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Horizon Discovery: The Power of Personal...
Gene Drives...An ULTImate Y2H project at Hybrigenics S...Western Blotting Protocol ...

Featured Products
Featured Product - AvaRaman-Supreme
AvaRaman-Supreme

Webcasts
Webcast - Discovery of Potent and Selective Inhibitors of Monopolar Spindle 1 (MPS1) KinaseDiscovery of Potent and Selective Inhibitors of Monopolar Spindle 1 (MPS1) Kinase
Rob van Montfort, The Institute of Cancer Research, speaking at Discovery Chemistry Congress 2015.
Webcast - Fragment-based Approach to Multi-target CompoundsFragment-based Approach to Multi-target Compounds
Eugen Proschak, Goethe University, speaking at Discovery Chemistry Congress 2015.

Market Reports
Analytical Instrument Market in the US 2014-2018
Infinity Research

TechNavio's report focuses on the US and has been prepared based on an in-depth market analysis with inputs from industry experts.
Atomic Spectroscopy Market by Technology & Application - Competitive Landscape, Global Forecasts & Trends to 2018
MarketsandMarkets

The global atomic spectroscopy market was valued at an estimated $4.02 billion in 2013 and is expected to grow at a CAGR of 6.4%.
Molecular Spectroscopy Market by Technology & Application - Forecast to 2018
MarketsandMarkets

Over the years, the molecular spectroscopy market, comprising instruments, consumables, and services, has witnessed various technological advancements. These advancements have led to a growth in the number of molecular spectroscopy applications.
Multi-Mode Microplate Reader Trends 2013
HTStec

This market report summarizes the results of HTStec’s 4th industry-wide global web-based benchmarking survey on multi-mode microplate readers carried out in September 2013.
Biomarkers
RI Technologies

This report on focuses on the different types of biomarkers and their impact on various disease areas. The study also provides global market analysis for biomarkers by disease area and by prominent biomarker identification technologies.
Pathways to Efficient Drug Development - Advances in Modeling and Simulation Outcomes to Fuel Pipeline Productivity
GBI Research

The report examines the reasons why the pharmaceutical industry is looking for improvements in efficiency whilst acknowledging that pharmaceutical R&D remains a long and risky process. It looks in detail at precompetitive research and evaluates how the industry is pulling together to research solutions to problems that are common to all companies.
Life Science Software 2013: Markets and Opportunities
Biopharm Reports

This reports into in the life science field examines the use of specialist software and databases relating to the conduct of PCR, DNA sequencing, DNA microarray, flow cytometry, mass spectrometry and disease biomarker studies. The studies were carried out to assist software developers and vendors to identify market opportunities in these fields.
Lab Instrument Rental Trends 2012
HTStec

This market report summarizes the results of HTStec’s industry-wide global web-based benchmarking survey on lab instrument rental carried out in September 2012.
Single Cell Omics 2011
Select Biosciences Ltd

The single cell Omics revolution is the potential transformation of cellular heterogeneity from a source of noise to a source of new, as yet hidden discoveries.
Scientific News
Shining A New Light On The Immune System
Scientists at the University of St Andrews have developed a revolutionary method of identifying cells of the immune system with “molecular fingerprints” which could pave the way for the rapid detection of conditions such as leukaemia and lymphoma from a small blood sample.
Holes in Gold Enhance Molecular Sensing
Electrochemical techniques produce tuneable porous gold films, where the empty spaces enhance light scattering and sensing signals.
Damming hemorrhagic diseases
A potential mechanism to combat diseases caused by haemorrhagic fever viruses has been discovered by researchers.
Cause of Wheat Resistance to Scab Discovered
Synchrotron research could give rise to better yields and varieties.
New Research Into Health Benefits Of Coffee
New research has brought us closer to being able to understand the health benefits of coffee.
Urine Profiles Provide Clues To How Obesity Causes Disease
Scientists have identified chemical markers in urine associated with body mass, providing insights into how obesity causes disease.
Using Raman to Study Graphene
Renishaw inVia system will be used for metrology studies and to set standards for graphene.
Shape-Shifting Molecule Tricks Viruses Into Mutating Themselves To Death
Study uses two-dimensional infrared spectroscopy to help distinguish between normal and shape-shifted structures.
NMR ‘Fingerprinting’ for Monoclonal Antibodies
Study by NIST researchers shows the use of NMR spectroscopy for measuring the structural congfiguration of monoclonal antibodies.
Plant Cell Structure Discovery Could Lead to Improved Renewable Materials
Researchers investigate the polymer xylan.
Business News
Malvern To Present New Research at ISFRS
Malvern puts the spotlight on cutting edge analytical strategies at ISFRS 2015.
Analytik Jena AG Receives Major Order from China
Delivery of EUR 2.5 m in instruments from both core business units of Analytical Instrumentation and Life Science.
UC Santa Cruz Biomedical Research Facility Wins $2 Million NIH Grant
Grant awarded for a powerful new instrument used by chemists and biochemists.
Rigaku Awarded ISO Certification
Company receives ISO 9001:2008, certification from the National Standards Authority of Ireland (NSAI) for its new manufacturing facility.
Rigaku Announce New President & COO
Company appoints Mr. Yoichi Yokomizo as Chief Operating Officer of RAH.
Agilent Announces New CEO Mike McMullen
McMullen elected as chief executive officer by Company’s board of directors.
Renishaw and Bruker Team Up
Companies to host a series of workshops on TERS and co-localized AFM Raman.
Pittcon 2015 Announces Exposition Highlights
This year’s exposition welcomes 127 first-time exhibiting companies.
Medimmune & NIST Partner To Advance Development Of Biological Therapies
Five year partnership will support research to help advance biopharmaceutical development and production.
Keck Foundation to Fund Purdue Research into Spectroscopic Imaging
Ji-Xin Cheng leads a Purdue team awarded a $1 million W.M. Keck Foundation grant to develop a new type of imaging technology for cell and tissue analysis that could bring advanced medical diagnostics.

