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  Events - December 2012


Development and Manufacture of Effervescent Tablets (1 day)

14 Dec 2012 - 14 Dec 2012 - Window Conference Venue, 13 Windsor Street, Islington, London, N1 8QG



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Course objectives
All PharmaTraining courses focus on two key objectives.  These are to provide  attendees with  knowledge—information, which will assist you in making better  judgements— and skills, which will allow you to apply the knowledge you have  received.  We guarantee to engage your interest and commitment on the course,  and we expect our training to improve your effectiveness.

About this course
Effervescent products present particular problems in manufacture, which result  from their special requirements and particular utility.  In this one day workshop  led by two leading experts, the issues surrounding the development and manufacture of effervescent products are explored in depth including practical sessions.
 
Background
· What are the advantages and disadvantages of  effervescent tablets?
· What are their particular requirements?
· Why do they present problems?
 
Course Speakers
Dr Michael Gamlen is Managing Director of Pharmaceutical Development  Services Ltd, a pharmaceutical consultancy based in Nottingham (UK).  Dr Gamlen has over 30 years experience of tablet development. Awarded a First Class Honours degree in Pharmacy, specialising in Pharmaceutical Engineering, he studied for a PhD at Nottingham University.   Michael  continually updates  the  content of his  courses with  the  latest guidance and  extracts  of  up-to-the minute  scientific  papers.   He  provides  a  substantial body of relevant literature to all course participants as well as copies of all notes and guidance used and a workbook.  He is a popular and highly respected
presenter.
 
Paul Butler is an extremely experienced trainer, tablet manufacturing expert and consultant.  During the past 20 years, he has been involved as a senior consultant  for many projects in the pharmaceutical industry throughout the UK, Ireland, Europe, Africa, the Middle and Far East, and Australia.  
 
He has been advising and training people in a broad range of manufacturing areas
for many years.  He focuses on providing small groups of interested people with
his extensive experience in a small groups, hands-on setting.   
The experts on tablets

Who should attend
The course is designed for people working in formulation, process
development or manufacturing with responsibility for the development,
validation and manufacture of effervescent products.  The content will
complement that of the Tablet Formulation and Tablet Process
Development courses which immediately precede it.
 
Course Programme
Try it!! The workshop...
Using a laboratory tablet machine and some simple equipment, we experiment with effervescence and develop some simple products.
 Theory
• Effervescence systems.  What are they and how to they achieve their objectives
• Uniformity – achieving and assessing uniformity in effervescent systems.
• Taste and taste masking
• ODTs
• Specific problems with effervescent products—mixing, lubrication, compression.
 
Practice. Effervescent products in Production.
• Engineering requirements for effervescent products
• Process Validation—challenges and pitfalls
• Scale up and Technology Transfer—mixing issues
• Routine manufacture
Bring your problems— don’t leave them at work!
There will be plenty of opportunity to discuss specific problems, in confidence if required.
 Additional Resources
Online access to comprehensive publications including all relevant guidance
will be provided as well as colour copies of all presentations and case
studies.


Further information
Scientific News
Criminal Justice Alcohol Program Linked to Decreased Mortality
Institute has announced that in the criminal justice alcohol program deaths dropped by 4.2 percent over six years.
Head Injury Patients have Protein Clumps Associated with Alzheimer’s Disease
Scientists have revealed that protein clumps associated with Alzheimer's disease are also found in the brains of people who have had a head injury.
Exposure to Air Pollution 30 Years Ago Associated with Increased Risk of Death
Exposure to air pollution more than 30 years ago may still affect an individual's mortality risk today, according to new research from Imperial College London.
More Then 1 in 20 U.S. Children have Dizziness and Balance Problems
Researchers at NIH have found that girls have a higher prevalence of dizziness and balance problems compared to boys, 5.7 percent and 5.0 percent.
Biosensors on Demand
New strategy results in custom "designer proteins" for sensing a variety of molecules.
Low-Cost, Portable NQR Spectroscopy
A researcher at Case Western Reserve University is developing a low-cost, portable prototype designed to detect tainted medicines and food supplements that otherwise can make their way to consumers. The technology can authenticate good medicines and supplements.
Structure of Brain Plaques in Huntington's
Researchers at the University of Pittsburgh School of Medicine have shown that the core of the protein clumps found in the brains of people with Huntington's disease have a distinctive structure, a finding that could shed light on the molecular mechanisms underlying the neurodegenerative disorder.
Insights into the Function of the Main Class of Drug Targets
About thirty percent of all medical drugs such as beta-blockers or antidepressants interact with certain types of cell surface proteins called G protein coupled receptors.
Spero Therapeutics Announces $30 Million Series B Preferred Financing
Company has announced financing of $30 million to support development of novel therapies to treat gram-negative bacterial infections.
Unique Mechanism for a High-Risk Leukemia
Researchers uncovered the aberrant mechanism underlying a notoriously treatment-resistant acute lymphoblastic leukemia subtype; findings offer lessons for understanding all cancers.
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