Corporate Banner
Satellite Banner
Scientific Community
Become a Member | Sign in
Home>News>This Article

The University of Paris Selects ACD/Percepta Software to Enhance Teaching and Research into Pharmaceuticals

Published: Monday, December 16, 2013
Last Updated: Monday, December 16, 2013
Bookmark and Share
ADME/Tox and PhysChem predictions on the Percepta Platform will help educate and train the next generation of pharmaceutical scientists.

The Université Paris-Sud, School of Pharmacy, has selected ACD/Labs’ ADME, Toxicity, and PhysChem predictors on the ACD/Percepta Platform, to enable in silico evaluation of pharmaceutical substances and research compounds.

The software is to be applied by undergraduate students to help them understand the effect of drugs on the body in terms of toxicity, and the body’s ability to use and dispose of a drug, i.e., ADME properties (absorption, distribution, metabolism, and excretion). Graduate students will use the software in their investigations towards innovative therapeutics from natural products. 

“As an educator I want to prepare my students for a successful career in the pharmaceutical industry. Software is used more and more, and our students will benefit from being exposed to these tools early in their education”, says Prof. Delphine Joseph. “Ease of use was very important to us, particularly since undergraduate classes will only use the software for one academic session, to understand the concepts behind drug design. Our research programs will benefit because graduate students will be able to profile synthetic modifications to molecular structures in silico, and investigate the effect on physiological behavior.”

Percepta modules provide predictions for oral bioavailability, CYP450 inhibition, blood brain barrier permeation, hERG inhibition, lipophilicity, and many other physiologically relevant properties. The values and supporting information provided in the software (such as similar structures, effect of pH, and color coded mapping) can help scientists understand the behavior of molecular structures, and direct discovery research in terms of achieving an optimal drug-like profile.

Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,600+ scientific posters on ePosters
  • More than 3,800+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Scientific News
New Gene Therapy for Vision Loss From a Mitochondrial Disease
NIH-funded study shows success in targeting mitochondrial DNA in mice.
Self-Propelled Powder to Stop Bleeding
UBC researchers have created the first self-propelled particles capable of delivering coagulants against the flow of blood to treat severe bleeding, a potentially huge advancement in trauma care.
Tension Helps Heart Cells Develop Normally in the Lab
Stanford engineers have uncovered the important role tension plays in growing heart cells out of the body.
Controlling Body Temperature in Response to 'Fight or Flight'
New research in The FASEB Journal suggests that blocking TRPV1 protein causes an increased release of noradrenaline, leading to an increase in core body temperatures.
Inroads Against Leukaemia
Potential for halting disease in molecule isolated from sea sponges.
Researchers Disguise Drugs As Platelets to Target Cancer
Researchers have for the first time developed a technique that coats anticancer drugs in membranes made from a patient’s own platelets.
A Fundamental Protection Mechanism Against Formalin In Mammals is Revealed
Formaldehyde, or formalin, is well known to all of us as a common chemical used in many industrial processes and also as a preservative, remarkably we also produce formaldehyde in our bodies.
Drug Used To Treat HIV Linked to Lower Bone Mass in Newborns
NIH study finds mothers’ use of tenofovir tied to lower bone mineral content in babies.
Bone Risks Linked to Genetic Variants
A large-scale genomic study uncovered novel genetic variants and led researchers to an unexpected gene that affects bone density and fracture risk.
Combo of 3 Antibiotics Can Kill Deadly Staph Infections
Three antibiotics that, individually, are not effective against a drug-resistant staph infection can kill the deadly pathogen when combined as a trio, according to new research.

Skyscraper Banner
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,600+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,800+ scientific videos