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Biochrom Libra S50 UV/Vis Spectrophotometer

Webcasts
Webcast - Multi-site LIMS HarmonizationMulti-site LIMS Harmonization
This webinar will explore the process for capturing current state workflows and projecting future state improvements and harmonization across distributed locations and work groups.
Webcast - Imaging Biomarkers - Future or RealityImaging Biomarkers - Future or Reality
Edwin van Beek, University of Edinburgh, speaking at Diagnostics & Biomarkers 2015.

Market Reports
Single Cell Omics 2011
Select Biosciences Ltd

The single cell Omics revolution is the potential transformation of cellular heterogeneity from a source of noise to a source of new, as yet hidden discoveries.
Scientific News
Hunting the Missing Link Between Genetics and the Environment
The International Phenome Centre Network (IPCN) works to transform healthcare through phenomics - the dynamic interactions between our genes and our environment.
Chemical Snapshots Could Lead to Better Engineered Cartilage
Taking "chemical photographs" of the cartilage between joints and comparing it to engineered versions could lead to better implants, say researchers.
Identifying Functional Biomarkers of Traumatic Brain Injury
In this study, prefrontal hemodynamic biomarkers were identified that can distinguish traumatic brain injury patients from healthy subjects.
Peer Review is in Crisis, But Should be Fixed, Not Abolished
After the time to get the science done, peer review has become the slowest step in the process of sharing studies, and some scientists have had enough.
Identification of Individual Red Blood Cells by Raman Microspectroscopy
In this study, Raman Microspectroscopy was used to identify individual red blood cells.
The Power Of Orthogonality In Assessing The Stability Of Biopharmaceuticals
By utilizing orthogonal techniques, researchers can maximize the secure application of all analytical results generated.
3D-Printing in Science: Conference Co-Staged with LABVOLUTION
LABVOLUTION 2017 will have an added highlight of a simultaneous conference, "3D-Printing in Science".
Curcumin Shows Promise as Cancer Treatment
When delivered at the correct circadian phase, curcumin demonstrates sustained toxicity in cancer cells and should be considered for use in patient care.
Using the Linkam THMS600 Temperature Stage to Study Fluid Inclusions
The University of Lyon use the Linkam THMS600 temperature stage for the study of Brillouin spectroscopy of fluid inclusions.
Guided Needles Hit the Mark
New sensor could help anesthesiologists place needles for epidurals and other medical procedures.
Business News
Eppendorf Acquires Calibration Technology
Acquisition will allow Eppendorf to expand it's service presence into Ireland.
smartLAB 2017: For Tomorrow’s Intelligent Laboratories
smartLAB 2017 will be held 16-18 May at LABVOLUTION along side BIOTECHNICA life sciences show.
DeNovix Receives Patent for Innovations In Microvolume UV-Vis
The DS-11 FX Series of Spectrophotometers / Fluorometers from DeNovix has been granted patent US 9,442,009 for its engineered solutions for improving the accuracy of microvolume UV-Vis spectrophotometry.
Ellutia Agrees New Strategic Alliance with Prism Analytical
The alliance calls for innovative solutions in chromatography technology.
Analytik Jena, Fresenius University Partner
With the new application center, Company is responding to growing demand for consulting, seminar, and training opportunities in the Frankfurt am Main economic region.
MarqMetrix, Metrohm Partner to Improve Raman Spectroscopy
MarqMetrix has developed the only TouchRaman spectroscopy measurement device and is partnering with Metrohm USA, a leading provider of laboratory and process instrumentation, to make Raman spectroscopy more accessible, accurate and reliable.
MarqMetrix® Hellma Partner to Bring Raman Spectroscopy to the Classroom
The new technology will be on display during SCIX 2016.
BMG LABTECH Invests 4.5 Million Euro in Headquarters Site Expansion
Leading microplate reader manufacturer doubles its production area.
Overcoming the Challenges of KF Analysis
Metrohm USA is pleased to announce a series of seminars dedicated to Karl Fischer (KF) analysis hosted in 16 cities across the US and Canada.
BioTek Instruments' Site Expansion
BioTek announces the beginning of an expansion project with a 22,000 square foot facility.

Events
Pittcon 2017
05 Mar 2017
Pittcon 2017 ...
Arablab 2017
20 Mar 2017
Arablab 2017 ...
15th International Scientific
06 Apr 2017
15th International Scientific ...

ePosters
Functional Analysis of RAD51B and RAD23B SNPs using Circular Chromosome Conformation Capture (4C) in Human Prostate Cell Lines
[sup}1.[/sup} The Institute of Cancer Research, 123 Old Brompton Road, London, UK 2.The Royal Marsden NHS Foundation Trust, Fulham Road, London, UK

The aim of this study is to understand the mechanism behind the association between single nucleotide polymorphisms (SNPs), lying in non-coding regions near or within RAD51B and RAD23B, and prostate cancer risk by analysing their interactions with the whole genome using Circular Chromosome Conformation Capture (4C).
CRISPR-Cas9 genome editing utilizing chemically synthesized RNA
GE Healthcare Dharmacon, Inc.

