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A novel DNA amplification method based on silicon microring resonator for rapid detection of genetic alteration in the point-of care (POC) field of cancers

Nucleic acid testing plays a critical role in molecular diagnosis[1-2]. Due to the low amounts of DNA obtained in clinical samples, the amplification of DNA is an essential step in most NAT methods [3].

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The Challenges of Relieving Cancer Pain: A Literature Review
Rayna Patel

This study aims to explore the discrepancy between the increasing array of treatments for cancer pain, as well as the evidence that it can be managed effectively in the majority of cases, and its persisting prevalence.

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Evaluation of 2012 Bowel Cancer Awareness and Early Diagnosis Campaign at a District General Hospital
M Alkhusheh, H Asalieh, N Smith

Following the regional Be Clear on Cancer campaign, the Department of Health launched a national bowel cancer awareness campaign from 30 January 2012. The campaign ran until the end of March.

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FDG PET/CT Utility in Gynecologic Malignancies: A comprehensive review of anatomy, pathways of metastatic spread and scan findings
Nicholas Plaxton, MD, Aruna Polsani, MD, Raghuveer Halkar, MD, Karen Godette, MD, Barron, Bruce, MD

Our objective was to review the five major gynaecologic cancers (cervical, ovarian, uterine, vaginal, and vulvar) and demonstrate the role of FDG PET/CT in diagnosis, surveillance, FIGO staging and treatment strategy.

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FDG PET/CT Characteristics of Adrenal Benign and Malignant Lesions
Nicholas Plaxton, MD, Raghuveer Halkar, MD, Bruce Barron, MD

We selected FDG PET/CT cases with strong key representative findings to help illustrate benign and malignant adrenal lesions. Tabular review of PET SUV values, Hounsfield units and lesion size in the different cases will be discussed.

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Discovery of Conserved Domains for Development of Functional Markers and Identification of microRNAs from Drought Responsive Expressed Sequence Tags (ESTs) in Chickpea (Cicer arietinum L.)
Mandape M, Saikumar K, Dudhe MY, Kumar J, Meena HP, Chauhan J, Afroz A

This stidy identified that conserved domains or gene families from the ESTs could be utilized for the identification of gene-targeted markers and for development of functional markers to accelerate marker assisted backcross breeding in chickpea.

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Mohamad Al-shammari wins Poster Award at System Biology Europe 2012
Mohamad Al-Shammari

Mohamad Al-shammari wins Poster Award at System Biology Europe 2012

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Gene Expression from Pseudourine and 5-Methylcytidine Modified Messenger RNA
Jiehua Zhou, Maggie L. Bobbin, Julie R. Escamilla-Powers, Anton P. McCaffrey and John J. Rossi

Study objective was to develop methodologies for gram scale synthesis of messenger RNA (mRNA) for gene therapy applications, as well as scalable purification methods that yield highly expressed, persistent and non-toxic mRNA.

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A Dynamic Glucose-Sensitive Insulin Delivery System: poly(NIPAm/MAA) Nanoparticle Membrane
Ji-Sung Kim

It can be stated that there exists a spatial and temporal differential paradox of dynamic glucose levels in the body. Conventional insulin injections are unable to resolve this paradox.

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Showing Results 11 - 20 of 140
Scientific News
Bowel Cancer Breakthrough May Benefit Thousands of Patients
Researchers at Queen’s University have discovered how two genes cause bowel cancer cells to become resistant to treatments used against the disease.
Study Finds Low Oxygen Environment Helps Tumors Silence Critical Genes
The study led by Yale Cancer Center may provide clues to how some aggressive cancers turn off, or silence, genes critical to suppressing tumors.
Researchers Uncover New Cancer Cell Vulnerability
The research showed that telomerase-expressing cells depend upon a gene named p21 for their survival.
Self-assembling Nanoparticle Could Improve MRI Scanning for Cancer Diagnosis
Scientists have designed the nanoparticle that targets tumours, to help doctors diagnose cancer earlier.
Wisconsin Scientists Find Genetic Recipe to Turn Stem Cells to Blood
The ability to reliably and safely make in the laboratory all of the different types of cells in human blood is one key step closer to reality.
Capturing Cancer: A Powerful New Technique for Early Diagnosis
Researchers describe an innovative technique for early disease detection, which they call immunosignaturing.
Study Identifies Novel Genomic Changes in the Most Common Type of Lung Cancer
TCGA finds mutations in a key cancer-causing pathway, expanding targets for existing drugs.
Low Doses of Arsenic Cause Cancer in Male Mice
NIH researchers found that arsenic in drinking water develop lung cancer.
Brain Tumor Invasion Along Blood Vessels May Lead to New Cancer Treatments
NIH-funded researchers find brain tumor cells disrupt the brain’s protective barrier, offering potential avenues for therapy.
Revealing the Role of “Precocious” Dendritic Cells in Inflammatory Response
Discovery makes it possible for researchers to explore how these “precocious” cells escalate the body’s immune response when the body is under attack.
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