Corporate Banner
Satellite Banner
Stem Cells, Cellular Therapy & Biobanking
>
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

454 Sequencing at the Forefront of Bone Marrow and Stem Cell Therapy Research

Published: Monday, June 30, 2008
Last Updated: Monday, June 30, 2008
Bookmark and Share
Roche Genome Sequencer FLX System will create new opportunities for HLA research at the Blood Centre Linz, Austria.

The Blood Centre Linz, Austria has purchased a Genome Sequencer FLX System from Roche, for use in research on rejection reactions in Bone Marrow and Stem Cell transplantation. Using conventional Sanger sequencing it can take weeks to analyze large DNA regions.

The Genome Sequencer FLX System can achieve this task within hours, improving efficiency and reducing costs. The ultimate goal of the research undertaken with the Genome Sequencer System is to create a significant reduction in the high rate of rejection reactions in transplantation.

Typically, the odds of finding a suitable stem cell donor is 1 in 500,000. Every year in the German speaking countries, approximately 12,000 people require urgent transplantations. The success of these transplantations is largely dependent on an exact tissue matching based upon HLA typing.

With the Genome Sequencer from Roche Diagnostics, the researchers at the Blood Centre Linz will concentrate on making the HLA typing application significantly quicker and more efficient in order to ensure a significant decrease in graft rejection by a better matching recipients to donors.


Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,500+ scientific posters on ePosters
  • More than 3,800+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

First European Laboratory Obtains Accreditation for New Tissue-Typing Method for Stem Cell Transplants
Tests based on next-generation sequencing with Roche’s GS Junior System.
Thursday, February 28, 2013
Birmingham hospital uses Roche automation solution at blood sciences laboratory
Roche’s automated track system is being used at Queen Elizabeth Hospital to streamline processes and improve turnaround times.
Saturday, June 02, 2012
Roche’s xCELLigence Cardio Instrument Used to Study Stem Cell-Derived Cardiomyocytes
Instrument detected beating rhythm and proarrhythmic effects of nine different compounds on a monolayer of cells, providing evidence for the potential of future screening assays.
Monday, February 13, 2012
Roche’s new RTCA Cardio Instrument for Label-Free Functional Cardiomyocyte Toxicity Testing
New medium-throughput cell analyzer utilizes impedance readings to monitor cardiac beating and cellular events in real time.
Wednesday, September 29, 2010
Roche Applied Science Introduces new xCELLigence RTCA MP Instrument
The xCELLigence RTCA MP allows high throughput online-measurement of cell activities without labeling.
Friday, December 05, 2008
Scientific News
The Mending Tissue - Cellular Instructions for Tissue Repair
NUS-led collaborative study identifies universal mechanism that explains how tissue shape regulates physiological processes such as wound healing and embryo development.
Tissue Bank Pays Dividends for Brain Cancer Research
Checking what’s in the bank – the Brisbane Breast Bank, that is – has paid dividends for UQ cancer researchers.
iPS Cells Discover Drug Target for Muscle Disease
Researchers have designed a model that reprograms fibroblasts to the early stages of their differentiation into intact muscle cells in a step towards a therapeutic for Duchenne muscular dystrophy.
Engineered Hot Fat Implants Reduce Weight Gain
Scientists at UC Berkeley have developed a novel way to engineer the growth and expansion of energy-burning “good” fat, and then found that this fat helped reduce weight gain and lower blood glucose levels in mice.
Transplanted Stem Cells Can Benefit Retinal Disease Sufferers
Tests on animal models show that MSCs secrete growth factors that suppress causes of diabetic retinopathy and macular degeneration.
MRI Scanners Can Steer Therapeutics to Specific Target Sites
Scientists from the University of Sheffield have discovered MRI scanners, normally used to produce images, can steer cell-based, tumour busting therapies to specific target sites in the body.
Team Finds Early Inflammatory Response Paralyzes T Cells
Findings could have enormous implications for immunotherapy, autoimmune disorders, transplants and other aspects of immunity.
Early Detection of Lung Cancer
The University of Manchester has signed a collaboration agreement with Abcodia to perform proteomics studies on a cohort of non-small cell lung cancer cases from the UKCTOCS biobank, with the aim of discovering new blood-based biomarkers for earlier detection of the disease.
Researchers Identify Drug Candidate for Skin, Hair Regeneration
Formerly undiscovered role of protein may lead to the development of new medications that stimulate hair and skin regeneration in trauma or burn victims.
Basis for New Treatment Options for a Fatal Leukemia in Children Revealed
Detailed molecular analyses allow new insights into the function of tumour cells and options for new treatments.
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,800+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FREE!