Events
63rd ASMS Conference on Mass S
31 May 2015
63rd ASMS Conference on Mass S ...
ICP 2015 - 27th  International
28 Jun 2015
ICP 2015 - 27th  International ...
EUROMAR 2015
05 Jul 2015
EUROMAR 2015 ...
Analitica Latin America 2015
22 Sep 2015
Analitica Latin America 2015 ...

ePosters
Bovine RNA-seq data analysis of liver and pituitary gland
(1) Functional Genomics Lab. Faculty of Biology and Environmental Protection, Nicolaus Copernicus University, Torun, Poland, (2) Interdisciplinary Centre of Modern Technology, Nicolaus Copernicus Uni

Two key applications of RNA-seq i.e., i) transcriptome read mapping to a reference genome and ii) SNP detections were investigated to analysis of bovine liver and pituitary gland transcriptome. Here, we have presented ONLY the obtained results of bovine pituitary gland.
A proteomic analysis of p27kip1-binding proteins reveals a putative role in transcription regulation through RNA polymerase II interaction
1.-Department of Cell Biology, Immunology and Neurosciences, University of Barcelona-IDIBAPS, Barcelona, Spain 2.-INSERM UMR1037-Cancer Research Center of Tolouse, Universite de Tolouse, CNRS ERL5294

A proteomic analysis of p27kip1-binding proteins reveals a putative role in transcription regulation through RNA polymerase II interaction
Innovative technology that enables RNAi in difficult to transfect cells
GE Healthcare Dharmacon, Inc.

Investigations at Dharmacon have led to the development of innovative siRNA molecules that can be delivered into difficult-to-transfect cells without additional lipid reagents, virus, or instruments. This technology, Accell siRNA reagents, enables gene knockdown for functional genomic studies in a wide variety of cell types. In some instances, cells can be continuously dosed with Accell siRNAs to enable target gene knockdown for extended durations.
THe AtSCL26 transcription factor controls cross-talk between GA and N root architecture in Arabidopsis thaliana roots
University of Warwick

Phenotypic and molecular evidence supports the hypothesis that developmental program enabling nodule formation arose during evolution from a lateral root ‘blueprint’ pre-existing in all higher plants . We reasoned that analyzing Arabidopsis genes orthologous to regulators of nodulation could shed insight on control of lateral root development. This led us to the discovery that an Arabidopsis GRAS family transcription factor controls lateral root development under specific nitrogen conditions.
LOHA Comprehensive Assay for Single Nucleotide Polymorphism, Copy Number Variants and Loss of Heterozygosity Using SureSelect Target Enrichment
Agilent Technologies, Diagnostics and Genomics Group

Here we describe a comprehensive assay that enables researchers to identify SNP, INDEL, CNV, and LOH using SureSelect target enrichment. This design can be employed as a standalone entity or in concert with other bait designs for SNP and INDEL detection. We also describe methods for data analysis and visualization.
An examination of specific cellular organelle-targeting nanotags using combined 3D Raman and SERS imaging
Renishaw plc,

We investigated the specific targeting of endoplasmic reticulum and trans-Golgi network in Chinese hamster ovarian cells using functionalised nanotags. The targeting was examined using the combined 3D SERS and Raman imaging method.

