aids Stem Cell Delivery
Scientists have delivered stem cells to the brain with unprecedented precision, infusing the cells under real-time MRI guidance.
High-Capacity Nanoparticles
New type of nanoparticle can now have three or more drugs packaged within it, allowing for customised cancer therapy.
UTSW Creates Nanoparticles That Target Lung Cancer Cells
Researchers at UTSW have developed a synthetic polymers that could deliver nucleic acid drugs while possessing enough structural diversity to discover cancer cell-specific nanoparticles.
Delivering Beneficial Bacteria
Method that transports microbes through the stomach to the intestine may benefit human health.
SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,000+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!