Corporate Banner
Satellite Banner
Spectroscopy
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Conformetrix and AstraZeneca Sign Collaborative Agreement

Published: Thursday, April 26, 2012
Last Updated: Thursday, April 26, 2012
Bookmark and Share
First collaborative deal for Conformetrix.

Conformetrix Ltd and AstraZeneca have announced that they have signed a research collaboration agreement under which Conformetrix's proprietary NMR-based technology will be applied across AstraZeneca's pre-clinical therapeutic pipeline to enhance lead discovery and hit identification.

Conformetrix's technology determines accurate three-dimensional structures - or conformations - of drug molecules in their bioactive states.

This is achieved without the need for traditional structural information regarding the protein target of each drug and provides researchers with valuable information on how development-stage compounds are likely to interact with their targets.

This new information should improve the efficiency and quality of the lead identification, lead optimization and candidate selection stages of drug discovery programmes.

Under the terms of the two-year collaboration, the technology will also be used to determine the bioactive conformations of naturally occurring ligands as templates for drug library enhancement and hit identification.

Commenting on today's news, Conformetrix's CEO, Dr Sam Williams, said, 'Conformetrix is delighted that its first collaborative deal is with AstraZeneca, a company with a strong reputation in innovative science-led R&D. We believe that this deal provides important validation of our technology, which improves the quality and efficiency of drug discovery, reducing the number of molecules needed to find a drug and enhancing the likelihood of clinical success. The Conformetrix team is looking forward to working with our new partner on this exciting programme.'

Mike Snowden, Vice President and Head of Discovery Sciences, AstraZeneca, said: "We are excited to be working with Conformetrix. We believe their technology will provide a powerful addition to our hit identification and lead optimization approaches, supporting our strategic objectives to improve the quality and choice of candidate compounds for our early pipeline."

In addition to an undisclosed upfront payment, Conformetrix will receive research funding and be eligible for milestones as certain targets are met. The discovery programme will be managed by a joint AstraZeneca-Conformetrix research team.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,200+ scientific posters on ePosters
  • More than 4,800+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
Improving Wheat Crops in the Field
Agrii, RAGT and the University of Nottingham are developing better disease management and yield production in wheat crops using ASD FieldSpec Handheld 2 portable spectroradiometers.
Monitoring Changes, Variability in Blood
Raman spectroscopy used as a tool for monitoring biochemical changes and inter-donor variability in stored red blood cell units.
University Uses Magritek Benchtop NMR to Teach Organic Chemistry
Magritek reports on the benefits of their Spinsolve Benchtop NMR spectrometer for teaching practical organic chemistry to undergraduate students at Cleveland State University in Ohio.
Tracking The Aluminum Used To Purify Tap Water
Kobe University researchers demonstrate a new analysis method to measure the concentration of aluminium used to purify tap water.
New Imaging Method Reveals Nanoscale Details about DNA
Enhancement to super-resolution microscopy shows orientation of individual molecules, providing a new window into DNA’s structure and dynamics.
Scientific Gains May Make Electronic Nose the Next Everyday Device
UT Dallas team breathes new life into possibilities by using CMOS integrated circuits technology.
What Makes a Good Scientist?
It’s the journey, not just the destination that counts as a scientist when conducting research.
Copper is Key in Burning Fat
Berkeley Lab scientist says results could provide new target for obesity research.
Unveiling the Complexity of Mysterious Protein Folding
Imagine trying to reverse engineer a car when all you have is a finished product or a box full of parts — no instructions.
New System for Detecting Explosives
Spectroscopic system with chip-scale lasers cuts detection time from minutes to microseconds.
Skyscraper Banner

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,200+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,800+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!