STEMCELL Technologies Inc. has just released New MesenCult™ Proliferation Kit with MesenPure™ (Mouse), a novel cell culture medium to advance research on mouse mesenchymal stem and progenitor cells (MSCs).
When added to MesenCult™ medium, MesenPure™ supplement enriches mouse bone marrow- or compact bone-derived MSC cultures by reducing the number of hematopoietic cells.
Culturing with MesenPure™ eliminates the time-intensive serial passaging steps and frequent cell culture medium changes normally required to decrease the unwanted hematopoietic cell population typically present in MSC cultures.
Cultures treated with MesenPure™ appear homogeneous and mostly devoid of hematopoietic cells as early as passage zero and also contain increased numbers of mesenchymal stem cells that display more robust differentiation.
This easy-to-use and versatile kit, “may save researchers from having to wait several weeks for homogeneous MSC cultures”, explains Dr. Arthur Sampaio, Senior Scientist at STEMCELL Technologies. “But, I think the greatest advantage to using MesenPure™ may be the ability to use lower-passage cultures. It has been shown that over time, extended passaging can bring about detrimental changes to MSCs, such as a loss of phenotype, senescence, and a decrease in the homing ability and differentiation potential of the cells. By using the MesenCult™ Proliferation Kit with MesenPure™, researchers will be able to study lower passage mouse MSCs, increasing their ability to evaluate the true potential of these cells.”