Corporate Banner
Satellite Banner
ADME Tox
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Joining the Digital Age

Published: Thursday, February 21, 2013
Last Updated: Thursday, February 21, 2013
Bookmark and Share
TES Pharma has recently purchased an HP D300 Digital Dispenser, and is now reaping the benefits of direct titration with improved assay reproducibility and more time to perform exploratory research.

TES Pharma is a small biotechnology company based in Corciano near Perugia, Italy, specializing in compound screening for pharmaceutical drug discovery. Combining an in depth knowledge of drug design and chemistry with systems and molecular biology approaches, the Company works collaboratively with partners around the world to combine the best aspects of academia and commercial pharmaceutical development.

TES Pharma’s small yet highly skilled and experienced team works closely with the University of Perugia to rapidly develop and explore novel compounds which may be of interest in various disease states. To standardize the Company’s workflow, as well as to free up more staff time for research activities, TES Pharma has recently invested in an HP D300 Digital Dispenser from Tecan. Graeme Robertson, a co-founder of TES Pharma, explained: “The drug discovery process is becoming increasingly highly specialized, often involving multiple partners with distinct skill sets working together to deliver novel therapeutic agents. Our core competence at TES Pharma lies in the development of advanced screening assays, and we believe that, by working closely with academic partners with expertise in individual conditions or disease areas, we can eliminate some of the drawbacks inherent in traditional drug discovery pipelines.”

“To do this we need to concentrate on our own expertise in core areas, and our HP D300 Digital Dispenser allows us to use our time more effectively, without compromising on results. As a small collaborative research facility we do not have a high enough throughput to effectively use complete laboratory automation systems, but the HP D300 is easy to use and its precision dispensing eliminates the need for tedious manual dilutions. Digital titration also offers several key advantages over traditional manual protocols in terms of reducing waste of valuable compounds, limiting the DMSO content for sensitive assays and increasing reproducibility, but it is the staff time it creates that is most important, liberating skilled individuals to perform more exploratory research. It also allows us to limit the number of variables in a way that would not be possible manually, helping us to rapidly characterize novel biological activities which might otherwise be missed.”


Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,400+ scientific posters on ePosters
  • More than 3,700+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Tecan and Pion Expand Collaboration to Develop Automated Drug Screening Solutions
The new automated application provides scalability from an entry-level manual system to a fully automated system with medium or high throughput.
Thursday, July 16, 2009
A perfect fit for the Freedom EVO® 75 in forensic toxicology
Immunalysis Corporation tailors the Tecan Freedom EVO 75 liquid handing workstation as the platform of choice to provide customized semi and fully automated drugs of abuse screening solutions.
Friday, March 14, 2008
Scientific News
Self-Assembling, Biomimetic Membranes May Aid Water Filtration
A synthetic membrane that self assembles and is easily produced may lead to better gas separation, water purification, drug delivery and DNA recognition, according to an international team of researchers.
Study Questions Presence in Blood of Heart-Healthy Molecules from Fish Oil Supplements
A new study from the Perelman School of Medicine at the University of Pennsylvania questions the relevance of fish oil-derived SPMs and their purported anti-inflammatory effects in humans.
New Material Opens Possibilities for Super-Long-Acting Pills
A pH-responsive polymer gel could create swallow able devices, including capsules for ultra-long drug delivery.
Long-sought Discovery Fills in Missing Details of Cell 'Switchboard'
A biomedical breakthrough reveals never-before-seen details of the human body’s cellular switchboard that regulates sensory and hormonal responses.
Tracking Breast Cancer Before it Grows
A team of scientists led by University of Saskatchewan researcher Saroj Kumar is using cutting-edge Canadian Light Source techniques to screen and treat breast cancer at its earliest changes.
Zebrafish Reveal Drugs that may Improve Bone Marrow Transplant
Compounds boost stem cell engraftment; could allow more matches for patients with cancer and blood diseases.
Teeth Reveal Lifetime Exposures to Metals, Toxins
Researchers have identified dental biomarkers to reveal links between early iron exposure and late life brain diseases.
An Innovative Algorithm to Decipher How Drugs Work Inside the Body
Researchers at Columbia University Medical Center (CUMC) have developed a computer algorithm that is helping scientists see how drugs produce pharmacological effects inside the body.
Uncovering the Spread of Bacteria in Pneumonia
Northwestern Medicine scientists have discovered the role a toxin produced by a pneumonia-causing bacterium plays in the spread of infection from the lungs to the bloodstream in hospitalized patients.
Ferring Bets on Bacteriophages to Treat Inflammatory Bowel Disease
Ferring Pharmaceuticals have annoucned that it will collaborate with Intralytix in the latest phase of its early stage development programme for a bacteriophage-based therapy for inflammatory bowel disease (IBD).
SELECTBIO

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,400+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FREE!