Features and Benefits • Generates functional organelles for metabolism and disease research • Includes protease inhibitor to manage degradation • Measures integrity with included Neutral Red dye • Choose from multiple options to obtain enriched fractions • Enriched fractions for intact and functional lysosomes from tissues and cells • Suitable for functional studies including protein degradation
General description Lysosomes are organelles ubiquitous in most pro- and eukaryotic cell. They contain many acid hydrolases that take part in protein degradation in the cell. Lysosomes also contain lipases, nucleases and polysaccharidases and deficiencies in some of these enzymes lead to specific lysosomal storage diseases such as Tay Sachs, Gaucher, Hunter disease and others. They also contribute to maintaining cellular homeostasis. Malfunctions in this organelle directly impact cell behavior and fate. Lysosomes may also be involved in other cellular processes such as Albinism and aging.