Corporate Banner
Satellite Banner
Stem Cells, Cellular Therapy & Biobanking
>
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Salk Institute and Stanford Lead New $40M Stem Cell Genomics Center

Published: Sunday, February 02, 2014
Last Updated: Friday, February 07, 2014
Bookmark and Share
Collaborative research center will bridge genomics and stem cell projects to find new therapies.

The Salk Institute for Biological Studies will join Stanford University in leading a new Center of Excellence in Stem Cell Genomics, created through a $40 million award by California's stem cell agency, the California Institute for Regenerative Medicine.

The center will bring together experts and investigators from seven major California institutions to focus on bridging the fields of genomics — the study of the complete genetic make-up of a cell or organism — with cutting-edge stem cell research.

The goal is to use these tools to gain a deeper understanding of the disease processes in cancer, diabetes, endocrine disorders, heart disease and mental health, and ultimately to find safer and more effective ways of using stem cells in medical research and therapy.

"The center will provide a platform for collaboration, allowing California's stem cell scientists and genomics researchers to bridge these two fields," says Joseph Ecker, a Salk professor and Howard Hughes Medical Institute and Gordon and Betty Moore Foundation Investigator. "The Center will generate critical genomics data that will be shared with scientists throughout California and the rest of the world."

Ecker, holder of the Salk International Council Chair in Genetics, is co-director of the new center along with Michael Snyder, a professor and chair of genetics at Stanford.

Salk and Stanford will lead the center, and U.C. San Diego, Ludwig Institute for Cancer Research, the Scripps Research Institute, the J. Craig Venter Institute andIllumina Inc., all in San Diego, will collaborate on the project, in addition toU.C. Santa Cruz, which will also run the data coordination and management component.

"This Center of Excellence in Stem Cell Genomics shows why we are considered one of the global leaders in stem cell research," says Alan Trounson, president of the stem cell agency. "Bringing together this team to do this kind of work means we will be better able to understand how stem cells change as they grow and become different kinds of cells. That deeper knowledge, that you can only get through a genomic analysis of the cells, will help us develop better ways of using these cells to come up with new treatments for deadly diseases."

In addition to outside collaborations, the center will pursue some fundamental questions and goals of its own, including collecting and characterizing induced pluripotent stem cell lines from patients with familial cardiomyopathy; applying single-cell genomic techniques to better understand cellular subpopulations within diseased and healthy brain and pancreatic tissues; and developing novel computational tools to analyze networks underlying stem cell genome function.

The award includes $19 million for the center team to carry out collaborative projects with California scientists from outside the center, including investigations of disease mechanisms and the development of stem cell-based therapies. The Data Coordination and Management program will enable the research to be shared with other investigators around California and the world.

In addition to the Center of Excellence, the stem cell agency's governing Board, the Independent Citizens Oversight Committee (ICOC), also approved more than $27 million in funding for the Basic Biology V awards. These go to researchers trying to advance the field by tackling significant, unresolved issues in human stem cell biology. Salk Professor Ronald Evans, holder of Salk's March of Dimes Chair in Molecular and Developmental Biology and a Howard Hughes Medical Institute Investigator, was among the recipients. He was awarded $1,491,900 to investigate the role nuclear hormone receptors play in the generation of stem cells, research that holds potential to expand scientists' understanding of cancer cell growth and the regeneration of tissues.

CIRM was established in November 2004 with the passage of Proposition 71, the California Stem Cell Research and Cures Act. The statewide ballot measure, which provided $3 billion in funding for stem cell research at California universities and research institutions, was overwhelmingly approved by voters, and called for the establishment of an entity to make grants and provide loans for stem cell research, research facilities, and other vital research.


Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,500+ scientific posters on ePosters
  • More than 3,700+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

