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Cardiac iPSCs for Drug Discovery...
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NutriStem® hPSC XF Medium A Superior Xeno-free, Serum-free Culture Medium for hES and hiPS Cells
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Celigo S Cell Imaging Cytometer

Webcasts
The Tip of the Iceberg - How Pipette Tips Influence Assay Results
n this webinar, you will learn everything you need to know about pipette tips and the huge impact they can have on your results.
Subcellular fractionation and enrichment strategies for improved mass spectrometry analysis
In this webinar, you will learn how differential detergent subcellular fractionation can improve protein identification and be used to identify co-localizing proteins.

Market Reports
Circulating Tumor Cells (CTCs) and Cancer Stem Cells (CSCs) Market Report 2013
Select Biosciences Ltd

This is the latest and most up-to-date Market Report from Select Biosciences addressing the CTC and CSC markets as they are evolving rapidly.
Cellular Therapy and Cord Blood 2013 Market Report
Select Biosciences Ltd

This is the most up-to-date market report focusing on Cellular Therapy and the HSCT/Cord Blood Market Landscape, published by Select Biosciences.
Circulating Tumor Cells (CTCs) and Cancer Stem Cells (CSCs) Market Report 2012
Select Biosciences Ltd

In this report, we focus upon the biology of CTCs and CSCs as well as explore the inter-relationship between these cell types based upon molecular events. Also presented are research trends which are for the isolation and study of CTCs, a potentially important tool for cancer diagnostics with special relevance to cancer metastatic mechanisms.
Circulating Tumor Cells (CTCs) Market Trends 2011
Select Biosciences Ltd

This is the latest and most up-to-date Market Report from Select Biosciences addressing the circulating tumor cells (CTCs) space. In this report, we focus upon the emerging marketplace for the isolation and study of CTCs, a potentially important tool for cancer diagnostics with special relevance to cancer metastasis and mechanisms thereof.
Umbilical Cord Blood Banking Market Trends 2011
Select Biosciences Ltd

This report focuses upon cord blood banking and provided quantitative market analysis of the space as it relates to the growth of the field, utilization trends of cord blood for different diseases in different countries of the world.
Single Cell Omics 2011
Select Biosciences Ltd

The single cell Omics revolution is the potential transformation of cellular heterogeneity from a source of noise to a source of new, as yet hidden discoveries.
Future Directions in Regenerative Medicine
Business Insights

This report covers the development of therapies to replace human cells or promote their regeneration: including cell therapies, tissue engineering, drugs, and medical devices. Each company profiled has at least one project in preclinical or Phase I study. Many also have later stage or launched products, which are covered briefly to illustrate the potential of the next generation of candidates.
Innovations in Combating Infectious Diseases: Opportunities in therapeutics and diagnostics through application of proteomics, genomics, nanotechnology, and novel sources of lead generation
Business Insights

This report makes a detailed and comprehensive analysis of the cutting edge of research aiming to reveal how bacteria, viruses, fungi, and prions infect and affect their hosts. It also assesses the new technologies and techniques that are being used to design and develop the anti-infective drugs and diagnostic methods of the 21st century.
Stem Cells for Cellular Therapy 2010 Market Report
Select Biosciences Ltd

This market report is focused on presenting the market characteristics of stem cells as they are currently impacting research in the cellular therapy space. Furthermore, this report also addresses an important market, namely that of Umbilical Cord Blood Banking.
Adult Stem Cells Market Trends 2011
Select Biosciences Ltd

This report is focussed upon adult stem cells (especially mesenchymal stem cells; MSCs) and their properties making them highly suited for the development of cellular therapeutics.
Scientific News
Featured Article
Stem Cells in Drug Discovery
Potential Source of Unlimited Human Test Cells, but Roadblocks Remain.

