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Home>Events>This Event
  Events - December 2012


Development and Manufacture of Effervescent Tablets (1 day)

14 Dec 2012 - 14 Dec 2012 - Window Conference Venue, 13 Windsor Street, Islington, London, N1 8QG



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Course objectives
All PharmaTraining courses focus on two key objectives.  These are to provide  attendees with  knowledge—information, which will assist you in making better  judgements— and skills, which will allow you to apply the knowledge you have  received.  We guarantee to engage your interest and commitment on the course,  and we expect our training to improve your effectiveness.

About this course
Effervescent products present particular problems in manufacture, which result  from their special requirements and particular utility.  In this one day workshop  led by two leading experts, the issues surrounding the development and manufacture of effervescent products are explored in depth including practical sessions.
 
Background
· What are the advantages and disadvantages of  effervescent tablets?
· What are their particular requirements?
· Why do they present problems?
 
Course Speakers
Dr Michael Gamlen is Managing Director of Pharmaceutical Development  Services Ltd, a pharmaceutical consultancy based in Nottingham (UK).  Dr Gamlen has over 30 years experience of tablet development. Awarded a First Class Honours degree in Pharmacy, specialising in Pharmaceutical Engineering, he studied for a PhD at Nottingham University.   Michael  continually updates  the  content of his  courses with  the  latest guidance and  extracts  of  up-to-the minute  scientific  papers.   He  provides  a  substantial body of relevant literature to all course participants as well as copies of all notes and guidance used and a workbook.  He is a popular and highly respected
presenter.
 
Paul Butler is an extremely experienced trainer, tablet manufacturing expert and consultant.  During the past 20 years, he has been involved as a senior consultant  for many projects in the pharmaceutical industry throughout the UK, Ireland, Europe, Africa, the Middle and Far East, and Australia.  
 
He has been advising and training people in a broad range of manufacturing areas
for many years.  He focuses on providing small groups of interested people with
his extensive experience in a small groups, hands-on setting.   
The experts on tablets

Who should attend
The course is designed for people working in formulation, process
development or manufacturing with responsibility for the development,
validation and manufacture of effervescent products.  The content will
complement that of the Tablet Formulation and Tablet Process
Development courses which immediately precede it.
 
Course Programme
Try it!! The workshop...
Using a laboratory tablet machine and some simple equipment, we experiment with effervescence and develop some simple products.
 Theory
• Effervescence systems.  What are they and how to they achieve their objectives
• Uniformity – achieving and assessing uniformity in effervescent systems.
• Taste and taste masking
• ODTs
• Specific problems with effervescent products—mixing, lubrication, compression.
 
Practice. Effervescent products in Production.
• Engineering requirements for effervescent products
• Process Validation—challenges and pitfalls
• Scale up and Technology Transfer—mixing issues
• Routine manufacture
Bring your problems— don’t leave them at work!
There will be plenty of opportunity to discuss specific problems, in confidence if required.
 Additional Resources
Online access to comprehensive publications including all relevant guidance
will be provided as well as colour copies of all presentations and case
studies.


Further information
Scientific News
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A new device developed at the University of Michigan could provide a non-invasive way to monitor the progress of an advanced cancer treatment.
Releasing Cancer Cells for Better Analysis
A new device developed at the University of Michigan could provide a non-invasive way to monitor the progress of an advanced cancer treatment.
Apricot Kernels Pose Risk of Cyanide Poisoning
Eating more than three small raw apricot kernels, or less than half of one large kernel, in a serving can exceed safe levels. Toddlers consuming even one small apricot kernel risk being over the safe level.
Cell Transplant Treats Parkinson’s in Mice
A University of Wisconsin—Madison neuroscientist has inserted a genetic switch into nerve cells so a patient can alter their activity by taking designer drugs that would not affect any other cell.
Understanding Female HIV Transmission
Glowing virus maps points of entry through entire female reproductive tract for first time.
Genetic Markers Influence Addiction
Differences in vulnerability to cocaine addiction and relapse linked to both inherited traits and epigenetics, U-M researchers find.
Lab-on-a-Chip for Detecting Glucose
By integrating microfluidic chips with fiber optic biosensors, researchers in China are creating ultrasensitive lab-on-a-chip devices to detect glucose levels.
A lncRNA Regulates Repair of DNA Breaks in Breast Cancer Cells
Findings give "new insight" into biology of tough-to-treat breast cancer.
COPD Linked to Increased Bacterial Invasion
Persistent inflammation in COPD may result from a defect in the immune system that allows airway bacteria to invade deeper into the lung.
Detection of HPV in First-Void Urine
Similar sensitivity of HPV test on first void urine sample compared to cervical smear.
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