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Webcasts
Webcasts - Imaging Biomarkers - Future or RealityImaging Biomarkers - Future or Reality
Edwin van Beek, University of Edinburgh, speaking at Diagnostics & Biomarkers 2015.
Webcasts - Genome-Scale Protein Expression Analysis of Individual Solid TumorsGenome-Scale Protein Expression Analysis of Individual Solid Tumors
Metodi Metodiev, University of Essex, speaking at Diagnostics and Biomarkers 2015.

Market Reports
Immunoassay Auto Trends 2014
HTStec

This report comprehensively documents current practices and preferences in immunoassays and to understand future user requirements, particularly with respect to immunoassay automation.
Epigenetic Modification Screening Trends 2014
HTStec

This market report summarizes the results of HTStec’s 3nd industry-wide global web-based benchmarking survey on epigenetic modification screening carried out in May 2014.
Chromatography Accessories and Consumables Market by Types, Technology & End-users - Trends & Global Forecasts to 2018
MarketsandMarkets

The chromatography accessories and consumables market demands significant investments in R&D in order to constantly come up with new and innovative products and technologies.
Molecular Spectroscopy Market by Technology & Application - Forecast to 2018
MarketsandMarkets

Over the years, the molecular spectroscopy market, comprising instruments, consumables, and services, has witnessed various technological advancements. These advancements have led to a growth in the number of molecular spectroscopy applications.
Multi-Channel Pipettor QC Trends 2014
HTStec

Multi-channel pipettors are essential tools in most life science laboratories today. Yet the impact of undertaking quality control (QC) measures on improving data quality, enhancing productivity/efficiency and reducing experimental failures has only relatively recently been recognized. Understanding how lab users approach the issue of pipettor QC is important as the industry struggles to adopt standards for automated pipetting.
Biomarkers Market 2013 - 2020
Allied Market Research

Disease diagnostic application remains the key area of application that is expected to reach 6.1 $billion in 2020. However, application of diagnostic biomarkers in forensics and molecular diagnostics is catching up quite significantly. Molecular diagnostics is expected to grow at a CAGR of 17.6% from 2013 to 2020.
DNA Sequencing
RI Technologies

This report presents an in depth analysis of DNA sequencing market. The study emphasizes on both, the methods and instruments/software of DNA sequencing in medical research, agriculture and animal husbandry and DNA testing and forensics application areas.
Blood - Components, Testing & Collection
RI Technologies

This market insight report gives an insight into global blood ? components, testing and collection market. The report also provides market analytics by Product Type.
Bionanotechnology
RI Technologies

This report on Bionanotechnology studies the impact of nanotechnology in various biotechnology applications. The study focuses on major applications including food, drug discovery and development, diagnostic tools and devices, and other (bionanosensors).
Multi-Mode Microplate Reader Trends 2013
HTStec

This market report summarizes the results of HTStec’s 4th industry-wide global web-based benchmarking survey on multi-mode microplate readers carried out in September 2013.
Scientific News
Diagnosing Cancer with Help from Bacteria
Engineered probiotics can detect tumors in the liver.
Imaging Test May Identify Biomarker of Alzheimer's Disease
Degeneration of the white matter of the brain may be an early marker of specific types of Alzheimer's disease (AD), including early-onset AD, according to results recently published.
New Chip Makes Testing For Antibiotic-Resistant Bacteria Faster, Easier
Researchers at the University of Toronto design diagnostic chip to reduce testing time from days to one hour, allowing doctors to pick the right antibiotic the first time.
New Way of Preventing Diabetes-Associated Blindness
Researchers have discovered a potential treatment for the most common cause of lose of vision in working age adults in the U.S.
Discovery of Pain-sensing Gene Key to New Relief Methods
A gene essential to the production of pain-sensing neurons in humans has been identified by an international team of researchers co-led by the University of Cambridge.
Genetic Markers for Detecting and Treating Ovarian Cancer
Custom bioinformatics algorithm identifies human mRNAs that distinguish ovarian cancer cells from normal cells and provide new therapeutic targets
What Drives Advanced Prostate Cancer?
Large international study finds 90% have anomaly that could influence treatment.
Slinky Lookalike “Hyperlens” Helps Us See Tiny Objects
The photonics advancement could improve early cancer detection, nanoelectronics manufacturing and scientists’ ability to observe single molecules.
Beyond Average
Researchers have created new platforms to genetically barcode tens of thousands of cells at a time allowing unprecedented detail to be uncovered when studying whole tissue samples.
FISHing for Insight
Improved imaging illuminates chromosomes in detail.
Business News
ARUP, Labceutics Partner
ARUP Laboratories and Labceutics are collaborating to provide test development and commercial diagnostics services to pharmaceutical companies.
Halozyme, Ventana Team Up for CDx Development
The two companies have announced an agreement to co-develop a diagnostic assay that twins with Halozyme's new investigational drug.
Biocartis and Fast-track Diagnostics Sign Strategic Collaboration
Both Companies aim to develop a range of multiplex tests on the Biocartis Idylla™ system each detecting a range of infectious disease pathogens.
Linkam and Cambridge IVF Collaborate to Develop New Protocols for Sperm Testing
The two companies are working together to develop new instrumentation and protocols to improve the reliability of sperm testing.
New Affordable Advanced NGS Cancer Test Launched by EKF subsidiary
Selah and GHS have partnered to produce an NGS technology, PrecisionPath, which will allow doctors to provide tailored cancer treatment based on a patients genes.
WHO Approves Ebola Assay
Xpert Ebola is now eligible for procurement to Ebola-affected countries
Horizon Discovery Appoints Mr Grahame Cook as a Non-Executive Director
Grahame brings over 20 years’ experience to Horizon.
Invitae Q1 Revenues Grow 10-Fold
The company have reported that they generated $1.2 million in first quarter revenues, a 10-fold increase from $118,000 in Q1 2014.
Congenica and UK Alliance Partner
This partnership aims to develop more accurate diagnostic tools that can lead to improved health outcomes for patients with genetic diseases, they announced recently.
Small Businesses Receive £1.25 Million SBRI Healthcare Funding
Latest award to support the development of 14 innovative new technologies in priority healthcare areas.

