Corporate Banner
Satellite Banner
Stem Cells, Cellular Therapy & Biobanking
Scientific Community
Become a Member | Sign in
Home>News>This Article

California Company Licenses Human Embryonic Stem Cell Technology from WARF

Published: Tuesday, January 15, 2008
Last Updated: Tuesday, January 15, 2008
Bookmark and Share
BioTime signs licensing agreement with WARF for 173 patents and patent applications relating to human embryonic stem cell technology created at the UW-Madison.

BioTime, Inc. has signed a licensing agreement with the Wisconsin Alumni Research Foundation (WARF) for 173 patents and patent applications relating to human embryonic stem cell technology created by James Thomson at the University of Wisconsin-Madison.

BioTime develops blood plasma volume expanders and has recently entered the field of regenerative medicine through its wholly owned subsidiary, Embryome Sciences, Inc., through which it plans to develop new medical and research products using embryonic stem cell technology.

Embryome Sciences plans to develop and commercialize a technology platform called Embryomics™, a collection of research tools that can facilitate stem cell research by providing researchers with new products for the identification, scale-up, and purification of the many cell types that emerge from human embryonic stem cells.

"I'm pleased to be able to work with WARF to commercialize our Embryomics technology in the research market. The license of the WARF patents will allow us to manufacture and commercialize human embryonic stem cell-derived cell types and related products for scientists to use in research and in drug discovery," says BioTime Chief Executive Michael West.

WARF, the private, non-profit patenting and licensing organization that supports UW-Madison, has had a long relationship with BioTime's West.

"We value Dr. West's efforts through the years to advance the emerging field of regenerative medicine, as well as his support of Dr. Thomson's research and of WARF," says WARF Managing Director Carl E. Gulbrandsen.

West, the founder of Geron Corporation, provided early support for the work of James Thomson, the UW-Madison researcher who first successfully isolated human embryonic stem cells in 1998. Geron became WARF's first commercial licensee of the technology.

After Geron, West continued to advance stem cell science while leading Advanced Cell Technology and later moved to do the same as head of BioTime.

WARF officials note that this licensing agreement with BioTime demonstrates that commercial interest in human embryonic stem cells remains strong. With this agreement, WARF now has completed 23 licensing agreements for stem cell technologies with 17 companies.

BioTime plans to launch three kinds of Embryonics research products in the next two years. The first product is a commercial database that will serve as a map for researchers to navigate the complexities of human development and to identify the many hundreds of cell types that can be derived from human embryonic stem cells. When operational, the relational database will permit researchers to chart the cell lineages of human development, the genes expressed in those cell types, and antigens present on the cell surface of those cells that can be used in purification.

BioTime has recently licensed relational database technology to develop this Web-based database, and is targeting an initial launch with a database map of the murine embryome by January 2008, and the human embryome by June 2008.

To manufacture specific cell types from embryonic stem cells, researchers need to use factors that signal to stem cells to become a desired cell type.  BioTime plans to develop growth and differentiation factors for this purpose, and hopes to launch the first of these EScalate™ products beginning in March 2008.

BioTime also plans to launch new products useful in the identification and purification of the hundreds of cells that originate from human embryonic stem cells. These molecules, known as "ligands to differentiation antigens," are expected to be useful to both basic research and in the manufacture of safe cell-based therapies.

Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,600+ scientific posters on ePosters
  • More than 3,800+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

New Induced Stem Cells May Unmask Cancer at Earliest Stage
A team of Wisconsin scientists observes the onset of the blood cancer leukemia by coaxing healthy and diseased human bone marrow to become embryonic-like stem cells.
Tuesday, February 08, 2011
Gene Regulating Human Brain Development Identified
New findings by Wisconsin-Madison scientists reveal the main genetic factor responsible for instructing cells at the earliest stages of embryonic development.
Friday, July 02, 2010
Liver Cells Grown From Patients’ Skin Cells Could Lead to Treatment of Liver Diseases
Wisconsin scientists have successfully produced liver cells from patients’ skin cells opening the possibility of treating liver diseases.
Monday, October 12, 2009
Stem Cells Show Power to Predict Disease, Drug Toxicity
Scientists have used human embryonic stem cells to predict the toxic effects of drugs and provide chemical clues to diagnosing disease.
Monday, December 10, 2007
UW-Madison Scientists Guide Human Skin Cells to Embryonic State
Researchers reports the genetic reprogramming of human skin cells to create cells indistinguishable from embryonic stem cells in a paper to be published online.
Thursday, November 22, 2007
Stem Cell Therapy Rescues Motor Neurons in ALS Model
University of Wisconsin-Madison scientists show that it is possible to rescue the dying neurons characteristics of ALS by using cell-based therapies.
Wednesday, August 01, 2007
UW Launches Study Testing Adult Stem Cells for Repair of Heart Damage
The University of Wisconsin will take part in a clinical trial that involves investigation of patient’s own stem cells to treat severe coronary artery disease.
Tuesday, March 20, 2007
Scientific News
Snapshot Turns T Cell Immunology on its Head
New research may have implications for 1 diabetes sufferers.
Developing a Gel that Mimics Human Breast for Cancer Research
Scientists at the Universities of Manchester and Nottingham have been funded to develop a gel that will match many of the biological structures of human breast tissue, to advance cancer research and reduce animal testing.
Lung Repair and Regeneration Gene Discovered
New role for hedgehog gene offers better understanding of lung disease.
Restoring Vision with Stem Cells
Age-related macular degeneration (AMRD) could be treated by transplanting photoreceptors produced by the directed differentiation of stem cells, thanks to findings published today by Professor Gilbert Bernier of the University of Montreal and its affiliated Maisonneuve-Rosemont Hospital.
The Age of Humans Controlling Microbes
Engineered bacteria could soon be used to detect environmental toxins, treat diseases, and sustainably produce chemicals and fuels.
Gene Expression: A Snapshot of Stem Cell Development
New genes found that regulate development of stem cells.
Tissue-Engineered Colon from Human Cells
A study by scientists at Children’s Hospital Los Angeles has shown that tissue-engineered colon derived from human cells is able to develop the many specialized nerves required for function, mimicking the neuronal population found in native colon.
Tension Helps Heart Cells Develop Normally in the Lab
Stanford engineers have uncovered the important role tension plays in growing heart cells out of the body.
Urine Excretion From Stem Cell-Derived Kidneys
Researchers report a strategy for enabling urine excretion from kidneys grown from stem cells.
Stem Cell Research Hints at Evolution of Human Brain
Researchers at UC San Francisco have succeeded in mapping the genetic signature of a unique group of stem cells in the human brain that seem to generate most of the neurons in our massive cerebral cortex.
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,600+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,800+ scientific videos