Corporate Banner
Satellite Banner
ADME Tox
Scientific Community
 
Become a Member | Sign in
Home>Products>This Product
  Products


MaxDiscovery™ Caspase-3 Fluorescence Detection Kit

Product Description
Caspase-3 is a ubiquitously-expressed cysteine protease involved in programmed cell death (apoptosis). In nonapoptotic cells, this enzyme exists as an inactive zymogen known as procaspase-3. Intracellular procaspase-3 is activated when cells are committed to die via apoptosis; induction of the cell death machinery eventually triggers activation of the zymogen by proteolytic cleavage of the zymogen to an active heterodimer comprised of 17 kDa and 12 kDa subunits. The active enzyme cleaves a number of intracellular protein targets important for cell survival. Therefore, monitoring caspase-3 enzyme activity is a fundamental means to measure apoptosis in cells. This assay is an important tool for apoptosis research as well as investigating the apoptotic effects of experimental drug formulations and cell transfection. The MaxDiscovery™ Caspase-3 Fluorescence Detection Kit is a fluorescence microplate-based assay to directly measure caspase-3 activation in cultured cells. This kit enables biomedical researchers to determine caspase-3 levels in cultured cells from a broad range of cell lines. The assay utilizes a simple, proven enzymatic assay to detect activated enzyme. Because caspase-3 is expressed in every cell type, the assay can be performed using any mammalian cell line.
Product MaxDiscovery™ Caspase-3 Fluorescence Detection Kit
Company BIOO Scientific - Product Directory
Price Request a quote
More Information View company product page
Catalog Number 5810
Quantity 1 x 96 wells
Company Logo

BIOO Scientific - Product Directory
3913 Todd Lane Suite 312 Austin, TX 78744, USA

Tel: +1 512-707-8993
Fax: +1 512-707-8122
Email: info@biooscientific.com



Scientific News
Fighting Cancer with Sticky Nanoparticles
Treatment that uses bioadhesive nanoparticles drug carriers proved more effective than conventional treatments for certain cancers.
Stem Cell ‘Heart Patch’ Almost Perfected
Scientists aiming to perfect and test 3D "heart patches" in animal model, last hurdle before human patients.
Smart Material Hunts Cancers
Team has created smart material that locates and images cancer or tumour sites in tissue.
Targeting Fat to Treat Cancer
Researchers develop novel cancer treatment that halts fat synthesis in cells, stunting tumors.
Reprogramming Lymph Nodes to Fight MS
Bioengineers work to reprogram lymph node function to fight multiple sclerosis.
Arms Race with a Superbug
Scientists have discovered that increased risk of superbug infection can be directly casued by immune system response to invading bacteria.
Genes Essential to Life Discovered
Genes critical for life are discovered in humans and mice as part of large-scale phenotyping study.
High-Capacity Nanoparticles
New type of nanoparticle can now have three or more drugs packaged within it, allowing for customised cancer therapy.
Manipulation of Liquid Crystals Could Help Control Drug-Delivery Process
Computer modeling, real-world testing yields new method.
Puttng Cells Through Their Paces
An obstacle course for human lung cells could be the answer for better testing the effectiveness of potential new drugs.

SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,000+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!