Corporate Banner
Satellite Banner
Stem Cells, Cellular Therapy & Biobanking
>
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

3D Biomatrix Announces Allowance of U.S. Patent

Published: Thursday, February 06, 2014
Last Updated: Thursday, February 06, 2014
Bookmark and Share
Cell culture technology uniquely addresses 3D spheroid and embryoid body growth challenges.

3D Biomatrix, Inc. announce the Notice of Allowance of its U.S. Patent for technology included in the Perfecta3D  Hanging Drop Plates, a novel platform that makes 3D spheroid and embryoid body growth, along with an array of co-cultures, simple and inexpensive to perform. The patent entitled “Hanging Drop Devices, Systems and/or Methods” covers several core technologies: 

• The development of a complete hanging drop system that allows the performance of cell analysis in individual hanging drops within a standard 96- or 384-well platform. 

• The specific design of the Perfecta3D Hanging Drop Plate, which allows the growth of one spheroid or embryoid body per well without adherence to a plastic surface or other substance. 

• The inclusion of a water or media reservoir that acts as a humidity source to alleviate the commonly-encountered hanging drop evaporation problem. 

Researchers have long tested drug compounds and other factors affecting cell growth on flat surfaces in two dimensions (2D), but 2D cell cultures do not accurately represent how cells behave in the three-dimensional body. 3D cell cultures grown in the Perfecta3D Hanging Drop Plates allow researchers to recapitulate these characteristics in vitro, providing a more physiologically-relevant model. 3D Biomatrix’s Hanging Drop Plates facilitate the consistent and controllable growth of small spherical cellular 3D clusters in a well-plate format, allowing researchers to test compounds and other factors in a 3D environment that reflects the human body. 

3D Biomatrix and the University of Michigan are listed as the assignees of the patent. 3D Biomatrix holds an exclusive license for worldwide rights to the intellectual property covered by this patent. The inventors of the Perfecta3D technology include Shuichi Takayama, a professor having a joint appointment in the Department of Biomedical Engineering and Macromolecular Science and Engineering at the University of Michigan, Yi-Chung Tung, Amy Yu-Ching Hsiao and Edward Jan. Dr. Takayama is a member of 3D Biomatrix’s Scientific Advisory Board. 

“The allowance of this patent is an important milestone, and we will continue to expand our IP portfolio. Life science and drug discovery researchers want more relevant tools in their toolbox. Although the hanging drop technology has been used for decades, the available techniques were difficult to use making it challenging to reproduce results consistently. The 96- and 384-well Perfecta3D Hanging Drop Plates make spheroid growth, long- and short-term cultures, and expansive co-culture models simple to perform and reproduce in 3D,” said 3D Biomatrix CEO Laura Schrader.

"Our worldwide customers include researchers in academia performing cell biology, cancer and stem cell research as well as leading pharmaceutical companies who want to reduce the drug attrition rate by getting more relevant answers earlier in their research process along with the ability to perform high-content analysis and high-throughput screening,” concluded Schrader.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,200+ scientific posters on ePosters
  • More than 4,700+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
A New Way Out for Stem Cells
Researchers at North Carolina State University have discovered that therapeutic stem cells exit the bloodstream in a different manner than was previously thought.
Manufactured Stem Cells To Advance Clinical Research
Clinical-grade cell line will enable development of new therapies and accelerate early-stage clinical research.
Starving Stem Cells May Enable Scientists To Build Better Blood Vessels
Researchers from the University of Illinois at Chicago College of Medicine have uncovered how changes in metabolism of human embryonic stem cells help coax them to mature into specific cell types — and may improve their function in engineered organs or tissues.
Long-Term Culturing of Adult Stem Cells
A new procedure developed by Harvard Stem Cell Institute researchers (HSCI) at Massachusetts General Hospital (MGH) may revolutionize the culturing of adult stem cells.
Naked Mole Rat Exhibits “Extraordinary” Cancer Resistance
Scientists are getting closer to understanding the anti-cancer mechanism of the naked mole rat by making induced pluripotent stem cells.
Solutions for Biotherapeutic Characterization
Innovation to speed the routine.
Reclaiming The Immune System's Assault On Tumors
EPFL study shows a way to reclaim corrupted immune cells.
What Makes a Good Scientist?
It’s the journey, not just the destination that counts as a scientist when conducting research.
Body’s Own Gene Editing System Generates Leukemia Stem Cells
Inhibiting the editing enzyme may provide a new therapeutic approach for blood cancers.
Cirrhosis-Causing Cells Converted to Healthy Liver Cells in Mice
New approach that repairs liver from within may be more efficient than cell transplants.
SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,200+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!