Events
63rd ASMS Conference on Mass S
31 May 2015
63rd ASMS Conference on Mass S ...
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2nd Promotional Review Committ
08 Jun 2015
2nd Promotional Review Committ ...
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German ePharma Day
11 Jun 2015
German ePharma Day ...
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Point of Care Diagnostics
11 Jun 2015
Point of Care Diagnostics ...
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ePosters
A Microwave/Microfluidics Integrated Label-Free Detection and Content Sensing System for Point-of-Care Applications
University of Waterloo

This poster presents a droplet-based microfluidic device integrated with a microwave wave sensor, which is also a heater, for simultaneous sensing and heating of individual nanoliter-sized droplets.
LOHA Comprehensive Assay for Single Nucleotide Polymorphism, Copy Number Variants and Loss of Heterozygosity Using SureSelect Target Enrichment
Agilent Technologies, Diagnostics and Genomics Group

Here we describe a comprehensive assay that enables researchers to identify SNP, INDEL, CNV, and LOH using SureSelect target enrichment. This design can be employed as a standalone entity or in concert with other bait designs for SNP and INDEL detection. We also describe methods for data analysis and visualization.
Alterations in serum thrombotic biomarker in patients with acute myocardial infarction
Dept of Biochemistry, Collage of Science, King Saud University, POB 2455, Riyadh 11451, Saudi Arabia

A combination of these biomarkers could serve as a useful biomarker tool to assess the prognosis of AMI. (This study was supported by National Plan for Science and Technology Program by King Saud University Project Number 08-BIO571-02).
Improved Small RNA Library Preparation Workflow for Next-Generation Sequencing
TriLink BioTechnologies

We describe an optimized small RNA NGS library prep workflow using chemically modified adapters which suppresses adapter dimers, allows for RNA inputs down to 1 ng and eliminates the need for a gel purification step, thus allowing full automation not previously possible.
Flexible automated platform for blood group genotyping on DNA microarrays
1 Établissement Français du Sang Rhône-Alpes, Lyon, France. 2 Établissement Français du Sang, La Plaine Saint Denis, France. 3 Établissement Français du Sang Alpes-Méd

The purpose of this project was to set up and validate a flexible robotic platform using 96-well DNA microarray for multiplex blood group genotyping.
Non-invasive Liquid Biopsy
1 Life Technologies AS, Ullerchausséen 52, 0379, Oslo, Norway; 2Department of Immunology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway; 3 Centre for Cancer Biomedicine, Univ

Paramagnetic Dynabeads® magnetic beads provide a versatile, automation friendly tool for fast sensitive and high throughput isolation that can be tailored to isolate specific circulating biomarkers such as cells, exosomes and nucleic acids.
Hand-held Automated Instrument for Microchip Electrophoresis with Amperometric Detection
Micrux Technologies

Microchips electrophoresis (ME) in combination with electrochemical detection (ED) can bring a new generation of point-of-care (POC) analysis systems in which would be integrated the main steps of an analytical process.
ENZYME COATED MAGNETIC NANOPARTICLES FOR USE IN CONTINUOUS FLOW MICROFLUIDIC DEVICES
Budapest University of Technology and Economics, Budapest, Hungary