Chemical synthesis has been easily applied for rapidly generating either crRNA and tracrRNA or synthetic sgRNA for direct delivery into cells for gene editing applications such as DNA-free options and high throughput arrayed screening.
The Chemical Synthesis of Long and Highly Modified RNA using 2'-ACE Chemistry
GE Healthcare Dharmacon, Inc.

Dharmacon has previously developed a novel RNA synthesis chemistry making RNA synthesis as reliable, accessible and of comparable quality as routinely observed in DNA synthesis.
Blood Transcriptomic Diagnosis of Active TB with Five Genes
1Infection & Immunity, University College London, UK 2Department of Microbiology, University College London Hospitals NHS Trust, UK 3Blizard Institute, Queen Mary Univ

This study aimed to identify the minimal set of genes that can accurately diagnose active TB, both pulmonary and extrapulmonary, and evaluate their specificity.
Experimental design considerations for efficient and specific gene knockin using a CRISPR-Cas9 for HDR with synthetic crRNA and tracrRNA
Dharmacon, part of GE Healthcare

Precise genome engineering with CRISPR-Cas9 and single-stranded DNA oligo or double-stranded DNA plasmid donors via homology-directed repair (HDR).
Super-resolution single molecule localization microscopy of the exocytotic machinery underlying insulin secretion.
Heriot-Watt Univeristy

Single molecule imaging of the tSNARE proteins involved in insulin secretion.
Resistance-Associated Variants in HCV Genotype 1 Populations
1Vela Diagnostics Pte. Ltd., Singapore; 2Molecular Diagnosis Centre, Department of Laboratory Medicine, National University Hospital, Singapore; 3Department of Patholo

In this study we specifically investigated RAVs emerging in HCV genotype 1.
Integrated Next-Generation Sequencing and qPCR Workflow in Clinical Diagnostics
Vela Diagnostics Pte. Ltd., Singapore

Combined automated qPCR and NGS Sentosa workflow is a reliable and efficient in vitro diagnostics (IVD) tool for the detection and/or quantitation of a wide range of bacterial and viral pathogens as well as gene mutations.
A Synthetic CRISPR-Cas9 System for Homology-directed Repair
Dharmacon (part of GE Healthcare)

Synthetic, dual-RNA-encoded Cas9 is used for precise homology-directed repair (HDR) gene engineering. Both short and long (GFP) inserts are covered.
CRISPR-Cas9 genome editing utilizing chemically synthesized RNA
Dharmacon (part of GE Healthcare)

CRISPR-Cas9 gene editing using synthetic crRNA:tracrRNA or sgRNA is highly efficient and easy to use. Synthetic crRNA:tracrRNA is uniquely suited to in vitro and in vivo applications, in particular, DNA-free approach with Cas9 mRNA. Chemical synthesis of guide RNAs allows accurate and rapid production of arrayed crRNA libraries for high-confidence, loss-of-function screens.
Application Notes
Investigating the Effects of Excipients on the Earliest Stages of Aggregation - Aggregation Inhibition by Arginine
Malvern Instruments Limited

Use of static and dynamic light scattering to characterize the stability of lysozyme in the presence and absence of arginine. SLS is used to assess aggregation temperature, while DLS is used to measure the various particle sizes present in the two formulations at different temperatures, and measurements of zeta potential are used to assess the effect of arginine on the charge state of the protein.
Discriminating Between Polymorphs Of Acetaminophen Using Morphologically-Directed Raman Spectroscopy (MDRS)
Malvern Instruments Limited


Characterization of Protein Aggregates in Suspension and on a Filter Membrane by Morphologically-Directed Raman Spectroscopy
Malvern Instruments Limited


Aseptic Identification of Polysorbates using Handheld Raman
Rigaku Raman Technologies

As polysorbates are reactive to light and air, packaging is usually in thick, dark, amber bottles. This makes the identification process more difficult, as opening the container could compromise the sterility and quality of these materials. Handheld Raman is capable of identifying these materials without any sampling or preparation.
Herbal Materials and Natural Foods Analysis with Handheld Raman
Rigaku Raman Technologies

Dietary supplement manufacturers are required to use at least one appropriate test method to verify the identity of any component or excipient that is used in the manufacturing of a dietary supplement, as well as confirmation of identity of the product.
Cell Culture Media Identification In Biopharmaceuticals With Handheld Raman
Rigaku Raman Technologies

This application note discusses the identification of cell culture media using Raman analysis.
Drug Product Identification Using Handheld Raman
Rigaku Raman Technologies

Handheld Raman spectroscopy is well accepted as a technique for raw material and excipient identification within the pharmaceutical industry. Using the correct Raman excitation wavelength can extend its capabilities into the areas of drug substance and drug product identification.
Pharmaceutical Excipients Identification With Handheld Raman
Rigaku Raman Technologies

This application note discusses the identification of pharmaceutical excipients using Raman analysis.
Rapid Detection of Counterfeit and Substandard Medicines with Handheld Raman
Rigaku Raman Technologies

This application note discusses counterfeit screening using Raman analysis.
Forensic Analysis of an Artificial Sweetener Commonly Employed in Hoax Powder Attacks using Morphologically Directed Raman Spectroscopy
Malvern Instruments Limited

This application note details how Morphologically Directed Raman Spectroscopy (MDRS) using the Morphologi G3-ID can be applied to the forensic identification of commercially sourced white powders commonly used in hoax powder attacks.
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