Corporate Banner
Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>Events>This Event
  Events - October 2012


The importance of (Bio) Pharmaceutical properties in Successful Drug Design

04 Oct 2012 - 04 Oct 2012 - NHLI, Kensington, London



Bookmark and Share


The pressing challenge pharmaceutical scientists can often be faced with is dealing with drug development candidate molecules with sub-optimal drug delivery or pharmaceutical properties. This symposium brings together international experts from both the pharmaceutical industry and academia to discuss (bio)pharmaceutical properties and strategies to optimise pharmaceutical development and minimise development impact. Small molecule NCE topics include a formulation road map for oral delivery, assessment of CMC developability using material efficiency indices, preclinical assessment of amorphous solid dispersion and case studies of the use of in the development of compounds with poor aqueous solubility, and new insights into the solubilisation, supersaturation and precipitation behaviour of APIs. Biopharmaceutical topics will include microparticle-protein interactions and strategies for optimising delivery and PK of biopharmaceuticals.

Session 1 : Introduction and Chair - Dr Andrew Ratcliffe, Cellzome
10.00   Prof Graham Buckton, Pharmaterials
The form and the formulation - strategy for oral delivery
10.50Dr Andrey Peresypkin, Vertex, USA
Pre-Clinical assessment of CMC developability of drug candidates by using material efficiency indices as the integral part of the translational product development strategy
11.40Dr Mark Saunders, Kuecept
Preclinical assessment of amorphous solid dispersions: friend or foe?
12.30Lunch

Session 2 : Chair - Dr Mo Alavijeh, Pharmidex

13.40Dr David Lyon, Bends Research, USA 
Use of amorphous dispersions in the development of compounds with poor aqueous solubility: Case studies from discovery to commercial
14.30Mr Karl Box, Sirius
Small-scale solubility and dissolution assays; new insights into solubilisation, supersaturation and precipitation behaviour of APIs
15.20Tea
Session 3 : Chair - Dr Kate Brown, Imperial
15.40

Prof Ted Randolp, Centre for Pharmaceutical Biotechnology, USA
Microparticle-Protein interactions: Conformation, cavitation and immune response

16.30Dr Barry Moore, Xstalbio
Strategies for improving delivery, targeting and PK of Biopharmaceuticals




Further information
Scientific News
Shedding Light on HIV Vaccine Design
Broadly speaking - Mathematical modelling of host-pathogen coevolution sheds light on HIV vaccine design.
AACC 2016 Sees Clinical Chemistry Labs Drive Precision Medicine Offerings
Biomarker assays to enable precision medicine and risk assessment, mass spec-based tests designed for use in clinical labs large and small, and liquid biopsy technology captured the spotlight at the AACC annual meeting.
Automated Patch Clamping Trends
Learn more about current practices, preferences and metrics in ion channel drug screening using APC technology.
Lab-on-a-Stick: Miniaturised Clinical Testing For Fast Detection Of Antibiotic Resistance
A portable power-free test for the rapid detection of bacterial resistance to antibiotics has been developed by academics at Loughborough University and the University of Reading.
Genetic Ancestry of Cultivated Strawberry Unravelled
UNH scientists constructed a linkage map of the seven chromosomes of the diploid Fragaria iinumae, which allows them to fill in a piece of the genetic puzzle about the eight sets of chromosomes of the cultivated strawberry.
Progress In Vaccination Against Vespid Venom
Researchers at the Helmholtz Zentrum München and the Technical University Munich have presented a method which facilitates a personalised procedure for wasp allergy sufferers.
New Drug Target for Inflammatory Disorders
Penn study finds enigmatic molecules maintain equilibrium between fighting infection and inflammatory havoc.
Breast Cancer Cells Found To Switch Molecular Characteristics
Spontaneous interconversion between HER2-positive and HER2-negative states could contribute to progression, treatment resistance in breast cancer.
Mechanisms of Calcium Blockers
Researchers describe how the fundamental mode of action of two distinct chemical classes of calcium channel blockers differs.
Some Breast Cancer Patients With Low Genetic Risk Could Skip Chemotherapy
Genetic test can help predict survival and guide treatment options.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,300+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,900+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!