A novel Lab-on-a-Chip platform is presented incorporates micro-sized magnetic reaction cells capable of anchoring protein-coated MNPs addressable and selectively. Such platform allows the design of highly flexible and "programmable" execution of multienzyme processes for biocatalytic or diagnostic purposes.
Pathogenesis and Clinical Presentation of Throat Candidiasis in Durrës area, Albania


In our study we have analyzed 1317 people, in the Microbiology Laboratory of DRSH, Durrës, Albania, suspected for C. albicans throat infections. Individuals we analysed were females and males, of different age groups, for the period of time between April 2012 and December 2013.


Electric Field-Induced Release and Measurement (EFIRM) can detect EGFR mutations directly from body fluids of lung cancer patients
School of Dentistry and Department of Pathology, University of California, Los Angeles, California. Institute of Clinical Medicine Department of Internal Medicine, and Department of Pathology, Na

In patients with NSCLC, Electric Field–Induced Release and Measurement (EFIRM) can detect EGFR mutations directly in saliva. This enables clinicians to adjust their therapeutic strategies in a timely fashion, consequently improving the clinical outcome of EGFR-targeted therapy.

Application Notes
Sample preparation with the AC Extraction Plate: extraction of urinary THC metabolites for LC-MSMS quantification
Tecan Group Ltd.

In many countries, routine workplace drug testing involves screening for the free THC-COOH metabolite obtained by hydrolyzing THC-COOH glucuronide. Tecan’s AC Extraction Plate with TICE technology enables a straightforward workflow that is reproducible and cost efficient. Liquid chromatography coupled with tandem mass spectrometry (LC-MSMS) provides an easy and cost-effective means for fast, sensitive and precise analysis of THC and its metabolites.
Automated sample preparation for the determination of testosterone in serum by LC-MSMS
Tecan Group Ltd.

For accurate, reproducible quantification of testosterone, a growing number of laboratories are shifting from immunoassay to liquid chromatography coupled with tandem mass spectrometry. This application note describes the preparation of serum samples for subsequent LC-MS analysis of testosterone, focusing on a streamlined workflow suitable for automation.
Validating the Expression Consistency of a Housekeeping Protein
Bio-Rad Laboratories

Housekeeping proteins (HKP) are typically used as loading controls because it is assumed that the HKP expression level remains consistent across samples. However, there is evidence that HKP expression levels change in many scenarios, including siRNA treatment, cell death, cell differentiation, etc.
A Method for Greater Reliability in Western Blot Loading Controls: Stain-Free Total Protein Quantitation
Bio-Rad Laboratories

Reliable assessment of changes in target protein levels by western blot requires measurement of both the target and loading control proteins in the linear dynamic range. Stain-free technology is a novel method introduced by Bio-Rad to visualize and quantify proteins in gels and blots.
General V3 Western Blotting Protocol
Bio-Rad Laboratories

Western blotting is a very useful and widely adopted lab technique, but the traditional procedure can be long and tedious. Researchers can assess only whether a blot image is captured at the end of the long procedure and the quality of western blot data is sometimes challenged due to poor loading controls.
Determining the Appropriate Sample Load When Using a Stain-Free V3 Western Workflow™
Bio-Rad Laboratories

Traditional western blot workflows require an appropriate sample load to detect both target proteins and loading control proteins. The discrepancy between these quantities often leads to oversaturated protein bands, forcing researchers to sometimes run two duplicate gels or titrate down the antibody concentration in order to get quantitative results.
Determining the Appropriate Film Exposure Time
Bio-Rad Laboratories

Film has a limited linear dynamic range for light detection and is often easily saturated by the chemiluminescent signals from the blot.
Determining the Appropriate Sample Load for Western Blots
Bio-Rad Laboratories

Reliable western blot data can be generated only when the proper sample amount of protein is used. Loading too much protein leads to signal saturation in western blots, yet too little produces weak signals.
Avoiding Housekeeping Protein Detection Saturation
Bio-Rad Laboratories

Reliable western blot data require detection of the target and loading control proteins in the linear dynamic range. Many published western blot images show saturated protein bands, indicating that they were not measured in the linear dynamic range. Quantitative analysis based on this type of data is not reliable.
Purification of Genomic DNA from Saliva Using Oragene® Discover Collection Kits and the Akonni TruTip® Extraction System on the Hamilton Microlab® STAR Liquid Handling Workstation
Hamilton

In the following studies, we have demonstrated the high precision of the automated TruTip extraction technology in processing genomic DNA from low-volume saliva samples and its advantage over competitors.
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