Genetics Control Regenerative Properties Of Stem Cells
Researchers define how genetic factors control regenerative properties of blood-forming stem cells.
Allen Institute Releases Gene Edited Human Stem Cell Lines
The Allen Cell Collection, a publicly available collection of gene edited pluripotent stem cells, has been made available by the Allen Institute.
Designer Cell Fate Switches Could Streamline Stem Cell Biology
Researchers develop new method of reprogramming cells between cell types in a more efficient way than before.
Improving Drug Production with Computer Model
A model has been developed that can be used to improve and accelerate the production of biotherapeutics, cancer drugs, and vaccines.
Defining the Immortality of Stem Cells
Researchers defined the mechanisms underlying increased protein quality control of pluripotent stem cells.
BioCision Forms MedCision
The new company will focus on technologies for the management and automation of vital clinical processes.
Enhancing CRISPR to Explore Further
Researchers have developed sOPTiKO, a more efficient and controllable CRISPR genome editing platform.
Stem Cells Police Themselves to Reduce Scarring
Scientists have discovered stem cells in muscle fibers change gene expressions to respond to injury.
Regenerating Diseased Hearts
Researchers from the University of Otago have probed the potential of adult stem cell types to repair diseased hearts.
Business News
2017 Breakthrough Prize in Life Sciences
The recipients of the 2017 Breakthrough Prizes were announced, with $15M in life science awards.
Thermo Fisher Scientific Acquires MTI-GlobalStem
Thermo expands transfection and stem cell research arm by acquiring MTI-GlobalStem, specialists in cell transfection, neurobiology and stem cell research applications.
Chan Soon-Shiong Biobank at Windber Receives CLIA Certification
The Chan Soon-Shiong Biobank at Windber has been certified by the U.S. Department of Health under the CLIA.
Thermo Fisher Acquires MTI-GlobalStem
The technology strengthens Thermo Fisher’s leadership in biosciences and provides scientists around the world with access to a wider array of advanced research products designed to help accelerate discovery using cell models.
Oxford BioMedica, Orchard Therapeutics Announce Alliance
The alliance will develop and supply lentiviral vectors used by Orchard for the manufacture of ex-vivo gene therapy products.
Bayer, AHA Cardiovascular Collaboration
Bayer and the American Heart Association collaborate to advance cardiovascular research in areas of unmet medical need.
Axiogenesis, Metrion Biosciences Collaborate
Collaboration aims to develop human induced pluripotent stem cell (iPSC)-derived cardiomyocytes and neurons for use in translational drug discovery.
Eppendorf Acquires Calibration Technology
Acquisition will allow Eppendorf to expand it's service presence into Ireland.
Plasticell Completes £1.32 Million Financing to Advance Therapeutic Projects
Plasticell announces the completion of a two-part equity financing round, raising a total of £1.32 million from its shareholders and new investors.
Adaptimmune, MSD Collaborate
Adaptimmune announces collaboration with MSD to evaluate KEYTRUDA® (pembrolizumab) in combination with NY-ESO SPEAR® T-Cell therapy in multiple myeloma.

Events
13th Annual Cell & Gene Therap
17 Jan 2017
13th Annual Cell & Gene Therap ...
Innovations in wound healing a
31 Jan 2017
Innovations in wound healing a ...
SLAS2017
04 Feb 2017
SLAS2017 ...
Challenges, Solutions and Prog
18 Feb 2017
Challenges, Solutions and Prog ...

ePosters
Building and deploying digital pathology infrastructure for a heterogeneous user base
Faculty of Medicine, Vrije Universiteit Brussel; University Hospital Brussels (UZ Brussel):

Too often, image analysis and data/image mining projects remain stuck in
microenvironments because they are limited by vendorspecific
solutions that neither scale nor interact with material from other departments or institutions. Successful rollout of digital histopathology therefore requires more than a whole slide scanner. At Brussels Free
University (VUB), we wanted to provide a core digital pathology infrastructure that can support a range of different use cases.
Microfluidic extrusion of cell-laden hydrogel fibers for 3D-Bioprinting
CLNS - iit@Sapienza - Viale Regina Elena 291 - 00161 - Roma

An overview on how the incorporation of microfluidic platforms in 3D-bioprinters can open new routes in the creation of heterogeneous, tissue-specific bio-constructs and in the high-throughput screening of bioinks compositions for regenerative medicine and in vitro tissue modeling.
Use of non-modified RNAs for the derivation of clinically-relevant iPS cell lines from human blood, urine and skin cells using GMP-compliant reagents
Stemgent, Lexington, MA, USA; Translational Oncology at Univ Medical Center, Mainz, Germany, BioNTech RNA Pharmaceuticals GmbH, Mainz, Germany; Division of Respiratory Medicine, University of Cambrid

We have developed protocols using our StemRNA-NM Reprogramming Kit for generating iPS cells from skin-derived fibroblasts, blood-derived EPCs, and urine-derived UDCs using GMP-compatible reagents (NutriStem medium, iMatrix-511 recombinant laminin). These protocols generate GMP-compatible stem cells without the use of feeders, conditioned medium, additional small molecules or proteins, or passaging during reprogramming.
A Novel Set of Serum-Free, Xeno-Free Differentiation Media for Adipogenesis, Osteogenesis and Chondrogenesis of Human Mesenchymal Stem Cells from Various Tissue Sources
Biological Industries

An overview of a novel SF, XF differentiation system which enables achieving defined conditions for rapid generation of differentiated hMSCs towards tissue engineering and drug screening applications.
A Novel Set of Serum-Free, Xeno-Free Differentiation Media for Adipogenesis, Osteogenesis and Chondrogenesis of Human Mesenchymal Stem Cells from Various Tissue Sources
Biological Industries

An overview of a novel SF, XF differentiation system which enables achieving defined conditions for rapid generation of differentiated hMSCs towards tissue engineering and drug screening applications
Pharmacological Responses in Cultured Human iPSC-Derived Cortical Neurons Using Multi-Electrode Array
(1) Department of Electronics and Intelligent Systems, Tohoku Institute of Technology, Sendai, Miyagi, Japan; (2) Japan Society for the Promotion of Science, Tokyo, Japan; (3) Axol Bioscience Ltd., Ca

