Corporate Banner
Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>Events>This Event
  Events - December 2012


Tablet Formulation Development (2 day)

03 Dec 2012 - 04 Dec 2012 - London, UK



Bookmark and Share


This unique course introduces and integrates the key elements of tablet development with the principles of Quality by Design (QbD) with 2 days of theory plus an optional practical day in our development laboratory. It will include experimental, hands-on experience of formulation development using the Gamlen Tablet Press.

Topics include:

·    Applying Quality by Design at the development phase

·    Relating drug substance properties to desired formulation characteristics

·    Development formula and process - how these are linked

·    Identifying processes which will minimise development and manufacturing costs

·    Developing the Product Control Strategy - Critical Quality Attributes and Critical Process Parameters

·    Using novel science - PAT, NIR, Atomic Force Microscope, real time particle analysis

Proper integration of all of these elements is essential to achieve 'Quality by Design' because data from each phase is used to control the next step in the development process. By achieving proper integration based on sound scientific principles, many development and production problems can be avoided.


 

The course includes case studies of tablet formulation development and a detailed step by step analysis of all elements of the tablet manufacturing process. Hands on, practical studies will underpin the scientific learning in this participative course.


Who should attend?
The course is designed for people new to tablet development, and those requiring a refresher in the area. It will also benefit Process Development experts wishing to extend their understanding of why products processes can go wrong, and regulatory and quality personnel who need to understand the development process.

Course Programme:
Day 1 The Product Development Lifecycle
. Making sense of ICH Q8, 9 and 10—moving from theory to practice
. Designing formulations and processes to meet the Target Product Profile
. Formulation development—Formula and process selection
. Product Optimisation and the formulation cycle
. Developing Product Control Strategies at the formulation development phase
. Tablet Film Coating polymers
Day 2 Advance characterisation and development techniques
. Formulation mapping using X-ray and Raman spectroscopy
. AFM in formulation development
. Real time particle size analysis
. Dryer control using NIR
. Blend uniformity assessment using NIR and other techniques
. Compressibility comparison using the Gamlen Tablet Press
. Characterisation of tablet coats using THz spectroscopy
Day 3 Formulation development in practice (BOOK SEPARATELY) (HANDS ON. LIMITED TO 10 participants only)
. Material characterisation for product development
. Direct compression
. Wet granulation
. Drying
. Milling
. Compression
. Formulation evaluation and final selection
Wherever possible participants should bring practical problems and examples which can be reviewed on the course. The course will be highly participative and useful for people with or without formulation experience.

Course Speakers: Dr Michael Gamlen and Dr Dipankar Dey


Further information
Scientific News
Liquid Biopsies: Miracle Diagnostic or Next New Fad?
Thanks to the development of highly specific gene-amplification and sequencing technologies liquid biopsies access more biomarkers relevant to more cancers than ever before.
Flu Vaccine May Reduce Risk of Death For Type 2 Diabetes Patients
Researchers at Imperial College London have suggested that the vaccine may have substantial benefits for patients with long-term conditions.
Cancer Gene-Drug Combinations Ripe for Precision Medicine
The study aims to expand the number of cancer gene mutations that can be paired with a precision therapy.
Porphyrins as Catalysts in Scalable Organic Reactions
This review covers the most relevant scalable porphyrin-catalysed procedures, showing how these compounds represent broad applications in chemistry.
CDC Updates Zika Recommendations
CDC has issued updated Zika recommendations and guidance for healthcare providers with a focus on sexual transmission.
Exploiting Malaria’s Achilles’ Heel
Researchers have uncovered an Achilles' heel in malaria's anti-drug treatment arsenal that could lead to a disease cure.
Genome of 6000-Year-Old Barley Sequenced
Researchers have successfully sequenced the genome of Chalcolithic barley grains for the first time.
3D Models May Yield Ovarian Cancer Insights
Researchers are developing new tools to decipher ovarian cancer developments through a 3D printing technology.
Targeting BRAF Mutations in Thyroid Cancer
Treating metastatic thyroid cancer patients harboring a BRAF mutation with vemurafenib showed anti-tumor activity in a third of patients.
Plant Compounds Fight Together Against Colon Cancer
Research shows treating colon cancer cells with curcumin, then silymarin is more effective than treatment with each individually.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,300+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,800+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!