Corporate Banner
Satellite Banner
Molecular & Clinical Diagnostics
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Application of MALDI-TOF Mass Spectrometry in Clinical Virology

Published: Monday, December 16, 2013
Last Updated: Monday, December 16, 2013
Bookmark and Share
MS methods can be used currently for viral diagnosis but refinement of technology will be an important approach for the introduction of MALDI-TOF in routine viral diagnosis.

Abstract
MALDI-TOF mass spectrometry is a diagnostic tool of microbial identification and characterization based on the detection of the mass of molecules. In the majority of clinical laboratories, this technology is currently being used mainly for bacterial diagnosis, but several approaches in the field of virology have been investigated. The introduction of this technology in clinical virology will improve the diagnosis of infections produced by viruses but also the discovery of mutations and variants of these microorganisms as well as the detection of antiviral resistance. This review is focused on the main current applications of MALDI-TOF MS techniques in clinical virology showing the state of the art with respect to this exciting new technology.

The article is published online in The Open Virology Journal and is free to access.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 3,500+ scientific posters on ePosters
  • More than 5,000+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Plasma Biomarkers for Breast Cancer Diagnosis
Plasma lipidomics profiling identified lipid biomarkers in distinguishing early-stage breast cancer from benign lesions.
Wednesday, May 11, 2016
Metabolomics as a Diagnostic Tool in Gastroenterology
This review summarizes contributions that metabolomics has made in IBD and IBS and presents potential future directions within the field.
Thursday, December 12, 2013
Mass Spectrometry-Based Proteomics in Molecular Diagnostics: Discovery of Cancer Biomarkers Using Tissue Culture
Rapid development of MS-based proteomic techniques in the last decade that has immensely helped researchers in candidate biomarker discovery.
Monday, May 13, 2013
Simple Filter Microchip for Rapid Separation of Plasma and Viruses from Whole Blood
Scientists have developed a disposable, pump-free, size exclusion–based filter microchip that can be used for plasma and virus separation from unprocessed whole blood samples in resource-constrained settings.
Wednesday, October 17, 2012
Molecular Beacons in Diagnostics
Molecular beacons specific for different target sequences and labeled with differently colored fluorophores can be used together to simultaneously identify and quantitate multiple targets in the same assay tube.
Monday, May 28, 2012
Serious Bacterial Infection Biomarkers Uncovered using Transcriptomic Analysis
Novel biomarker combination improves the diagnosis of serious bacterial infections in Malawian children.
Monday, May 14, 2012
DNA Methylation Analysis of Bone Marrow Cells at Diagnosis of Acute Lymphoblastic Leukemia and at Remission
The aim of this study was to identify genes that display aberrant DNA methylation independently of cytogenetic ALL subtype for further mechanistic studies of ALL.
Monday, April 16, 2012
Differential Diagnosis in Idiopathic Granulomatous Mastitis and Tuberculous Mastitis
The purpose of this study is to develop a new algorithm for the differential diagnosis and treatment of IGM and TM.
Monday, April 16, 2012
Applications of Aptasensors in Clinical Diagnostics
This review attempts to list examples of the research progress of aptamers in biosensor platforms that have been published in recent years.
Monday, April 02, 2012
Use of DNA Microarray Analysis in Diagnosis of Bacterial and Fungal Endophthalmitis
Microarray analysis is complementary to routine cultures for identifying causative microorganisms and is likely to be a useful tool in patients with suspected endophthalmitis who require rapid diagnosis and early antibiotic treatment.
Wednesday, March 21, 2012
Comparison of Real-Time Quantitative PCR and Culture for the Diagnosis of Emerging Rickettsioses
Isolation of Rickettsia species from skin biopsies may be replaced by PCR. In this stidy, scientists evaluated culture sensitivity compared to PCR based on sampling delay and previous antibiotic treatment.
Tuesday, March 20, 2012
Genetic Variation Screening of TNNT2 Gene in a Cohort of Patients with Hypertrophic and Dilated Cardiomyopathy
This study analyzed TNNT2 exons in patients with HCM and DCM diagnosis to improve diagnostic and genetic consultancy in affected families.
Monday, March 05, 2012
Sensing Movement: Microsensors for Body Motion Measurement
Motion sensing is a critical sensing modality that plays an important role in medical practice. In this paper, state-of-the-art microscale motion sensing technologies that can be utilized for human body motion determination will be introduced.
Monday, March 05, 2012
Study on Pivot-Point Vibration of Molecular Bond-Rupture Events by Quartz Crystal Microbalance for Biomedical Diagnostics
Molecular bond-rupture scanning is an effective method for the measurement of the energy level necessary to break a bond and distinguishing specific and nonspecific binding of biological molecules.
Wednesday, February 22, 2012
Practical Tools to Implement Massive Parallel Pyrosequencing of PCR Products in Next Generation Molecular Diagnostics
Scientists from Ghent University outline different PCR amplification based strategies for the screening of a multitude of genes in a patient cohort.
Monday, October 17, 2011
Scientific News
Point of Care Diagnostics - A Cautious Revolution
Advances in molecular biology, coupled with the miniaturization and improved sensitivity of assays and devices in general, have enabled a new wave of point-of-care (POC) or “bedside” diagnostics.
ReadCoor Launched to Commercialize 3D Sequencing Tech
ReadCoor will leverage the Wyss Institute’s method for simultaneously sequencing and mapping RNAs within cells and tissues to advance development of diagnostics.
Crispr Toolbox Expanded By Protein
Researchers have shown a newly discovered CRISPR protein has two distinct RNA cutting activities.
Heart Arrhythmia Caused by Mosaic of Mutant Cells
Researchers have solved the genetic mystery of an infant suffering from heart arrhythmia.
Over Two-Thirds of Cervical Cancer Deaths Prevented
Cervical screening prevents 70% of cervical cancer deaths and if all eligible women regularly attended screening this would rise to 83%.
Detecting Bacterial Infections in Newborns
Researchers tested an alternative way to diagnose bacterial infections in infants—by analyzing RNA biosignatures from a small blood sample.
Case for Liquid Biopsies Builds in Advanced Lung Cancer
Study addresses unmet need for better, non-invasive tests called out in recent "Moonshot" blue ribbon panel report
Mechanisms of Parkinson’s Pathology
Defects that lead to cells’ failure to decommission faulty mitochondria cause nerve cells to die, triggering the symptoms of Parkinson’s disease.
Genetic Misdiagnoses of Heart Condition
Analysis found several genetic variations previously linked with a heart condition were harmless, leading to condition misdiagnosis.
Opening Door to Oesophageal Cancer Targeted Treatments
Scientists have discovered that oesophageal cancer can be classified into three different subtypes.
Skyscraper Banner

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,000+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!