Corporate Banner
Satellite Banner
RNAi
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Cell Therapy Company Uses TAP’s Fill-It Automated Cryovial Processing System

Published: Thursday, December 05, 2013
Last Updated: Wednesday, December 04, 2013
Bookmark and Share
To rapidly produce consistent cancer immunotherapy batches and cell banks.

TAP Biosystems has announced that its Fill-It™, automated benchtop vial filling system is being routinely used at an innovative cell therapy company developing novel cancer immunotherapies, to improve processing speed and throughput of large batches of cells in cryovials for use as master cell banks or as cell-based immunotherapies.

Scientists at the company are using Fill-It to produce batches of around 1000 cryovials per run, containing 0.65ml of up to 100 million cell/ml of an immunotherapy product candidate, consisting of two allogeneic cancer cell lines.

Fill-It aseptically processes these temperature-sensitive cells at high throughput, enabling vials to be uncapped, filled and recapped at speed, so they can be put them in the freezer quickly to maintain optimum cell quality.

Stephen Guy, Fill-It Product Manager at TAP, explained: “The company wanted to automate their vial processing as it was taking around one and half hours for a scientist to produce a batch of 1000 vials. As well as the RSI issues associated with uncapping and recapping this number of vials, it was difficult to maintain product consistency across the batch. Using the Fill-It automated system, batches of vials are processed at speed with minimal human interaction. The cells are dispensed using sterile, GMP-certified disposable tubing and the vials get into the freezer quickly. This results in cell numbers being maintained at consistently high quality until the vials are thawed for use.”

Guy added: “We are delighted our Fill-It system is helping such an innovative cell therapy company to ensure their critical cancer cell banks and cancer immunotherapies are maintained in top condition. This firm’s routine application of our technology demonstrates to cell therapy companies looking for a method of rapidly producing large batches of consistent quality cells that a Fill-It system is a tried and trusted choice.”


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 4,000+ scientific posters on ePosters
  • More than 5,300+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
New Mechanism to Control Human Viral Infections Discovered
Researchers discover long sought after mechanism in human cells that could help treat diseases caused by viruses.
Study Reveals New Role for Hippo Pathway in Suppressing Cancer Immunity
Hippo pathway signaling regulates organ size by moderating cell growth, apoptosis and stem cell renewal, but dysregulation contributes to cancer development.
RNAi Activated in Response to Influenza
Discovery could lead to better ways of combating serious infections, including Ebola and Zika.
Gene Therapy Maintains Clotting Factor for Hemophilia Patients
Following a single gene therapy dose, the highest levels of an essential blood clotting factor IX were observed in hemophilia B patients.
Transporting Microscopic Cargo Between Human Cells
Scientists have developed a virus-inspired delivery system for material transport between cells.
Improving Drug Production with Computer Model
A model has been developed that can be used to improve and accelerate the production of biotherapeutics, cancer drugs, and vaccines.
Turning Off Asthma Attacks
Researchers discover a critical cellular “off” switch for the inflammatory immune response that causes asthma attacks.
New Strategy May Drop Cancer’s Guard
Scientists eye ways to deconstruct tumors’ protective wall with current diabetes drug.
Scientists Identify Unique Genomic Features in Testicular Cancer
The findings may shed light on factors in other cancers that influence their sensitivity to chemotherapy.
Smart Patch Releases Blood Thinners When Needed
Researchers have developed a smart patch that activelly monitors a patient's blood and releases blood thinning drugs when necessary.
SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
4,000+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,300+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!