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A Microwave/Microfluidics Integrated Label-Free Detection and Content Sensing System for Point-of-Care Applications
Gurkan Yesiloz, Muhammed S. Boybay, Carolyn L. Ren

This poster presents a droplet-based microfluidic device integrated with a microwave wave sensor, which is also a heater, for simultaneous sensing and heating of individual nanoliter-sized droplets.

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LOHA Comprehensive Assay for Single Nucleotide Polymorphism, Copy Number Variants and Loss of Heterozygosity Using SureSelect Target Enrichment
Kyeong Soo Jeong, Arjun Vadapalli, Ashutosh Ashutosh, Paula Costa, Brian Peter, Stephanie Fulmer-Smentek, Magnus Isaksson, Jayati Ghosh, Douglas Roberts, Holly Hogrefe

Here we describe a comprehensive assay that enables researchers to identify SNP, INDEL, CNV, and LOH using SureSelect target enrichment. This design can be employed as a standalone entity or in concert with other bait designs for SNP and INDEL detection. We also describe methods for data analysis and visualization.

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Alterations in serum thrombotic biomarker in patients with acute myocardial infarction
Abdullah S. Alhomida

A combination of these biomarkers could serve as a useful biomarker tool to assess the prognosis of AMI. (This study was supported by National Plan for Science and Technology Program by King Saud University Project Number 08-BIO571-02).

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Improved Small RNA Library Preparation Workflow for Next-Generation Sequencing
Sabrina Shore, Jordana Henderson, Anton McCaffrey, Gerald Zon, Richard Hogrefe

We describe an optimized small RNA NGS library prep workflow using chemically modified adapters which suppresses adapter dimers, allows for RNA inputs down to 1 ng and eliminates the need for a gel purification step, thus allowing full automation not previously possible.

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Non-invasive Liquid Biopsy
Frauke Henjes1, Lise Aagaard1, Darren Ellis1, Hannah Lindstroem1, Morten Oksvold2,3, Axl Neurauter1, Ketil W. Pedersen1.

Paramagnetic Dynabeads® magnetic beads provide a versatile, automation friendly tool for fast sensitive and high throughput isolation that can be tailored to isolate specific circulating biomarkers such as cells, exosomes and nucleic acids.

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Flexible automated platform for blood group genotyping on DNA microarrays
S. Paris1, D. Rigal1, V. Barlet1, M. Verdier1, N. Coudurier2, P. Bailly3, J.-C. Brès1,4

The purpose of this project was to set up and validate a flexible robotic platform using 96-well DNA microarray for multiplex blood group genotyping.

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ENZYME COATED MAGNETIC NANOPARTICLES FOR USE IN CONTINUOUS FLOW MICROFLUIDIC DEVICES
Ferenc Ender, Diana Weiser, Andras Vitez, Laszlo Poppe

A novel Lab-on-a-Chip platform is presented incorporates micro-sized magnetic reaction cells capable of anchoring protein-coated MNPs addressable and selectively. Such platform allows the design of highly flexible and "programmable" execution of multienzyme processes for biocatalytic or diagnostic purposes.

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Hand-held Automated Instrument for Microchip Electrophoresis with Amperometric Detection
D.F. Pozo-Ayuso, A. Fernández-la-Villa, M. Castaño-Álvarez

Microchips electrophoresis (ME) in combination with electrochemical detection (ED) can bring a new generation of point-of-care (POC) analysis systems in which would be integrated the main steps of an analytical process.

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Pathogenesis and Clinical Presentation of Throat Candidiasis in Durrës area, Albania
PhD Cand. Anisa Liti, Prof. Dr. Margarita Hysko

In our study we have analyzed 1317 people, in the Microbiology Laboratory of DRSH, Durrës, Albania, suspected for C. albicans throat infections. Individuals we analysed were females and males, of different age groups, for the period of time between April 2012 and December 2013.

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Electric Field-Induced Release and Measurement (EFIRM) can detect EGFR mutations directly from body fluids of lung cancer patients
Fang Wei, Chien-Chung Lin,Szu-Chun Yang, Aron Joon, Ziding Feng, Gabriel Troche, Maruja E. Lira, David Chia, Mao Mao, Chung-Liang Ho, Wu-Chou Su, and David T. W. Wong

In patients with NSCLC, Electric Field–Induced Release and Measurement (EFIRM) can detect EGFR mutations directly in saliva. This enables clinicians to adjust their therapeutic strategies in a timely fashion, consequently improving the clinical outcome of EGFR-targeted therapy.

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Scientific News
What Drives Advanced Prostate Cancer?
Large international study finds 90% have anomaly that could influence treatment.
Slinky Lookalike “Hyperlens” Helps Us See Tiny Objects
The photonics advancement could improve early cancer detection, nanoelectronics manufacturing and scientists’ ability to observe single molecules.
Study Looks at the Diagnostic Utility of Whole-Genome Sequencing
New research explores the potential of whole genome sequencing to revolutionize the diagnosis of genetic disorders in a clinical setting.
Genetic Signature Enables Early, Accurate Sepsis Diagnosis
Systemic inflammation after injuries or surgery can dramatically alter the activity of thousands of genes, but a new study shows that changes in just 11 of them are enough to detect the presence or absence of accompanying infection.
Map Diagnostics Developing Mass Spec Test for Down Syndrome
The company hopes that this new test will provide an accessible, affordable and rapid alternative to current screening methods.
New Method For Measuring The Concentration Of Medicines In The Blood
Researchers at EPFL have come up with a quick and portable new device for measuring the amount of medicinal drugs in blood.
New Test Could Identify Resistant Tuberculosis Faster
The time needed to genetically sequence the bacteria causing tuberculosis from patient samples has been reduced from weeks to days using a new technique developed by a UCL-led team.
New Blood Test For Fibromyalgia Moves A Step Closer
New research could lead to a blood test to diagnose fibromyalgia.
Smartphone Video Microscope Automates Detection Of Parasites In Blood
A mobile phone-based video microscope developed by a UC Berkeley-led team, is as good as conventional blood smears in detecting levels of the Loa loa parasitic worm.
Blood Markers Could Help Predict Outcome Of Infant Heart Surgery
New research suggests it may be possible to predict an infant’s progress following surgery for congenital heart disease by analysing a number of important small molecules in the blood.
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