News

Mount Sinai researchers have revealed the biological mechanisms by which a family of proteins known as histone deacetylases (HDACs) activate immune system cells linked to inflammatory bowel disease (IBD) and other inflammatory diseases.

In a first demonstration of “electron videography,” researchers have captured a microscopic moving picture of the delicate dance between proteins and lipids found in cell membranes.

A heart attack will leave a permanent scar on a human heart, yet other animals, including zebrafish, can clear cardiac scar tissue and regrow damaged muscle. A new study sheds light on the molecular and cellular mechanisms at play in this regeneration.

Researchers have uncovered a novel mechanism underlying memory formation that involves rapid changes to DNA structure.

Observing proteins precisely within cells is extremely important for many branches of research but has been a significant technical challenge. A research group has now overcome this hurdle: With a novel method.

In recent years, a growing body of research has shown that the human body can “remember” the pain of newborn injuries–including life-saving surgeries–all the way into adolescence.

Contrary to previous assumptions, nerve cells in the human neocortex are wired differently than in mice – human neurons communicate in one direction.

Using a novel imaging technique to view cells in 3D, researchers have been able to identify two genes that control how melanoma skin cancer cells change shape – offering potential drug targets to prevent the cancer from spreading.

Human mini-lungs can mimic the response of animals when exposed to certain nanomaterials. Though not expected to replace animal models completely, human organoids could soon lead to significant reductions in research animal numbers.

Researchers have developed a powerful, new technique to generate “movies” of changing protein structures and speeds of up to 50 frames per second.