New Stem Cell May Overcome Hurdles for Regenerative Medicine
Scientists have discovered a novel type of pluripotent stem cell capable of developing into any type of tissue whose identity is tied to their location in a developing embryo.
Monday, May 11, 2015
Vital Step in Stem Cell Growth Revealed
Salk scientists' finding could aid regenerative and cancer therapies.
Thursday, May 07, 2015
Salk Scientists Discover a Key to Mending Broken Hearts
Researchers regenerate and heal mouse hearts by using the molecular machinery the animals had all along.
Wednesday, November 12, 2014
Turning Human Skin Cells Into Immune-Fighting White Blood Cells
The fast and safe technique developed at the Salk Institute circumvents problems that have hindered regenerative medicine.
Friday, September 12, 2014
No Extra Mutations in Modified Stem Cells, Study Finds
New results ease previous concerns that gene-editing techniques-used to develop therapies for genetic diseases-could add unwanted mutations to stem cells.
Saturday, July 12, 2014
Salk Institute Receives $3M Gift for Ageing Research
The gift from the Glenn Foundation for Medical Research will allow the Institute to continue conducting research to understand the biology of normal human aging and age-related diseases.
Friday, May 23, 2014
New Stem Cell Research Points to Early Indicators of Schizophrenia
Salk scientists show fundamental differences in early neurons from patients with schizophrenia, supporting the theory that risk for the disease may begin in the womb.
Wednesday, May 14, 2014
Salk Scientists Discover more Versatile Approach to Creating Stem Cells
New method should hasten promise of regenerative medicine.
Wednesday, July 24, 2013
Researchers Chart Epigenomics of Stem Cells That Mimic Early Human Development
Collaborative study will help overcome hurdles to using stem cells to treat diseases and injuries.
Friday, May 10, 2013
Salk Institute Awarded Historic $42 Million Grant to Establish Center for Genomic Medicine
World-renowned research facility receives largest single donation in its 53-year history.
Thursday, January 24, 2013
Salk Scientists Develop Faster, Safer Method for Producing Stem Cells
The new method boosts cell yields and increases safety, helping to get another step closer to regenerative medicine.
Friday, December 07, 2012
Salk Scientists Pinpoint Key Player in Parkinson's Disease Neuron Loss
Stem cell study may help to unravel how a genetic mutation leads to Parkinson's symptoms.
Tuesday, October 23, 2012
Reprogramming Signature may help Overcome Barriers to Regenerative Medicine
Salk scientists show nine genes at heart of epigenetic changes in induced pluripotent stem cells.
Friday, September 21, 2012
Scientists Identify Gene Crucial to Normal Development of Lungs and Brain
Scientists at the Salk Institute for Biological Studies have identified a gene that tells cells to develop multiple cilia, tiny hair-like structures that move fluids through the lungs and brain. Discovery may lead to new ways to replace damaged lung tissues.
Friday, January 13, 2012
Editing Scrambled Genes in Human Stem Cells may Help Realize the Promise of Combined Stem Cell-gene Therapy
Researchers at the Salk Institute successfully edited a diseased gene in patient-specific induced pluripotent stem cells as well as adult stem cells.
Tuesday, May 24, 2011
Scientific News
The Mending Tissue - Cellular Instructions for Tissue Repair
NUS-led collaborative study identifies universal mechanism that explains how tissue shape regulates physiological processes such as wound healing and embryo development.
Tissue Bank Pays Dividends for Brain Cancer Research
Checking what’s in the bank – the Brisbane Breast Bank, that is – has paid dividends for UQ cancer researchers.
iPS Cells Discover Drug Target for Muscle Disease
Researchers have designed a model that reprograms fibroblasts to the early stages of their differentiation into intact muscle cells in a step towards a therapeutic for Duchenne muscular dystrophy.
Engineered Hot Fat Implants Reduce Weight Gain
Scientists at UC Berkeley have developed a novel way to engineer the growth and expansion of energy-burning “good” fat, and then found that this fat helped reduce weight gain and lower blood glucose levels in mice.
Transplanted Stem Cells Can Benefit Retinal Disease Sufferers
Tests on animal models show that MSCs secrete growth factors that suppress causes of diabetic retinopathy and macular degeneration.
MRI Scanners Can Steer Therapeutics to Specific Target Sites
Scientists from the University of Sheffield have discovered MRI scanners, normally used to produce images, can steer cell-based, tumour busting therapies to specific target sites in the body.
Team Finds Early Inflammatory Response Paralyzes T Cells
Findings could have enormous implications for immunotherapy, autoimmune disorders, transplants and other aspects of immunity.
Early Detection of Lung Cancer
The University of Manchester has signed a collaboration agreement with Abcodia to perform proteomics studies on a cohort of non-small cell lung cancer cases from the UKCTOCS biobank, with the aim of discovering new blood-based biomarkers for earlier detection of the disease.
Researchers Identify Drug Candidate for Skin, Hair Regeneration
Formerly undiscovered role of protein may lead to the development of new medications that stimulate hair and skin regeneration in trauma or burn victims.
Basis for New Treatment Options for a Fatal Leukemia in Children Revealed
Detailed molecular analyses allow new insights into the function of tumour cells and options for new treatments.
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FREE!