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Improved Small RNA Library Preparation Workflow for Next-Generation Sequencing
Sabrina Shore, Jordana Henderson, Anton McCaffrey, Gerald Zon, Richard Hogrefe

We describe an optimized small RNA NGS library prep workflow using chemically modified adapters which suppresses adapter dimers, allows for RNA inputs down to 1 ng and eliminates the need for a gel purification step, thus allowing full automation not previously possible.

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Non-invasive Liquid Biopsy
Frauke Henjes1, Lise Aagaard1, Darren Ellis1, Hannah Lindstroem1, Morten Oksvold2,3, Axl Neurauter1, Ketil W. Pedersen1.

Paramagnetic Dynabeads® magnetic beads provide a versatile, automation friendly tool for fast sensitive and high throughput isolation that can be tailored to isolate specific circulating biomarkers such as cells, exosomes and nucleic acids.

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Flexible automated platform for blood group genotyping on DNA microarrays
S. Paris1, D. Rigal1, V. Barlet1, M. Verdier1, N. Coudurier2, P. Bailly3, J.-C. Brès1,4

The purpose of this project was to set up and validate a flexible robotic platform using 96-well DNA microarray for multiplex blood group genotyping.

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Hand-held Automated Instrument for Microchip Electrophoresis with Amperometric Detection
D.F. Pozo-Ayuso, A. Fernández-la-Villa, M. Castaño-Álvarez

Microchips electrophoresis (ME) in combination with electrochemical detection (ED) can bring a new generation of point-of-care (POC) analysis systems in which would be integrated the main steps of an analytical process.

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ENZYME COATED MAGNETIC NANOPARTICLES FOR USE IN CONTINUOUS FLOW MICROFLUIDIC DEVICES
Ferenc Ender, Diana Weiser, Andras Vitez, Laszlo Poppe

A novel Lab-on-a-Chip platform is presented incorporates micro-sized magnetic reaction cells capable of anchoring protein-coated MNPs addressable and selectively. Such platform allows the design of highly flexible and "programmable" execution of multienzyme processes for biocatalytic or diagnostic purposes.

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Pathogenesis and Clinical Presentation of Throat Candidiasis in Durrës area, Albania
PhD Cand. Anisa Liti, Prof. Dr. Margarita Hysko

In our study we have analyzed 1317 people, in the Microbiology Laboratory of DRSH, Durrës, Albania, suspected for C. albicans throat infections. Individuals we analysed were females and males, of different age groups, for the period of time between April 2012 and December 2013.

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Electric Field-Induced Release and Measurement (EFIRM) can detect EGFR mutations directly from body fluids of lung cancer patients
Fang Wei, Chien-Chung Lin,Szu-Chun Yang, Aron Joon, Ziding Feng, Gabriel Troche, Maruja E. Lira, David Chia, Mao Mao, Chung-Liang Ho, Wu-Chou Su, and David T. W. Wong

In patients with NSCLC, Electric Field–Induced Release and Measurement (EFIRM) can detect EGFR mutations directly in saliva. This enables clinicians to adjust their therapeutic strategies in a timely fashion, consequently improving the clinical outcome of EGFR-targeted therapy.

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Long-term on-chip storage and release of liquid reagents for diagnostic lab-on-a-chip applications
Daniel Czurratis*, Yvonne Beyl*, Sven Zinober*, Franz Lärmer*, Roland Zengerle**

We present a concept which enables on-chip storage of liquid reagents at room temperature and allows an easy implementation into pressure driven LoC devices.

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A multiplexed amplicon sequencing technology for FFPE and circulating, cell-free DNA
Laurie Kurihara, Catherine Couture, Julie Laliberte, Sukhinder Sandhu, Jonathan Irish, Tim Harkins and Vladimir Makarov

A novel amplicon approach allowing for hundreds of amplicons to be multiplexed in a single tube with a two workflow from sample to sequencer.

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Validation of Collection and Extraction Methods of Saliva for Use in Biomarker Research
Sarah E. Hurst and Brandon T. Hall

This poster investigates the collection and extraction methods of saliva for use in biomarker research.

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Scientific News
Genome Study Predicts DNA of the Whole of Iceland
Large genome databases are starting to reveal critical health information-even about people who have not contributed their DNA.
Blood Test Could Help Bowel Cancer Patients Avoid Drug Side-Effects
Manchester researchers have provided early evidence to suggest that a blood test could be used to identify bowel cancer patients that may benefit from more intensive chemotherapy.
Changes In A Blood-Based Molecular Pathway Identified In Alzheimer’s
Study identifies increased activation of the contact system in plasma of Alzheimer’s patients.
Bioinformatics Tool for Metagenome Analysis
‘GOTTCHA’ tool could aid ID of co-infections in medical samples.
Kidney Cancer Detected Early With Urine Test
Washington University School of Medicine researchers have developed a noninvasive method to screen for kidney cancer by measuring the presence of proteins in the urine.
New Test To Revolutionise Disease Detection In People, Crops And Stock
A single-drop DNA test invented by UQ scientists could revolutionise the detection of diseases in humans, livestock and crops.
DNA Sequencing Traces The Spread Of Drug-Resistant TB
Scientists have for the first time used DNA sequencing to trace the fatal spread of multidrug-resistant tuberculosis between patients in the UK.
Towards A Blood-Based Test For Diagnosing Alzheimer’s Disease
An effective blood test would be safe, affordable and easy to administer in large groups or in rural areas.
Tiny Optical Antennas: A Nano Revolution
Newly developed tiny optical antennas, which function like spotlights at the nanoscale, offer the potential to measure food safety, identify air pollutants and even quickly diagnose and treat deadly diseases, like cancer.
Blood-Based Genetic Biomarkers Identify Young Boys with Autism
Proof-of-principle method suggests much-earlier diagnoses could be done with clinic test.
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