Corporate Banner
Satellite Banner
Stem Cells, Cellular Therapy & Biobanking
>
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Precision StemCell's InVivo Stem Cell Reprogramming Procedure Shows Potential for Treating ALS

Published: Tuesday, July 31, 2012
Last Updated: Tuesday, July 31, 2012
Bookmark and Share
ALS-stricken NFL player and coach, the first patient to undergo new procedure for reprogramming adult stem cells, shows auspicious results.

Eight years ago, Frank Orgel, a former NFL football player and college coach, was diagnosed with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.

Orgel's quality of life declined to the point that he could not move his left arm or leg, walk or even stand on his own.

But, within a few days of undergoing a new stem cell reprogramming technique performed by Dr. Jason R. Williams at Precision StemCell (http://www.precisionstemcell.com), Orgel's constant muscle fasciculation (muscle twitching) lessened significantly.

Within weeks, he was able to walk in a pool of water and stand unassisted.

The technique performed on Orgel is InVivo reprogramming, which reprograms adult stem cells into neural stem cells.

The procedure involves harvesting adult stem cells from the patient's own fat, which Dr. Williams obtains via minimally invasive liposuction, and then using image-guided therapy to insert the stem cells into the patient's spine.

For three to five days after the procedure, Dr. Williams places the patient on an oral medication that, as laboratory research has shown, causes stem cells to reprogram, converting them into neural stem cells.

"We are the only facility in the United States performing the InVivo reprogramming procedure," said Dr. Williams. "Frank was the first patient in the world, that we are aware of, to have the procedure done."

Orgel attests to the efficacy of the new procedure. "My leg normally drags and would have to be moved for me, but now I'm able to move it myself," he stated. "I feel that this is definite improvement."

Dr. Williams, a radiologist who specializes in image-guided procedures, had already been performing magnetic resonance imaging (MRI), computed tomography (CT), ultrasound and fluoroscopy-guided stem cell injections for joint and orthopedic conditions.

"This new technique of InVivo reprogramming shows great promise for possibly repairing or regenerating nerve cells," he stated. "That means it may open up opportunities for treating several neural conditions such as spinal cord injury, stroke, Parkinson's and Alzheimer's disease."

"We are really excited that this technique can help increase the number of neural stem cells that are transferred back into the patient," continued Dr. Williams.

Dr. Williams continued, "We are hopeful that this will indeed help us heal or regrow nerve cells; however, it is still too soon to really know."


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,000+ scientific posters on ePosters
  • More than 4,500+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
Turning Skin Cells into Heart, Brain Cells
In a major breakthrough, scientists at the Gladstone Institutes transformed skin cells into heart cells and brain cells using a combination of chemicals.
Stem Cells Know How to Unwind
Research led by the Babraham Institute with collaborators in the UK, Canada and Japan has revealed a new understanding of how an open genome structure supports the long-term and unrestricted developmental potential in embryonic stem cells.
Growing Stem Cells More Safely
Nurturing stem cells atop a bed of mouse cells works well, but is a non-starter for transplants to patients – Brown University scientists are developing a synthetic bed instead.
Cell Transplant Treats Parkinson’s in Mice
A University of Wisconsin—Madison neuroscientist has inserted a genetic switch into nerve cells so a patient can alter their activity by taking designer drugs that would not affect any other cell.
Skin Cells Turned into Heart Cells and Brain Cells Using Drugs
In a scientific first, Gladstone researchers have used chemical drugs to convert skin cells into heart cells and brain cells, without adding any external genes.
Shape Of Tumor May Affect Whether Cells Can Metastasize
Illinois researchers found that the shape of a tumor may play a role in how cancer cells become primed to spread.
‘Mini-Brains’ to Study Zika
Novel tool expected to speed research on brain and drug development.
Cytokine Triggers Immune Response at Expense of Blood Renewal
Research highlights promise of Anti-IL-1 drugs to treat chronic inflammatory disease.
AstraZeneca to Sequence 2 Million Genomes in Search for New Drugs
Company launches integrated genomics approach which aims to transform drug discovery and development.
Improving Engineered T-Cell Cancer Treatment
Purdue University researchers may have figured out a way to call off a cancer cell assassin that sometimes goes rogue and assign it a larger tumor-specific "hit list."
SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,000+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,500+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!