Corporate Banner
Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>Events>This Event
  Events - October 2012


The importance of (Bio) Pharmaceutical properties in Successful Drug Design

04 Oct 2012 - 04 Oct 2012 - NHLI, Kensington, London



Bookmark and Share


The pressing challenge pharmaceutical scientists can often be faced with is dealing with drug development candidate molecules with sub-optimal drug delivery or pharmaceutical properties. This symposium brings together international experts from both the pharmaceutical industry and academia to discuss (bio)pharmaceutical properties and strategies to optimise pharmaceutical development and minimise development impact. Small molecule NCE topics include a formulation road map for oral delivery, assessment of CMC developability using material efficiency indices, preclinical assessment of amorphous solid dispersion and case studies of the use of in the development of compounds with poor aqueous solubility, and new insights into the solubilisation, supersaturation and precipitation behaviour of APIs. Biopharmaceutical topics will include microparticle-protein interactions and strategies for optimising delivery and PK of biopharmaceuticals.

Session 1 : Introduction and Chair - Dr Andrew Ratcliffe, Cellzome
10.00   Prof Graham Buckton, Pharmaterials
The form and the formulation - strategy for oral delivery
10.50Dr Andrey Peresypkin, Vertex, USA
Pre-Clinical assessment of CMC developability of drug candidates by using material efficiency indices as the integral part of the translational product development strategy
11.40Dr Mark Saunders, Kuecept
Preclinical assessment of amorphous solid dispersions: friend or foe?
12.30Lunch

Session 2 : Chair - Dr Mo Alavijeh, Pharmidex

13.40Dr David Lyon, Bends Research, USA 
Use of amorphous dispersions in the development of compounds with poor aqueous solubility: Case studies from discovery to commercial
14.30Mr Karl Box, Sirius
Small-scale solubility and dissolution assays; new insights into solubilisation, supersaturation and precipitation behaviour of APIs
15.20Tea
Session 3 : Chair - Dr Kate Brown, Imperial
15.40

Prof Ted Randolp, Centre for Pharmaceutical Biotechnology, USA
Microparticle-Protein interactions: Conformation, cavitation and immune response

16.30Dr Barry Moore, Xstalbio
Strategies for improving delivery, targeting and PK of Biopharmaceuticals




Further information
Scientific News
Liquid Biopsies: Utilization of Circulating Biomarkers for Minimally Invasive Diagnostics Development
Market Trends in Biofluid-based Liquid Biopsies: Deploying Circulating Biomarkers in the Clinic. Enal Razvi, Ph.D., Managing Director, Select Biosciences, Inc.
Lab-on-a-Chip Offers Promise for TB and Asthma Patients
A device to mix liquids using ultrasonics is the first and most difficult component in a miniaturized system for low-cost analysis of sputum from patients with pulmonary diseases such as tuberculosis and asthma.
Intracellular Microlasers Could Allow Precise Labeling of up to a Trillion Individual Cells
MGH investigators have induced structures incorporated within individual cells to produce laser light at wavelengths that differ based on the size, shape and composition of each microlaser, allowing precise labeling of individual cells.
Real-Time Imaging of Lung Lesions During Surgery
Targeted molecular agents cause lung adenocarcinomas to fluoresce during surgery, according to pilot report.
Watching a Tumour Grow in Real-Time
Researchers from the University of Freiburg have gained new insight into the phases of breast cancer growth.
Protein Related to Long Term Traumatic Brain Injury Complications Discovered
NIH-study shows protein found at higher levels in military members who have suffered multiple TBIs.
Childhood Cancer Cells Drain Immune System’s Batteries
Cancer cells in neuroblastoma contain a molecule that breaks down a key energy source for the body’s immune cells, leaving them too physically drained to fight the disease.
Urine Proteins Point to Early-Stage Pancreatic Cancer
A combination of three proteins found at high levels in urine can accurately detect early-stage pancreatic cancer, researchers at the BCI have shown.
Researcher Discovers Trigger of Deadly Melanoma
New research sheds light on the precise trigger that causes melanoma cancer cells to transform from non-invasive cells to invasive killer agents, pinpointing the precise place in the process where "traveling" cancer turns lethal.
New Vaccine For Chlamydia to Use Synthetic Biology
Prokarium Ltd, a biotechnology company developing transformational oral vaccines, have announced new funding from SynbiCITE, the UK’s Innovation and Knowledge Centre for Synthetic Biology.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FREE!