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A novel DNA amplification method based on silicon microring resonator for rapid detection of genetic alteration in the point-of care (POC) field of cancers

Nucleic acid testing plays a critical role in molecular diagnosis[1-2]. Due to the low amounts of DNA obtained in clinical samples, the amplification of DNA is an essential step in most NAT methods [3].

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The Challenges of Relieving Cancer Pain: A Literature Review
Rayna Patel

This study aims to explore the discrepancy between the increasing array of treatments for cancer pain, as well as the evidence that it can be managed effectively in the majority of cases, and its persisting prevalence.

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Evaluation of 2012 Bowel Cancer Awareness and Early Diagnosis Campaign at a District General Hospital
M Alkhusheh, H Asalieh, N Smith

Following the regional Be Clear on Cancer campaign, the Department of Health launched a national bowel cancer awareness campaign from 30 January 2012. The campaign ran until the end of March.

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FDG PET/CT Utility in Gynecologic Malignancies: A comprehensive review of anatomy, pathways of metastatic spread and scan findings
Nicholas Plaxton, MD, Aruna Polsani, MD, Raghuveer Halkar, MD, Karen Godette, MD, Barron, Bruce, MD

Our objective was to review the five major gynaecologic cancers (cervical, ovarian, uterine, vaginal, and vulvar) and demonstrate the role of FDG PET/CT in diagnosis, surveillance, FIGO staging and treatment strategy.

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FDG PET/CT Characteristics of Adrenal Benign and Malignant Lesions
Nicholas Plaxton, MD, Raghuveer Halkar, MD, Bruce Barron, MD

We selected FDG PET/CT cases with strong key representative findings to help illustrate benign and malignant adrenal lesions. Tabular review of PET SUV values, Hounsfield units and lesion size in the different cases will be discussed.

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Discovery of Conserved Domains for Development of Functional Markers and Identification of microRNAs from Drought Responsive Expressed Sequence Tags (ESTs) in Chickpea (Cicer arietinum L.)
Mandape M, Saikumar K, Dudhe MY, Kumar J, Meena HP, Chauhan J, Afroz A

This stidy identified that conserved domains or gene families from the ESTs could be utilized for the identification of gene-targeted markers and for development of functional markers to accelerate marker assisted backcross breeding in chickpea.

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Mohamad Al-shammari wins Poster Award at System Biology Europe 2012
Mohamad Al-Shammari

Mohamad Al-shammari wins Poster Award at System Biology Europe 2012

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Gene Expression from Pseudourine and 5-Methylcytidine Modified Messenger RNA
Jiehua Zhou, Maggie L. Bobbin, Julie R. Escamilla-Powers, Anton P. McCaffrey and John J. Rossi

Study objective was to develop methodologies for gram scale synthesis of messenger RNA (mRNA) for gene therapy applications, as well as scalable purification methods that yield highly expressed, persistent and non-toxic mRNA.

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A Dynamic Glucose-Sensitive Insulin Delivery System: poly(NIPAm/MAA) Nanoparticle Membrane
Ji-Sung Kim

It can be stated that there exists a spatial and temporal differential paradox of dynamic glucose levels in the body. Conventional insulin injections are unable to resolve this paradox.

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Scientific News
Revealing the Genetic Causes of Bowel Cancer
A landmark study has given the most detailed picture yet of the genetics of bowel cancer — the UK's fourth most common cancer.
Self-Assembling Protein Shell for Drug Delivery
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Fighting Resistant Blood Cancer Cells
Biologists present new findings on chronic myeloid leukemia and possible therapeutic approaches.
Tumor Cells Develop Predictable Characteristics
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Guided Chemotherapy Missiles
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Innovation to speed the routine.
What Makes a Good Scientist?
It’s the journey, not just the destination that counts as a scientist when conducting research.
Biomarkers That Could Help Give Cancer Patients Better Survival Estimates Discovered
UCLA research may also help scientists suppress dangerous genetic sequences.
Body’s Own Gene Editing System Generates Leukemia Stem Cells
Inhibiting the editing enzyme may provide a new therapeutic approach for blood cancers.
A New Approach to Chemical Synthesis
Communesins, originally found in fungus, could hold potential as cancer drugs.
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