Corporate Banner
Satellite Banner
Scientific Community
Become a Member | Sign in
Home>Products>This Product

Sirius inForm

Product Image
Product Description

The more that formulators can learn in the chemistry lab, the better they can design formulations that will deliver the desired performance. Whether it’s controlled release, solubility enhancement or precipitation inhibition that’s required, the novel assays in Sirius inForm will show how drugs behave under a wide range of conditions. It’s a powerful tool to investigate ionisation, solubility, supersaturation, dissolution and lipolysis.
Automation and precision ensure high quality data, with temperature and pH under constant control and biorelevant conditions established using SIFs, SLFs or SGFs. Please see our Application Note range for more information.
Dissolution: Biorelevant, biphasic, automated
Sirius inForm bridges the gap between research-based micro-scale dissolution and the compendial world. Innovative methods such as biphasic dissolution and gradient pH adjustments show how a drug would behave under biorelevant conditions. Automation and precision engineering ensure that dissolution experiments are accurate and highly reproducible.
Solubility, controlled supersaturation, precipitation
With many new drugs now requiring solubility enhancement, formulators need ways to characterize supersaturation and precipitation. Sirius inForm measures solubility using the CheqSol method; new assays report the extent and duration of supersaturation, precipitation rates and excipient gain factors. Uniquely, concentrations are calculated from measured pH, which eliminates interference by suspended solids. There is also a UV option for controlled supersaturation studies.
A versatile platform
Sirius inForm is a versatile platform for automated analysis of solutions. It provides temperature control and high quality stirring, pH measurement and control, ability to add sample  and reagents automatically, in-situ UV measurement and the ability to remove aliquots of sample for off-line analysis. Lipolysis assays to study digestion of lipid-based formulations are supported. UV enhancements include multi-component sensing, and Tyndall Rayleigh scattering correction to reduce the effect of suspended solids during dissolution studies.

Product Sirius inForm
Company Sirius Analytical Instruments Ltd
Price Request a quote
More Information View company product page
Catalog Number Unspecified
Quantity Unspecified
Company Logo

Sirius Analytical Instruments Ltd
Forest Row Business Park, Station Road, Forest Row, East Sussex. RH18 5DW

Tel: +44 (0) 1342 820720
Fax: +44 (0) 1342 820725

Scientific News
Salford Lung Study - The First Real World Clinical Trial
In this podcast, we learn about the Salford Lung Study and its potential to revolutionize the way we assess new drugs and treatments around the world.
Study Finds Key Regulator in Pulmonary Fibrosis
Researchers identify an enzyme that could open the way to therpies for chronic fatal lung disease.
Signaling Pathway Could Be Key to Improved Osteoporosis Treatment
Inhibition of SIK2 enzyme both stimulates bone formation and reduces bone breakdown in animal model.
Ovarian Cancer Insight
Study showed tumours release cytokines to attract macrophages, which secrete growth factors that in turn promote tumour growth.
Substance Can Potentially Postpone Aging
Researchers bridge the gap between two main aging theories - repairs to the DNA and poor functioning mitochondria.
Untangling Cause Of Memory Loss In Neurodegenerative Diseases
NIH-funded mouse study identifies a possible therapeutic target for a family of disorders.
New Model for Understanding Human Myeloma
Researchers develop mouse model where mice carry six human genes involved in human tumour growth.
Preventing Alzheimer's in Mice
Researchers have prevented the Alzheimer’s development in mice by using a virus delivery system to transport a specific gene into the brain.
New Platform for Roundworms Could Speed Up Drug Delivery
Researchers have developed a large-scale in vitro drug discovery platform that could speed up scientific research.
Scientists Speed Up Muscle Repair
Researchers discovered genetically modified mice were able to support far more regenerative stem cells, for muscle repair, than previously thought.


SELECTBIO Market Reports
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,100+ scientific videos