Corporate Banner
Satellite Banner
Stem Cells, Cellular Therapy & Biobanking
>
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

PrecisionMed Inc. Launches Amyotrophic Lateral Sclerosis Cerebrospinal Fluid Registry

Published: Wednesday, August 29, 2012
Last Updated: Monday, September 10, 2012
Bookmark and Share
The PrecisionMed ALS Registry is expected to be of value for the discovery and/or validation of biomarkers for neurodegenerative disease.

PrecisionMed Inc. announces enrollment of the first donor into the PrecisionMed Amyotrophic Lateral Sclerosis (ALS) Registry. The PrecisionMed ALS Registry is a biological sample bank of DNA and longitudinal CSF, RNA, serum and plasma linked to clinical data utilizing PrecisionMed’s clinical data procurement and clinical sample management capabilities.

The PrecisionMed ALS Registry will enroll up to 2000 donors, with either sporadic or familial ALS. All donors will be recruited, evaluated, clinically studied, and sampled from up to 10 experienced investigative sites in the US. Key aspects of donors’ clinical status will be evaluated every four months with simultaneous biological sampling.

“PrecisionMed is dedicated to establishing cohorts of individuals for in-depth, longitudinal clinical and biological evaluation,” said John Flax, M.D., President and CEO of PrecisionMed. “In The ALS Registry, following establishment of baseline measures, the same validated measurements will be repeated every four months in order to quantify longitudinal changes, enabling correlation with biomarkers measured in corresponding samples. Accurate phenotyping is critical in relating changes in the clinical picture to alterations in molecular biomarkers. PrecisionMed has prior experience with longitudinal and single visit CSF banking projects in Alzheimer’s disease, mild cognitive impairment, schizophrenia, Parkinson’s disease, multiple sclerosis and 'True Normal' populations. These ongoing sample collections are an acknowledged, valuable source of highly annotated neuroscience samples, including CSF, to the research community worldwide.

“Prospective study of a large sample of individuals using the ALS Registry design will enable multiple pharmaceutical and academic researchers to study the progression of ALS, using a multiplicity of biomarkers. By integrating the laboratory and clinical data, it should be possible to obtain important information for drug discovery, disease diagnosis, prediction of response to treatments and disease prognosis. The track record of PrecisionMed in this kind of collection is excellent and bodes well that the data and samples will be of the highest quality.”

Longitudinal samples with matched clinical data, collected from the same donors every four months, are available to our clients. Custom requests for additional sample types, as well as more complex clinical, laboratory and/or radiographic evaluations within selected subpopulations will be entertained as the registry matures.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,000+ scientific posters on ePosters
  • More than 4,400+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
Cell Transplant Treats Parkinson’s in Mice
A University of Wisconsin—Madison neuroscientist has inserted a genetic switch into nerve cells so a patient can alter their activity by taking designer drugs that would not affect any other cell.
Skin Cells Turned into Heart Cells and Brain Cells Using Drugs
In a scientific first, Gladstone researchers have used chemical drugs to convert skin cells into heart cells and brain cells, without adding any external genes.
Shape Of Tumor May Affect Whether Cells Can Metastasize
Illinois researchers found that the shape of a tumor may play a role in how cancer cells become primed to spread.
‘Mini-Brains’ to Study Zika
Novel tool expected to speed research on brain and drug development.
Cytokine Triggers Immune Response at Expense of Blood Renewal
Research highlights promise of Anti-IL-1 drugs to treat chronic inflammatory disease.
AstraZeneca to Sequence 2 Million Genomes in Search for New Drugs
Company launches integrated genomics approach which aims to transform drug discovery and development.
Improving Engineered T-Cell Cancer Treatment
Purdue University researchers may have figured out a way to call off a cancer cell assassin that sometimes goes rogue and assign it a larger tumor-specific "hit list."
Micro Heart Muscle Created from Stem Cells
Researchers have designed a new way to create micro heart muscle from stem cells using a unique dog bone dish.
Immune Booster Tested in Advanced Merkel Cell Cancer
The immunotherapy drug produced durable responses in many patients.
Mutated Mitochondria Found in Stem Cells
Researchers find hidden genetic mutations in patient-derived stem cells which could ultimately undermine therapeutic benefit.
SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,000+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,400+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!