DETERMINATION OF THE QUALITY OF ACTIVE INGREDIENTS IN PAIN KILLERS USING GC-MS
Jomo Kentyatta University of Agriculture and Technology (Kenya), and Foundation of Analytical Science and Technology in Africa (UK).

From this study, the pain killers sampled were found to have large error bars suggesting that there exist counterfeit drugs in the market. The brands mostly affected for analysis of acetaminophen were panadol, action, P500, P5500, elymol and neladol. The error bars for caffeine analysis were quite low indicating that all tablets either counterfeit or original maintained the same amount of this active ingredient.
DETERMINATION OF ESSENTIAL AND HEAVY METALS IN KENYAN HONEY BY ATOMIC ABSORPTION AND EMMISSION SPECTROSCOPY
Jomo Kenyatta University of Agriculture and Technology

Generally, honey samples recorded very low concentrations of As compared to the other heavy metals determined in this study. The highest concentration of As was recorded in honey sample from Nairobi with a value of 0.03±0.01 ppm. All the values recorded were within the KEBS permitted value of 0.5 ppm in food according to Kenya Bureaue of Standards, 1996.
Prospecting For Iron and Titanium Using Termitaria
Jomo Kenyatta University of Agriculture and Technology

This study demonstrated elevated levels of the two metals (that is iron and titanium) in termitaria soil compared to the surrounding soils. Termitaria are very important bioturbators and can therefore be used as preliminary step in mineral prospecting since they provide an indication of the potential of the positive anomaly, and enables a judgment on the scale of the metal accumulation
Improved Small RNA Library Preparation Workflow for Next-Generation Sequencing
TriLink BioTechnologies

We describe an optimized small RNA NGS library prep workflow using chemically modified adapters which suppresses adapter dimers, allows for RNA inputs down to 1 ng and eliminates the need for a gel purification step, thus allowing full automation not previously possible.
Application Notes
Aseptic Identification of Polysorbates using Handheld Raman
Rigaku Raman Technologies

As polysorbates are reactive to light and air, packaging is usually in thick, dark, amber bottles. This makes the identification process more difficult, as opening the container could compromise the sterility and quality of these materials. Handheld Raman is capable of identifying these materials without any sampling or preparation.
Herbal Materials and Natural Foods Analysis with Handheld Raman
Rigaku Raman Technologies

Dietary supplement manufacturers are required to use at least one appropriate test method to verify the identity of any component or excipient that is used in the manufacturing of a dietary supplement, as well as confirmation of identity of the product.
Cell Culture Media Identification In Biopharmaceuticals With Handheld Raman
Rigaku Raman Technologies

This application note discusses the identification of cell culture media using Raman analysis.
Drug Product Identification Using Handheld Raman
Rigaku Raman Technologies

Handheld Raman spectroscopy is well accepted as a technique for raw material and excipient identification within the pharmaceutical industry. Using the correct Raman excitation wavelength can extend its capabilities into the areas of drug substance and drug product identification.
Pharmaceutical Excipients Identification With Handheld Raman
Rigaku Raman Technologies

This application note discusses the identification of pharmaceutical excipients using Raman analysis.
Rapid Detection of Counterfeit and Substandard Medicines with Handheld Raman
Rigaku Raman Technologies

This application note discusses counterfeit screening using Raman analysis.
Forensic Analysis of an Artificial Sweetener Commonly Employed in Hoax Powder Attacks using Morphologically Directed Raman Spectroscopy
Malvern Instruments Limited

This application note details how Morphologically Directed Raman Spectroscopy (MDRS) using the Morphologi G3-ID can be applied to the forensic identification of commercially sourced white powders commonly used in hoax powder attacks.
Pharmaceutical Excipient Characterization
Malvern Instruments Limited


Quantifying shear thinning behavior on a rotational rheometer using the power law model
Malvern Instruments Limited

This application note shows how the power law model can be used to quantify shear thinning behavior and for comparing between products and formulations.
Quantifying viscosity recovery following extrusion or spraying using thixotropy assessment on a rotational rheometer
Malvern Instruments Limited

This app note shows how a three step shear rate test can be used to evaluate the extent of viscosity recovery following extrusion from a tube or bottle.
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