Protein Formulation Summit
10 Sep 2012 - 12 Sep 2012 - Boston, USA
Protein formulation development and how to develop an effective, marketable protein drug is a hugely important area for the pharmaceutical industry. However, there are a great many challenges currently preventing optimal formulation since protein molecules are so difficult to handle ‘at benchside’ and deliver to a patient ‘at bedside’. Theis plus many other areas need to be carefully dealt with, all the whilst being regulated to be safe for use in humans.
Selecting different formulation compositional elements; such as optimal pH, optimal buffers, optimal excipients, inferring structural chemical, physical and biological stability, ensuring minimal aggregation through effective predictive methods and undertaking novel delivery techniques through efficient early preformulation are just a sample of some the areas in need of focus. This event will look to provide insight into innovative techniques for these dilemmas and technologies being designed with which to predict, screen, test and accelerate formulation development towards license approval. In essence, there is currently no rational approach to develop a protein biotherapeutic, and this forum will seek to provide the information for formulation scientists to construct this.