Following the launch of the xCELLigence RTCA SP Instrument in June, Roche Applied Science has introduced the new xCELLigence RTCA MP Instrument.
In comparison with the RTCA SP, the new RTCA MP Instrument has a higher throughput capacity and is versatile which enables application on a wider range of experimental set-ups.
The system features six E-Plates 96 as opposed to only one in the RTCA SP. Each E-Plate can be individually addressed in independent experiments.
The heart of each xCELLigence System is a micro-electronic biosensor which is built into each well of the standard 96 well E Plate microtiter plates. A cell which has contact with the sensor changes the electrical impedance between the microelectrodes. Each change in the cell’s status leads to changes in the impedance measurements and can therefore be easily detected in real time. Labelling of the cells, which can induce non-physiological changes in the cells, is not necessary. The system is label free and requires no reporters.