Small Interfering RNA (siRNA)-mediated gene silencing is an exciting and valuable tool for studying gene function. However, most researchers are limited by their ability to test only a handful of chemically synthetic siRNAs due to high cost and lack of design guidance. Dicer siRNA Generation Kit allows cost-effective production of siRNAs targeted against entire gene sequences for efficient gene silencing. Harness the Natural Process. Most researchers purchase 3 to 8 chemically synthesized double-stranded siRNAs for each gene of interest to test whether they can get any strong gene silencing effect. This means synthesizing and processing 6 to 16 RNA oligonucleotides at a relatively high cost. The Dicer siRNA Generation Kits mimic the natural RNA interference process by using the recombinant human dicer enzyme to cleave in vitro transcribed dsRNA into a pool of 20 to 21-bp siRNAs.
Genlantis offers two different types of kits to generate siRNA: the original Dicer siRNA Generation Kits, and the more rapid Turbo Dicer siRNA Generation Kits. Additionally, multiple configurations and component kits of either the original or Turbo Dicer kits are offered to make these kits as convenient and cost effective as possible.
For the utmost in convenience and efficiency, Genlantis also offers one of the most widely-used and effective siRNA delivery reagents on the market, the GeneSilencer™ Transfection Reagent. The GeneSilencer reagent is provided as a prepackaged component of either Dicer siRNA generation kits, or it can be purchased separately in many different sizes and configurations. The GeneSilencer™ siRNA Transfection Reagent ensures efficient delivery of precious siRNA samples, no matter which method is used to produce these siRNAs.
Retractable Protein Nanoneedles The ability to control the transfer of molecules through cellular membranes is an important function in synthetic biology; a new study from researchers at Harvard’s Wyss Institute for Biologically Inspired Engineering and Harvard Medical School (HMS) introduces a novel mechanical method for controlling release of molecules inside cells.Advancing Synthetic Biology Living systems rely on a dizzying variety of chemical reactions essential to development and survival. Most of these involve a specialized class of protein molecules — the enzymes.NIH Researchers Identify Striking Genomic Signature for Cancer Institute has identified striking signature shared by five types of cancer.CRI Develops Innovative Approach for Identifying Lung Cancer Institute has developed innovative approach for identifying processes that fuel tumor growth in lung cancer patients.Counting Cancer-busting Oxygen Molecules Researchers from the Centre for Nanoscale BioPhotonics (CNBP), an Australian Research Centre of Excellence, have shown that nanoparticles used in combination with X-rays, are a viable method for killing cancer cells deep within the living body.Crowdfunding the Fight Against Cancer From budding social causes to groundbreaking businesses to the next big band, crowdfunding has helped connect countless worthy projects with like-minded people willing to support their efforts, even in small ways. But could crowdfunding help fight cancer?
Cancer Cells Kill Off Healthy Neighbours Cancer cells create space to grow by killing off surrounding healthy cells, according to UK researchers working with fruit flies.Cancer Drug Target Visualized at Atomic Resolution New study using cryo-electron microscopy shows how potential drugs could inhibit cancer.Genetic Mechanism Behind Cancer-Causing Mutations Researchers at Indiana University has identified a genetic mechanism that is likely to drive mutations that can lead to cancer.Future of Medicine Could be Found in a Tiny Crystal Ball A Drexel University materials scientist has discovered a way to grow a crystal ball in a lab. Not the kind that soothsayers use to predict the future, but a microscopic version that could be used to encapsulate medication in a way that would allow it to deliver its curative payload more effectively inside the body.