Corporate Banner
Satellite Banner
Stem Cells, Cellular Therapy & Biobanking
Scientific Community
Become a Member | Sign in
Home>News>This Article

SETsquared-supported Research to Improve Stem Cell Therapy Results

Published: Monday, August 27, 2012
Last Updated: Monday, August 27, 2012
Bookmark and Share
Promises better recovery from strokes, brain injuries and diseases such as Parkinson’s.

Collaboration between two universities in the USA and UK, supported by funding from the SETsquared Partnership, looks set to help improve the results of stem cell therapies for brain and spinal cord injuries, strokes and diseases such as Parkinson’s.

Researchers from the University of California, Irvine and the labs of Drs. Michael Hughes and Fatima Labeed at the Centre for Biomedical Engineering, University of Surrey have worked together on identifying the most effective stem cells, helping to increase the benefits from treatment.

The researchers met at a meeting in Bath organized by SETsquared.

Funding provided by SETsquared was used primarily for travel, and also to buy some supplies needed for the research work.

The funding was part of a £1.5m award from the Office of Science and Technology (OST) in April 2006 to create relationships of lasting value with commercial focus around the high-technology research and development clusters of Southern England with those in Southern California.

The programme provided a five times return on the investment made by government. This is just an additional outcome to emerge from a relationship seeded through the programme.

“Without the support and funding from SETsquared, this collaboration simply would not have happened,” said Lisa Flanagan, Ph.D., assistant professor at the Department of Neurology and Sue and Bill Gross Stem Cell Research Center, University of California, Irvine.

“This project is an excellent example of how a relatively small financial stimulus, combined with networking meetings, can make a massive difference to collaborative research,” said Graham Harrison, Partnership Director at SETsquared.

Stem cells hold the promise of improving how we can repair the body following injury and disease.

For the brain and spinal cord, stem cell therapy is undergoing clinical trials, but one of the limiting factors is that half or less of the stem cells used have a beneficial effect, and it is difficult to tell the cells apart and work out which ones are effective.

The research project addresses this issue by using the biophysical characteristics of stem cells to distinguish them.

The team used a technique called dielectrophoresis (DEP) to analyze stem cells, and discovered that cell membrane capacitance predicts the treatment potential of stem cells.

“While we had already started to use DEP, Drs. Hughes and Labeed showed us how to get more out of it, which was the real turning point for us,” says Flanagan. “Although there’s lots of work to do, our research is showing real promise.”

Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,800+ scientific posters on ePosters
  • More than 4,000+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Scientific News
Ancient Viral Molecules Essential for Human Development
Genetic material from ancient viral infections is critical to human development, according to researchers at the Stanford University School of Medicine.
CRI Identifies Emergency Blood-formation Response
Researchers report that when tissue damage occurs, an emergency blood-formation system activates.
New Way to Force Stem Cells to Become Bone Cells
Potential therapies based on this discovery could help people heal bone injuries or set hardware, such as replacement knees and hips.
Dead Bacteria to Kill Colorectal Cancer
Scientists from Nanyang Technological University (NTU Singapore) have successfully used dead bacteria to kill colorectal cancer cells.
Promise of Newborn Stem Cells to Revolutionize Clinical Practice
In this article Shweta Sharma, PhD, discusses the potential of an Umbilical Cord Blood bank as an untapped source of samples for research and clinical trials.
The Life Story of Stem Cells
A model analyses the development of stem cell numbers in the human body.
Novel Stem Cell Line Avoids Risk of Introducing Transplanted Tumors
Progenitor cells might eventually be used to repair or rebuild damaged or destroyed organs.
Advancing Genome Editing of Blood Stem Cells
Genome editing techniques for blood stem cells just got better, thanks to a team of researchers at USC and Sangamo BioSciences.
Molecule Proves Key to Brain Repair After Stroke
Scientists found that a molecule known as growth and differentiation factor 10 (GDF10) plays a key role in repair mechanisms following stroke.
Towards Patient-Specific Drug Screening
A new breakthrough by the 3D stem cell printing team at Heriot-Watt could pave the way to individually tailored drug testing regimes, both reducing the need for animal testing and ensuring that patients receive drugs which are most effective for their individual needs.
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,800+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,000+ scientific videos