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Webcasts
Webcast - Imaging Biomarkers - Future or RealityImaging Biomarkers - Future or Reality
Edwin van Beek, University of Edinburgh, speaking at Diagnostics & Biomarkers 2015.
Webcast - Discovery of Potent and Selective Inhibitors of Monopolar Spindle 1 (MPS1) KinaseDiscovery of Potent and Selective Inhibitors of Monopolar Spindle 1 (MPS1) Kinase
Rob van Montfort, The Institute of Cancer Research, speaking at Discovery Chemistry Congress 2015.

Market Reports
Single Cell Omics 2011
Select Biosciences Ltd

The single cell Omics revolution is the potential transformation of cellular heterogeneity from a source of noise to a source of new, as yet hidden discoveries.
Scientific News
Fast, Simple Test for Colitis
A minimally invasive screening for ulcerative colitis using emerging infrared technology could be a rapid and cost-effective method for detecting disease that eliminates the need for biopsies and intrusive testing of the human body.
Crucial Reaction for Vision Revealed
Scientists have tracked the reaction of a protein responding to light, paving the way for a new understanding of life's essential reactions.
Using Light To Examine The Lungs Of Premature Babies
New technique has potential to replace the use of X-rays to see how much air babies’ lungs contain.
Novel Spectroscopy by Using Aberrations
Flaws inherent to electron microscopy used to create probes for performing novel atomic-level spectroscopy.
Effective Identification of Low-Gliadin Wheat Lines
Researchers have demonstrated the use of NIRS to identify low-gliadin wheat lines.
Prostate Cancer Surgery Improved
Researchers at UT Southwestern Medical Center have determined that light reflectance spectroscopy can differentiate between malignant and benign prostate tissue with 85 percent accuracy, a finding that may lead to real-time tissue analysis during prostate cancer surgery.
Faster UVA Molecular Analysis Technology
There are people in the world – chemical engineers, astronomers, national defense scientists investigating an explosion – who need to know just what something is made of, down to the molecular level.
Properties of Light Can be Controlled by Nanostructures
A study led by the UPV/EHU-University of the Basque Country professor Ángel Rubio has simulated a new device to generate terahertz radiation using carbon nanostructures.
Infrared Spectrometer ‘Engine’ for Developers
Si-Ware Systems has launched volume production of the smallest, lowest-cost infra-red spectrometer “engine” for developers.
Breaking the Chain
Compound prevents multidrug-resistant fungi from pumping out drugs.
Business News
Gold Nanoparticles Hold Promise for the Early Detection of Disease
Colloidal gold nanoparticles have been found to strongly enhance the native signals of chemical constituents in cells.
FACSS Charles Mann Award for Applied Raman Spectroscopy
Company has announced that its CEO Brian Marquardt will be honored with the Charles Mann Award for his work in the advancement of applied Raman spectroscopy technology.
Bruker Reports First Quarter 2016 Financial Results
Bruker Corporation reported financial results for its first quarter ended March 31, 2016.
Rock River Lab Opens NY Lab
Rock River Laboratory has opened the doors to a new feed and forage analysis laboratory in Binghamton, N.Y.
Pittcon 2016 in Atlanta, Another Success Story
Pittcon 2016, the 67th Conference and Exposition for Analytical Chemistry and Applied Spectroscopy, ended with an economic impact to the city estimated at $25.8 million.
Metrohm USA Extends Young Chemist Award to Honor Top 5 Submissions
The Young Chemist Award is open to all graduate, post-graduate and doctorate students residing and studying in the U.S. and Canada, who are performing novel research in the fields of titration, ion chromatography, spectroscopy and electrochemistry.
Shimadzu, University of Wisconsin-Milwaukee Partner
Company has announced it has opened Shimadzu Laboratory for advanced applied and analytical chemistry at the University of Wisconsin-Milwaukee.
Inside Raman 2016 is to be held at the Renishaw Innovation Centre
Renishaw's Raman spectroscopy team will be hosting its next Inside Raman UK event on 19th April 2016. It will be held, for the very first time, at Renishaw's New Mills headquarters in Gloucestershire.
Magritek Benchtop Spinsolve Used to Teach Students How to Apply NMR for Spectroscopic Characterization
Magritek report on the use of their Spinsolve Benchtop NMR spectrometer in the practical teaching of organic chemistry students at Tarrant County College in Fort Worth, Texas.
Multi-Mode Microplate Reader Trends
In this article we explore end-user opinion of some the new features available on MM plate readers and their potential influence on purchasing decision for a new MM plate reader.

Events
5th Zing Coordination Chemistr
17 Jun 2016
5th Zing Coordination Chemistr ...
WWEM - Water, Wastewater & Env
02 Nov 2016
WWEM - Water, Wastewater & Env ...

ePosters
CRISPR-Cas9 genome editing utilizing chemically synthesized RNA
Dharmacon (part of GE Healthcare)

CRISPR-Cas9 gene editing using synthetic crRNA:tracrRNA or sgRNA is highly efficient and easy to use. Synthetic crRNA:tracrRNA is uniquely suited to in vitro and in vivo applications, in particular, DNA-free approach with Cas9 mRNA. Chemical synthesis of guide RNAs allows accurate and rapid production of arrayed crRNA libraries for high-confidence, loss-of-function screens.
The Case for CASE: Computer-Assisted Structure Elucidation
ACD/Labs

Modern CASE systems such as Structure Elucidator Suite provide the necessary capability accurately elucidate a novel chemical structure for complex molecules based on readily available NMR data sets. This allows organizations to avoid expensive, labor-intensive, and time-consuming synthetic efforts.
A Unified Software Platform for Laboratory Informatics
Advanced Chemistry Development, Inc. (ACD/Labs), Toronto, Canada.

