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Home>Events>This Event
  Events - December 2012


Development and Manufacture of Effervescent Tablets (1 day)

14 Dec 2012 - 14 Dec 2012 - Window Conference Venue, 13 Windsor Street, Islington, London, N1 8QG



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Course objectives
All PharmaTraining courses focus on two key objectives.  These are to provide  attendees with  knowledge—information, which will assist you in making better  judgements— and skills, which will allow you to apply the knowledge you have  received.  We guarantee to engage your interest and commitment on the course,  and we expect our training to improve your effectiveness.

About this course
Effervescent products present particular problems in manufacture, which result  from their special requirements and particular utility.  In this one day workshop  led by two leading experts, the issues surrounding the development and manufacture of effervescent products are explored in depth including practical sessions.
 
Background
· What are the advantages and disadvantages of  effervescent tablets?
· What are their particular requirements?
· Why do they present problems?
 
Course Speakers
Dr Michael Gamlen is Managing Director of Pharmaceutical Development  Services Ltd, a pharmaceutical consultancy based in Nottingham (UK).  Dr Gamlen has over 30 years experience of tablet development. Awarded a First Class Honours degree in Pharmacy, specialising in Pharmaceutical Engineering, he studied for a PhD at Nottingham University.   Michael  continually updates  the  content of his  courses with  the  latest guidance and  extracts  of  up-to-the minute  scientific  papers.   He  provides  a  substantial body of relevant literature to all course participants as well as copies of all notes and guidance used and a workbook.  He is a popular and highly respected
presenter.
 
Paul Butler is an extremely experienced trainer, tablet manufacturing expert and consultant.  During the past 20 years, he has been involved as a senior consultant  for many projects in the pharmaceutical industry throughout the UK, Ireland, Europe, Africa, the Middle and Far East, and Australia.  
 
He has been advising and training people in a broad range of manufacturing areas
for many years.  He focuses on providing small groups of interested people with
his extensive experience in a small groups, hands-on setting.   
The experts on tablets

Who should attend
The course is designed for people working in formulation, process
development or manufacturing with responsibility for the development,
validation and manufacture of effervescent products.  The content will
complement that of the Tablet Formulation and Tablet Process
Development courses which immediately precede it.
 
Course Programme
Try it!! The workshop...
Using a laboratory tablet machine and some simple equipment, we experiment with effervescence and develop some simple products.
 Theory
• Effervescence systems.  What are they and how to they achieve their objectives
• Uniformity – achieving and assessing uniformity in effervescent systems.
• Taste and taste masking
• ODTs
• Specific problems with effervescent products—mixing, lubrication, compression.
 
Practice. Effervescent products in Production.
• Engineering requirements for effervescent products
• Process Validation—challenges and pitfalls
• Scale up and Technology Transfer—mixing issues
• Routine manufacture
Bring your problems— don’t leave them at work!
There will be plenty of opportunity to discuss specific problems, in confidence if required.
 Additional Resources
Online access to comprehensive publications including all relevant guidance
will be provided as well as colour copies of all presentations and case
studies.


Further information
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Research was published in the Journal of the American Medical Association.
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Mathematical model shows more cases may be prevented and more lives saved when using one dose of cholera vaccine instead of recommended two doses.
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Expert independent review concludes that e-cigarettes have potential to help smokers quit.
NIH Launches Human RSV Study
Study aims to understand infection in healthy adults to aid development of RSV medicines, vaccines.
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For patients with an often-deadly form of leukemia, new research suggests that lingering cancer-related mutations – detected after initial treatment with chemotherapy – are associated with an increased risk of relapse and poor survival.
Flu Remedies Help Combat E. coli Bacteria
Physiologists from the University of Zurich have now discovered why the intestinal bacterium Escherichia coli (E. coli) multiplies heavily and has an inflammatory effect.
Marijuana Genome Unraveled
A study by Canadian researchers is providing a clearer picture of the evolutionary history and genetic organization of cannabis, a step that could have agricultural, medical and legal implications for this valuable crop.
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