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Plasticell Delivers Differentiation Protocols to Stemnion, Inc.

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Plasticell, has announced the successful completion of a collaboration with Stemnion, Inc. (Pittsburgh, PA), a US biotechnology company focused on the applications of stem cells derived from human placentas.

Plasticell used its flagship technology CombiCult™ to discover multiple novel, serum-free protocols that direct the differentiation of Stemnion’s stem cells into hard-to-obtain lineages.

The protocols were ranked using Plasticell’s Ariadne™ bioinformatics software and subsequently validated by Stemnion scientists.

“Using CombiCult™’s combinatorial technology, we identified several differentiation protocols for our cells at a fraction of the time, resources and cost compared to conventional trial-and-error methods,” said Randall Rupp, Vice-President, Manufacturing and Development, Stemnion, Inc.

“This project once again demonstrates the flexibility and the power of CombiCult™ to push the differentiation of adult stem cells into various lineages,” said Dr. Lilian Hook, Director of Research at Plasticell.

Dr. Hook continued, “Stemnion provided us with a challenge that is typical of adult stem cell R&D programmes, however this project was particularly interesting on several fronts, including, for the first time, utilizing placenta-derived stem cells as the starting cell-type.”