Reported here are capabilities in automated workflows involving analytical data with chemical structures. Specifically described is automated homogenization of data from a set of instruments, including NMR structure verification, as one solution.
Gene Expression Patterns in Donor-matched Mesenchymal Stem Cells and Osteocytes from Human Trabecular Bone
Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, UK

The study aimed to investigate gene expression profiles of osteocytes in healthy and OA bone and to compare with donor - matched MSCs.
Rapid electrochemical impedance spectroscopy for protein detection in Lab-on-a-Chip devices
(a) Thomas Johann Seebeck Department of Electronics, Tallinn University of Technology, Tallinn, Estonia; (b) Protobios OÜ, Tallinn, Estonia

We present results in rapid solution impedance spectroscopy to detect protein interactions (antibody-antigen) in human serum. Two different serum-antibody mixtures are measured in cuvettes, interfaced with screen-printed electrodes to determine whether the experimental setup can detect differences in composition.
Advanced Microfluidic Mixing Device for the Study of Macromolecule Dynamics
Department of Biomedical, IIT Hyderabad

We have developed and characterized a micro-fluidic mixer to study the macro-molecule dynamics such as kinetics of protein folding, DNA sequencing, single molecule study and detection etc. on a micro-second timescale. Numerical simulation has been performed to analyse the study of mixing performance of micro-fluidics channel.
Analysis of Terpenes Using Gas Chromatography with Vacuum Ultraviolet
The University of Texas at Arlington and VUV Analytics

The VUV absorption spectra for different terpenes were distinctive and differentiable. GC-VUV demonstrated the capabilities for qualitative and quantitative analysis of terpenes in turpertine mixtures. Chromatographic coeluting signals can be deconvolved by the VUV data analysis software.

Assessing Diversity in Cassava through the Application of Metabolomics
aSchool of Biological Sciences, Royal Holloway University of London, Egham, UK bInternational Center for Tropical Agriculture, CIAT

In the present study metabolomic platforms have been established for Cassava and used to assess the biodiversity present in Cassava germplasm collections and elucidate underlying biochemical mechanisms associated with traits of interest.
Metabolic response to everolimus in patient-derived xenografts of triple negative breast cancer
1Department of Circulation and Medical Imaging, The Norwegian University of Science and Technology, Trondheim, Norway, 2Department of Medical Imaging, St Olavs University Hospit

Everolimus treatment metabolic effects on TNBC PDX models were investigated using MR spectroscopy. PLS-DA successfully discriminated treated from controls and PDX expressing INPP4B and not. LMM revealed significant differences in 4/17 metabolites and two metabolite ratios between treated and controls.
Design considerations for highly specific and efficient synthetic crRNA molecules
GE Healthcare Dharmacon, Inc.

An overview of our rational design algorithm for picking highly functional crRNA sequences in combination with comprehensive specificity analysis.
Application Notes
Discriminating Between Polymorphs Of Acetaminophen Using Morphologically-Directed Raman Spectroscopy (MDRS)
Malvern Instruments Limited


Characterization of Protein Aggregates in Suspension and on a Filter Membrane by Morphologically-Directed Raman Spectroscopy
Malvern Instruments Limited


Aseptic Identification of Polysorbates using Handheld Raman
Rigaku Raman Technologies

As polysorbates are reactive to light and air, packaging is usually in thick, dark, amber bottles. This makes the identification process more difficult, as opening the container could compromise the sterility and quality of these materials. Handheld Raman is capable of identifying these materials without any sampling or preparation.
Herbal Materials and Natural Foods Analysis with Handheld Raman
Rigaku Raman Technologies

Dietary supplement manufacturers are required to use at least one appropriate test method to verify the identity of any component or excipient that is used in the manufacturing of a dietary supplement, as well as confirmation of identity of the product.
Cell Culture Media Identification In Biopharmaceuticals With Handheld Raman
Rigaku Raman Technologies

This application note discusses the identification of cell culture media using Raman analysis.
Drug Product Identification Using Handheld Raman
Rigaku Raman Technologies

Handheld Raman spectroscopy is well accepted as a technique for raw material and excipient identification within the pharmaceutical industry. Using the correct Raman excitation wavelength can extend its capabilities into the areas of drug substance and drug product identification.
Pharmaceutical Excipients Identification With Handheld Raman
Rigaku Raman Technologies

This application note discusses the identification of pharmaceutical excipients using Raman analysis.
Rapid Detection of Counterfeit and Substandard Medicines with Handheld Raman
Rigaku Raman Technologies

This application note discusses counterfeit screening using Raman analysis.
Forensic Analysis of an Artificial Sweetener Commonly Employed in Hoax Powder Attacks using Morphologically Directed Raman Spectroscopy
Malvern Instruments Limited

This application note details how Morphologically Directed Raman Spectroscopy (MDRS) using the Morphologi G3-ID can be applied to the forensic identification of commercially sourced white powders commonly used in hoax powder attacks.
Pharmaceutical Excipient Characterization
Malvern Instruments Limited


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