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  Application Notes

Dual-Glo Luciferase Reporter-Gene Assay on the SpectraMax M5, LMax II3

Molecular Devices
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Efficient Delivery of siRNA in Human Renal Cell Carcinoma Cell Line Us

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FabRICATOR® - perfect F(ab?)2 fragments in minutes

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First siRNA Library Screening in Hard-to-Transfect HUVEC and Jurkat Ce

Amaxa GMBH
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Knockdown of BACE-1, an Alzheimer’s Disease Drug Target, with NIMT®FeO

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Measurement of Proteasome Inhibition in Live Cells in Molecular Device

Molecular Devices
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NIMT®FeOfection|PURPLE in siRNA Delivery into HEK293 Cells

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Nucleofection® Enables Luciferase Reporter Assays in Primary Cells and

Amaxa GMBH
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Optimized cell culture

Tecan Group Ltd.
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Scientific News
New Gene Therapy for Vision Loss From a Mitochondrial Disease
NIH-funded study shows success in targeting mitochondrial DNA in mice.
Predictive Model for Breast Cancer Progression
Biomedical engineers have demonstrated a proof-of-principle technique that could give women and their oncologists more personalized information to help them choose options for treating breast cancer.
Specific Variations in RNA Splicing Linked to Breast Cancer
Researchers have identified cellular changes that may play a role in converting normal breast cells into tumors. Targeting these changes could potentially lead to therapies for some forms of breast cancer.
Gene Expression: A Snapshot of Stem Cell Development
New genes found that regulate development of stem cells.
Assessing Cancer Patient Survival and Drug Sensitivity
RNA editing events another way to investigate biomarkers and therapy targets.
Editing Genes to Create HIV Killers
Seattle scientists have managed to genetically transform human cells in the lab from HIV targets to HIV killers, and the technique could have implications for cancer and other diseases.
Researchers Disguise Drugs As Platelets to Target Cancer
Researchers have for the first time developed a technique that coats anticancer drugs in membranes made from a patient’s own platelets.
A New Single-Molecule Tool to Observe Enzymes at Work
A team of scientists at the University of Washington and the biotechnology company Illumina have created an innovative tool to directly detect the delicate, single-molecule interactions between DNA and enzymatic proteins.
Milestone Single-Biomolecule Imaging Technique May Advance Drug Design
The first nanometer resolved image of individual tobacco mosaic virions shows the potential of low-energy electron holography for imaging biomolecules at a single particle level; a milestone in structural biology and a potential new tool for drug design.
Opening the Door to Safer, More Precise Cancer Therapies
New method regulates when, and how strongly, cancer-killing therapeutic T cells are activated.

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