Corporate Banner
Satellite Banner
Stem Cells, Cellular Therapy & Biobanking
>
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Precision StemCell's InVivo Stem Cell Reprogramming Procedure Shows Potential for Treating ALS

Published: Tuesday, July 31, 2012
Last Updated: Tuesday, July 31, 2012
Bookmark and Share
ALS-stricken NFL player and coach, the first patient to undergo new procedure for reprogramming adult stem cells, shows auspicious results.

Eight years ago, Frank Orgel, a former NFL football player and college coach, was diagnosed with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.

Orgel's quality of life declined to the point that he could not move his left arm or leg, walk or even stand on his own.

But, within a few days of undergoing a new stem cell reprogramming technique performed by Dr. Jason R. Williams at Precision StemCell (http://www.precisionstemcell.com), Orgel's constant muscle fasciculation (muscle twitching) lessened significantly.

Within weeks, he was able to walk in a pool of water and stand unassisted.

The technique performed on Orgel is InVivo reprogramming, which reprograms adult stem cells into neural stem cells.

The procedure involves harvesting adult stem cells from the patient's own fat, which Dr. Williams obtains via minimally invasive liposuction, and then using image-guided therapy to insert the stem cells into the patient's spine.

For three to five days after the procedure, Dr. Williams places the patient on an oral medication that, as laboratory research has shown, causes stem cells to reprogram, converting them into neural stem cells.

"We are the only facility in the United States performing the InVivo reprogramming procedure," said Dr. Williams. "Frank was the first patient in the world, that we are aware of, to have the procedure done."

Orgel attests to the efficacy of the new procedure. "My leg normally drags and would have to be moved for me, but now I'm able to move it myself," he stated. "I feel that this is definite improvement."

Dr. Williams, a radiologist who specializes in image-guided procedures, had already been performing magnetic resonance imaging (MRI), computed tomography (CT), ultrasound and fluoroscopy-guided stem cell injections for joint and orthopedic conditions.

"This new technique of InVivo reprogramming shows great promise for possibly repairing or regenerating nerve cells," he stated. "That means it may open up opportunities for treating several neural conditions such as spinal cord injury, stroke, Parkinson's and Alzheimer's disease."

"We are really excited that this technique can help increase the number of neural stem cells that are transferred back into the patient," continued Dr. Williams.

Dr. Williams continued, "We are hopeful that this will indeed help us heal or regrow nerve cells; however, it is still too soon to really know."


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,500+ scientific posters on ePosters
  • More than 5,000+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
Analysing 10,000 Cells Simultaneously
New techniquethat traps 10,000 cells on a single chip has potential for cancer screening for individuals.
Studies Explore Science of Cardiovascular Diseases
Two studies highlight how basic science research insights are key to future treatment breakthroughs.
Stem Cell ‘Heart Patch’ Almost Perfected
Scientists aiming to perfect and test 3D "heart patches" in animal model, last hurdle before human patients.
Stem Cells Growing 3D Lung-in-a-Dish
Researchers have created 3D lung-like tissue from lung-derived stem cells. The tissue can be used to study lung diseases.
MRI Guidance Aids Stem Cell Delivery
Scientists have delivered stem cells to the brain with unprecedented precision, infusing the cells under real-time MRI guidance.
Mechanisms of Parkinson’s Pathology
Defects that lead to cells’ failure to decommission faulty mitochondria cause nerve cells to die, triggering the symptoms of Parkinson’s disease.
Stem Cell Transplant Without Radiation or Chemotherapy
Researchers have successfully performed stem cell transplants without using radiation or chemotherapy.
Advanced Lymphoma in Remission After T-Cell Therapy
63% of trial participants who recieved two-drug combination chemo plus intermediate dose of engineered T cells went into complete remission.
Inherited Heart Condition Breakthrough
Using stem cells, scientists have created a specific heart condition model, yeilding insights into unexpected disease mechanisms.
Biobank Storage Time Affects Blood Test Results
Study finds storage time of blood samples at a biobank may affect test results as much as patient age.
Skyscraper Banner

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,000+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!