The functional network of human induced pluripotent stem cell (hiPSC)-derived neurons is a potentially powerful in vitro model for evaluating disease mechanisms and drug responses. However, the culture time required for the full functional maturation of individual neurons and networks is uncertain. We investigated the development of spontaneous electrophysiological activity and pharmacological responses for over 1 year in culture using multi-electrode arrays (MEAs).
Translational Research of oral Neural Crest-Derived Stem Cells (oNCSCs) in Regenerative Dentistry
1Stavropol State Medical University, Russian Federation, 2Praxisteam Hasslinghausen, Germany, 3Implantology Center Kassel, Germany, 4Witten/ Herdecke University, Germany, 5University of Reading, UK, 6

In this review poster, we summarize current knowledge on the oral neural crest-derived stem cell populations (oNCSCs) and discuss their potential in regenerative periodontology as a part of regenerative dentistry.
Different Pathways of Regenerative Medicine
TRM Leipzig, Universität Bielefeld

Altough regenerative medicine is rapidly developing there is neither a technical definition nor a common use in practice. The aim of this study is to draw the line at the limits of regeneration and medicine in order to figure out a proper understanding of regenerative medicine. Furthermore, the analysis reveals a prospering future. It has shown that regenerative medicine technologies are used for a variety of therapeutic applications.
Building a digital pathology ecosystem for education and research
Department of Pathology, Faculty of Medicine, Vrije Universiteit Brussel; Department of Pathology, University Hospital Brussels

We wanted to build a core digital pathology infrastructure to support different use cases. Various images platforms needed to be accessible through a single access point, and support different user profiles.
Design and Validation of Bioluminescent Assays for 3D Cell Culture Models Poster
Promega Corporation

Cells cultured in 3D model systems often acquire relatively large in vivo-like structures compared to the thickness of a 2D monolayer of cells grown on standard plastic plates.
Application Notes
A Novel Lipid Screening Platform that Provides a Complete Solution for Lipidomics Research
SCIEX

The Lipidyzer™ Platform, powered by Metabolon®.
Novel Chemical Standards Kits Enable Facile Lipid Quantitation
SCIEX

The Lipidyzer platform provides more accurate lipid analysis with less quantitative bias.
3D Cell Culture: mimicking real tissue
Tecan Group Ltd.

Technological advances in the last couple of years have enabled 3D scaffolds to be engineered that offer a real proxy for the in vivo environment which can be easily and routinely used in a cell culture laboratory. Alvetex Scaffold enables cells to develop natural, in vivo-like intercellular interactions, providing an ideal environment for real three-dimensional growth and nutrient exchange that is comparable to intra-capillary exchange in living tissues.
Optimized cell culture
Tecan Group Ltd.

Culturing of various stable cell lines, including bacterial, yeast, hybridoma, insect and mammalian lines, and stem cells, is an important task in the pharmaceutical industry. The cells need to be maintained and expanded for use in cell-based assays, such as siRNA screening, ADME and high content screening, as well as for clone selection.
Stem cell research: Creating blood for high throughput screening
Tecan Group Ltd.

Many different research fields, including investigation of early human development processes, disease research, drug discovery and cellular therapy applications, require appropriate in vitro models which can accurately mimic in vivo processes to provide biologically relevant results. Pluripotent stem cells (PSCs) offer a powerful system for creating in vitro models to address these questions.
Analyzing Biological Samples
Tecan

This technical note describes the capability of Tecan’s Infinite® 200 PRO multimode reader to regulate the CO2 partial pressure inside its measurement chamber.
Measurement of Proteasome Inhibition in Live Cells in Molecular Devices Microplate Fluorometers
Molecular Devices

The proteasome is a massive protein complex which can recognize and bind targeted proteins, and inject them into the central core where the proteins are successively degraded into short peptides. Whereas protein synthesis is well-understood after decades of study, major advances in our knowledge of protein degradation have occurred only in the last two decades.
Sample Reformatting and Sample Archiving
FluidX

Biobanking is becoming a central element in the study of patient genetic data and clinical application of genetic research. Until recently, collections of DNA samples have tended to be fairly small and localized with varied sample containers that were unsuitable for an increasing throughput and automated system use.
Reading Racked 2D-Coded Cryo Tubes directly from -80ºC Freezer
FluidX

With the storage of biological samples such as DNA, protein, blood fractions and viable cells becoming commonplace. The need to store them at lower temperatures has resulted in reading challenges for traditional rack readers.
Isolation and Characterization of Human Bone-Marrow-Derived Mesenchymal Stem Cells
Millipore

Mesenchymal stem cells derived from bone marrow have become an attractive model cell system for the in vitro and in vivo study of disease states such as osteoporosis, obesity, and arthritis. We have isolated mesenchymal stem cells (MSCs) from the bone marrow aspirate of a single human donor. Human bone-marrow-derived MSCs express the mesenchymal stem cell markers STR0-1, CD44, and CD90, and do not express hematopoietic markers CD14 and CD19. Human bone-marrow-derived MSCs can be expanded for 18
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