Corporate Banner
Satellite Banner
ADME Tox
Scientific Community
 
Become a Member | Sign in
Home>Products>This Product
  Products


Sirius inForm

Product Image
Product Description

The more that formulators can learn in the chemistry lab, the better they can design formulations that will deliver the desired performance. Whether it’s controlled release, solubility enhancement or precipitation inhibition that’s required, the novel assays in Sirius inForm will show how drugs behave under a wide range of conditions. It’s a powerful tool to investigate ionisation, solubility, supersaturation, dissolution and lipolysis.
Automation and precision ensure high quality data, with temperature and pH under constant control and biorelevant conditions established using SIFs, SLFs or SGFs. Please see our Application Note range for more information.
 
Dissolution: Biorelevant, biphasic, automated
Sirius inForm bridges the gap between research-based micro-scale dissolution and the compendial world. Innovative methods such as biphasic dissolution and gradient pH adjustments show how a drug would behave under biorelevant conditions. Automation and precision engineering ensure that dissolution experiments are accurate and highly reproducible.
 
Solubility, controlled supersaturation, precipitation
With many new drugs now requiring solubility enhancement, formulators need ways to characterize supersaturation and precipitation. Sirius inForm measures solubility using the CheqSol method; new assays report the extent and duration of supersaturation, precipitation rates and excipient gain factors. Uniquely, concentrations are calculated from measured pH, which eliminates interference by suspended solids. There is also a UV option for controlled supersaturation studies.
 
A versatile platform
Sirius inForm is a versatile platform for automated analysis of solutions. It provides temperature control and high quality stirring, pH measurement and control, ability to add sample  and reagents automatically, in-situ UV measurement and the ability to remove aliquots of sample for off-line analysis. Lipolysis assays to study digestion of lipid-based formulations are supported. UV enhancements include multi-component sensing, and Tyndall Rayleigh scattering correction to reduce the effect of suspended solids during dissolution studies.

Product Sirius inForm
Company Sirius Analytical Instruments Ltd
Price Request a quote
More Information View company product page
Catalog Number Unspecified
Quantity Unspecified
Company Logo

Sirius Analytical Instruments Ltd
Forest Row Business Park, Station Road, Forest Row, East Sussex. RH18 5DW

Tel: +44 (0) 1342 820720
Fax: +44 (0) 1342 820725
Email: sales@sirius-analytical.com



Scientific News
Fighting Cancer with Sticky Nanoparticles
Treatment that uses bioadhesive nanoparticles drug carriers proved more effective than conventional treatments for certain cancers.
Stem Cell ‘Heart Patch’ Almost Perfected
Scientists aiming to perfect and test 3D "heart patches" in animal model, last hurdle before human patients.
Smart Material Hunts Cancers
Team has created smart material that locates and images cancer or tumour sites in tissue.
Targeting Fat to Treat Cancer
Researchers develop novel cancer treatment that halts fat synthesis in cells, stunting tumors.
Reprogramming Lymph Nodes to Fight MS
Bioengineers work to reprogram lymph node function to fight multiple sclerosis.
Arms Race with a Superbug
Scientists have discovered that increased risk of superbug infection can be directly casued by immune system response to invading bacteria.
Genes Essential to Life Discovered
Genes critical for life are discovered in humans and mice as part of large-scale phenotyping study.
High-Capacity Nanoparticles
New type of nanoparticle can now have three or more drugs packaged within it, allowing for customised cancer therapy.
Manipulation of Liquid Crystals Could Help Control Drug-Delivery Process
Computer modeling, real-world testing yields new method.
Puttng Cells Through Their Paces
An obstacle course for human lung cells could be the answer for better testing the effectiveness of potential new drugs.

SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,000+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!