Corporate Banner
Satellite Banner
RNAi
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Cell Therapy Company Uses TAP’s Fill-It Automated Cryovial Processing System

Published: Thursday, December 05, 2013
Last Updated: Wednesday, December 04, 2013
Bookmark and Share
To rapidly produce consistent cancer immunotherapy batches and cell banks.

TAP Biosystems has announced that its Fill-It™, automated benchtop vial filling system is being routinely used at an innovative cell therapy company developing novel cancer immunotherapies, to improve processing speed and throughput of large batches of cells in cryovials for use as master cell banks or as cell-based immunotherapies.

Scientists at the company are using Fill-It to produce batches of around 1000 cryovials per run, containing 0.65ml of up to 100 million cell/ml of an immunotherapy product candidate, consisting of two allogeneic cancer cell lines.

Fill-It aseptically processes these temperature-sensitive cells at high throughput, enabling vials to be uncapped, filled and recapped at speed, so they can be put them in the freezer quickly to maintain optimum cell quality.

Stephen Guy, Fill-It Product Manager at TAP, explained: “The company wanted to automate their vial processing as it was taking around one and half hours for a scientist to produce a batch of 1000 vials. As well as the RSI issues associated with uncapping and recapping this number of vials, it was difficult to maintain product consistency across the batch. Using the Fill-It automated system, batches of vials are processed at speed with minimal human interaction. The cells are dispensed using sterile, GMP-certified disposable tubing and the vials get into the freezer quickly. This results in cell numbers being maintained at consistently high quality until the vials are thawed for use.”

Guy added: “We are delighted our Fill-It system is helping such an innovative cell therapy company to ensure their critical cancer cell banks and cancer immunotherapies are maintained in top condition. This firm’s routine application of our technology demonstrates to cell therapy companies looking for a method of rapidly producing large batches of consistent quality cells that a Fill-It system is a tried and trusted choice.”


Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,500+ scientific posters on ePosters
  • More than 3,700+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
Liquid Biopsies: Utilization of Circulating Biomarkers for Minimally Invasive Diagnostics Development
Market Trends in Biofluid-based Liquid Biopsies: Deploying Circulating Biomarkers in the Clinic. Enal Razvi, Ph.D., Managing Director, Select Biosciences, Inc.
Self-Assembling, Biomimetic Membranes May Aid Water Filtration
A synthetic membrane that self assembles and is easily produced may lead to better gas separation, water purification, drug delivery and DNA recognition, according to an international team of researchers.
Error Correction Mechanism in Cell Division
Cell biologists have reported an advance in understanding the workings of an error correction mechanism that helps cells detect and correct mistakes in cell division early enough to prevent chromosome mis-segregation and aneuploidy, that is, having too many or too few chromosomes.
Researchers Resurrect Ancient Viruses
Researchers at Massachusetts Eye and Ear and Schepens Eye Research Institute have reconstructed an ancient virus that is highly effective at delivering gene therapies to the liver, muscle, and retina.
Cell Aging Slowed by Putting Brakes on Noisy Transcription
Experiments in yeast hint at ways to extend life of some human cells.
Crucial for Stem Cell Survival Protein Identified Using Editing Tool CRISPR
A team of University of Wisconsin-Madison engineers has identified a protein that is integral to the survival and self-renewal processes of human pluripotent stem cells (hPSC).
Long Telomeres Associated with Increased Lung Cancer Risk
Genetic predisposition for long telomeres predicts increased lung adenocarcinoma risk.
First Artificial Ribosome Designed
Researchers at the University of Illinois at Chicago and Northwestern University have engineered a tethered ribosome that works nearly as well as the authentic cellular component, or organelle, that produces all the proteins and enzymes within the cell.
Identifying a Key Growth Factor in Cell Proliferation
Researchers discover that aspartate is a limiter of cell proliferation.
A Gene-Sequence Swap Using CRISPR to Cure Haemophilia
For the first time chromosomal defects responsible for hemophilia have been corrected in patient-specific iPSCs using CRISPR-Cas9 nucleases
SELECTBIO

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FREE!