Covance, with headquarters in Princeton, New Jersey, is one of the world’s largest and most comprehensive drug development services companies, with annual revenues greater than $2 billion, employees in more than 60 countries, and more than 11,000 employees worldwide.
Nonclinical Development: Toxicology, Research Products, Analytical Services
• Managed 443 compound development programs (>250 IND/CTA enabling), with over 100 different sponsors, which led to 41 IND/CTA applications in 2009 • Performed best-in-class productivity cycle times: FIA to FIH in 22 weeks • Dedicated Capacity Agreements with several major pharma customers • Greater than 2.5M sq ft of research space
Clinical Development: Clinical Pharmacology, Clinical, Central Labs
• Supported 50% of latest breakthrough cancer treatments • Supported development of the top 25 currently marketed medicines • 70% of clinical programs on or ahead of enrollment timelines • Broad-based, scalable and market-leading, Biomarker capability • 99% of samples received within stability • 145 million laboratory tests; 83,000 investigator sites; 100 countries • Seven Clinical Pharmacology units with ~500 beds
Periapproval & Market Access
• Results-driven reimbursement support for >60% of the biologics market • Designed and managed world’s largest safety registry ever – iPledge • Team of experts dedicated to risk management and Pharmacovigilance • Bi-coastal call center capabilities to deliver patient and physician support
Envigo Rat Models Proven to be Susceptible to Intra-Vaginal HSV-2 Infection and Protectable Scientific findings establish the effectiveness of new approach to investigate the protective effects of vaccine candidates and anti-viral microbodies and to study asymptomatic primary genital HSV-2 infection.Food Triggers Creation of Regulatory T Cells IBS researchers document how normal diet establishes immune tolerance conditions in the small intestine.Counting Cancer-busting Oxygen Molecules Researchers from the Centre for Nanoscale BioPhotonics (CNBP), an Australian Research Centre of Excellence, have shown that nanoparticles used in combination with X-rays, are a viable method for killing cancer cells deep within the living body.Crowdfunding the Fight Against Cancer From budding social causes to groundbreaking businesses to the next big band, crowdfunding has helped connect countless worthy projects with like-minded people willing to support their efforts, even in small ways. But could crowdfunding help fight cancer?
Keeping Tumor Growth at Bay Engineers at Washington University in St. Louis found a way to keep a cancerous tumor from growing by using nanoparticles of the main ingredient in common antacid tablets.Cancer Cells Kill Off Healthy Neighbours Cancer cells create space to grow by killing off surrounding healthy cells, according to UK researchers working with fruit flies.Future of Medicine Could be Found in a Tiny Crystal Ball A Drexel University materials scientist has discovered a way to grow a crystal ball in a lab. Not the kind that soothsayers use to predict the future, but a microscopic version that could be used to encapsulate medication in a way that would allow it to deliver its curative payload more effectively inside the body.Bile Acid Supports Production of Blood Stem Cells A research group at Lund University has been able to show that bile acid is transferred from the mother to the foetus via the placenta to enable the foetus to produce blood stem cells.Chemical Used to Replace BPA is Potentially Toxic This study is the first to examine the effects of BPA and BPS on brain cells and genes that control the growth and function of organs involved in reproduction.A Better Model for Parkinson's Scientists at EPFL solve a longstanding problem with modeling Parkinson’s disease in animals. Using newfound insights, they improve both cell and animal models for the disease, which can propel research and drug development.