Corporate Banner
Satellite Banner
RNAi
Scientific Community
 
Join | Sign in
Home>Resources>Posters

  Posters

THe AtSCL26 transcription factor controls cross-talk between GA and N root architecture in Arabidopsis thaliana roots
Beatriz Lagunas, Anthony D. Carter, Dafyd Jenkins and Miriam Gifford

Phenotypic and molecular evidence supports the hypothesis that developmental program enabling nodule formation arose during evolution from a lateral root ‘blueprint’ pre-existing in all higher plants . We reasoned that analyzing Arabidopsis genes orthologous to regulators of nodulation could shed insight on control of lateral root development. This led us to the discovery that an Arabidopsis GRAS family transcription factor controls lateral root development under specific nitrogen conditions.

More information
LOHA Comprehensive Assay for Single Nucleotide Polymorphism, Copy Number Variants and Loss of Heterozygosity Using SureSelect Target Enrichment
Kyeong Soo Jeong, Arjun Vadapalli, Ashutosh Ashutosh, Paula Costa, Brian Peter, Stephanie Fulmer-Smentek, Magnus Isaksson, Jayati Ghosh, Douglas Roberts, Holly Hogrefe

Here we describe a comprehensive assay that enables researchers to identify SNP, INDEL, CNV, and LOH using SureSelect target enrichment. This design can be employed as a standalone entity or in concert with other bait designs for SNP and INDEL detection. We also describe methods for data analysis and visualization.

More information
An examination of specific cellular organelle-targeting nanotags using combined 3D Raman and SERS imaging
Katherine Lau, Sarah McAughtrie, Karen Faulds, Duncan Graham

We investigated the specific targeting of endoplasmic reticulum and trans-Golgi network in Chinese hamster ovarian cells using functionalised nanotags. The targeting was examined using the combined 3D SERS and Raman imaging method.

More information
SOFT DEVICES FOR HEALTHCARE MONITORING APPLICATIONS
Laura López, Carlos Carenas, Carme de Haro, Cristina Casellas, Elisenda Reixach, Marta Cot, Rosa Rodriguez, Paul Lacharmoise, Úrbez Santana

Printed Electronics allow the creation of new and innovative functionalized textile products, in the demanding and highly specialized world of Medical Devices. The main aim of this whole new sector is to produce wearable, conformable, flexible and low-cost textile-based devices bringing innovative solutions to different markets.

More information
The Power Decoder simulator for the evaluation of pooled shRNA screen performance
Jesse Stombaugh, Abel Licon, Žaklina Strezoska, Joshua Stahl, Sarah Bael Anderson, Michael Banos, Anja van Brabant Smith, Amanda Birmingham, Annaleen Vermeulen

Power Decoder (written in R and Python) simulates shRNA pooled screening experiments in silico to allow for the estimation of a screen’s statistical power. Populations of shRNAs were engineered in such a way that the magnitude of depletion and enrichment was known, then using the negative binomial distribution, an in silico model was developed to successfully resemble data from an actual laboratory experiment.

More information
Knockdown of long noncoding RNAs in breast cancer
1 Jennii Luu, 2 Jesper Maag, 1 Yanny Handoko, 3 Richard Redvers, 3,4 Robin L. Anderson, 5 Maren M. Gross , 2 Marcel E. Dinger, and 1,3 Kaylene J. Simpson 1 Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre; 2 Genome Informatics, The Kinghorn Cancer Centre, The Garvan Institute of Medical Research; 3 Metastasis Research Laboratory, Peter MacCallum Cancer Centre, 4 Sir Peter MacCallum Department of Oncology, University of Melbourne;

RNAi global collaboration study using Lincode siRNA in a primary screen of tumor and nontumor breast cell lines. Hundreds of lncRNAs are found to affect viability and cell morphology of breast cancer. Presented at Keystone Symposia on Long Noncoding RNAs: From Evolution to Function, Mar 15 - Mar 20, 2015.

More information
Improved Small RNA Library Preparation Workflow for Next-Generation Sequencing
Sabrina Shore, Jordana Henderson, Anton McCaffrey, Gerald Zon, Richard Hogrefe

We describe an optimized small RNA NGS library prep workflow using chemically modified adapters which suppresses adapter dimers, allows for RNA inputs down to 1 ng and eliminates the need for a gel purification step, thus allowing full automation not previously possible.

More information
Fluorescent Nanoprobes Confined in a Drop as a novel Sensing Platform for Detection of Metal Species at Trace Level
Carlos Bendicho, Isabel Costas-Mora, Vanesa Romero, Isela Lavilla

In the last years, a great interest has arisen concerning the design and development of new optical probes for the sensitive and selective detection of chemical species making use of miniaturized and environmental friendly methods. In this sense, quantum dots (QDs) and metal nanoclusters (NCs) have important optical properties to be applied in analytical systems as fluorescent probes.

More information
Specificity of highly potent miRNA inhibitors
Barbara Robertson, Andrew Dalby, Yuriy Fedorov, Jon Karpilow, Anastasia Khvorova1, Devin Leake, Annaleen Vermeulen

miRNA inhibitors are invaluable tools for elucidating the roles of miRNAs. However, potent inhibitors may also affect other miRNAs. To understand the potential cross-reactivity of miRNA inhibitors, various miRNA inhibitor designs were systematically tested. We demonstrate that mismatches both within and outside the seed region of the miRNA interfere with inhibition. Our findings indicate that features important for natural miRNA target recognition are also important for inhibitor specificity.

More information
Targeting Cancer Stem Cell-Related miRNAs for Prostate Cancer Therapy
ANSHIKA NIKITA SINGH, MEGHNA BARUAH, NEETI SHARMA

The poster focuses on the pivotal function of miRNAs in tumorigenesis by regulation of self renewal and apoptosis via cancer stem cell signalling pathways with special focus on their regulation of Epithelial to Mesenchymal transition in metastatic prostate cancer.

More information
<< 1 2 3 4 5 6 7 >>
Showing Results 1 - 10 of 184
Scientific News
Hundreds Of Cancer Possibilities Arise From Common Skin Mole Mutation
A Houston Methodist-led team of international scientists has identified hundreds of possible new genes in mice that could transform benign skin growths into deadly melanomas.
Quotient Clinical Completes Innovative First-In-Human Program
First-in-human clinical program designed to develop an optimal oral formulation.
Results from the Sidney Kimmel Cancer Center at Thomas Jefferson University
The Sidney Kimmel Cancer Center has published results of its work evaluating the potential for ANGLE’s Parsortix system.
Gene Variant Linked to Smoking Longer, Getting Lung Cancer Sooner
Smokers with a particular variation in a nicotine receptor gene were more likely to continue smoking for four years.
Scientists Discover Protein That Boosts Immunity to Viruses and Cancer
Researchers now developing a gene therapy designed to boost the infection-fighting cells.
NIH Study Finds Genetic Link for Rare Intestinal Cancer
Researchers recommend screening for people with family history.
Potential For Prediction Of Progression For Early Form Of Breast Cancer
Scientists in Manchester have identified a way to potentially predict which patients with an early form of breast cancer will experience disease progression.
Understanding the Behaviour of Cells in Cancer Metastasis
LaVison BioTec report on the research of Professor Kurt I Anderson and his groups' studies of cell migration in the context of cancer metastasis at the Beatson Institute for Cancer Research.
Brain Tumor Weakness Identified
Discovery could offer a new target for treatment of glioblastoma.
Scientists Unveil Sex-Linked Control of Genes
Many proteins interact with an RNA molecule called Xist to coat and silence one X chromosome in every female cell.
SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters