G-Protein Coupled Receptors in Drug Discovery
20 Mar 2012 - 21 Mar 2012 - Berlin, Germany
Uncover new breakthroughs in GPCR structures and their impact on drug discovery; including structural determination details of the β2 adrenergic receptor–Gs protein complex and the human histamine H1 receptor complex with doxepin.
• Identify and understand the role of biased signalling and downstream signalling pathways activated by GPCRs and how to translate results into drug discovery programmes
• Explore novel approaches to understand allosterism in GPCRs; plus gain critical case study insights from Anchor Therapeutics and Addex Pharma into how they are overcoming the challenges in translating allosteric modulators into later phase drug development
• Discuss the application of novel screening methodologies for GPCRs – Uncover how label free screening can be applied for phenotypic primary cell analysis, innovative beta arrestin screening strategies and screening methodologies for the identification of allosteric modulators to aid drug discovery.
Please quote CQ2245TECH when booking your place. For more information, visit: http://www.informaglobalevents.com/CQ2245TECH