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  Events - November 2013

Cell Based Assays

18 Nov 2013 - 19 Nov 2013 - London, UK

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SMi is proud to present their 6th Annual...

Cell Based Assays

Following on from our hugely successful Cell-Based Assays conference in 2012, this year's agenda will provide a global forum for senior level decision makers and those working within Cell-Based Assays to meet.

Highly accurate in-vitro practices are becoming absolutely vital as is looking at cost-effective assay development. Cell based assays now play an important role into the research pipeline, making a large percentage of total research time and is set to show considerable growth over the coming years.

There are currently 15 FDA approved kinase inhibitor drugs, but there currently remains a huge uncapped potential with these drugs as over 90% of the kinome is unknown. Novel assays have identified kinase targets, improved the function of kinase inhibitors and led to an acceleration in drug discovery with new inhibitor classes.

See at Cell Based Assays 2013 how HCA can be utilised in your pre-clinical toxicology procedures to give highly accurate data.


Hear the latest on Phenotypic screening; how target based screening is allowing for identification of small molecules

See how you can implement a primary cell assay plan through a case study of SARdriving assay

The latest in GPCR and other ion channel targeting pathways and how they are being used in the most recent drug discovery assays

Adopt accelerated primary cell screening systems such as those utilised by GSK


Mao Xiang Chen, Biological and Cellular targets, GlaxoSmithKline

Martha Brown, Senior Associate Director, Boehringer-Ingelheim

Xavier Leroy, Director, Actelion

Steve Ludbrook, Section Head, GlaxoSmithKline

Urs Luethi, Senior Lab Head Discovery, Actelion

Anthony Davies, Director, Trinity College Dublin

Tyrell Norris, Team Leader – Cellular Reagents & Assay Development, AstraZeneca

Amir Gander, Senior Knowledge Transfer Associate, University College London

**Book by 19th July 2013 and save £300**

**Book by 31st September 2013 and save £100**

Visit our website here:

Alternatively, contact Fateja Begum on +44 (0)20 7827 6184 or email:

Further information
Scientific News
High Throughput Mass Spectrometry-Based Screening Assay Trends
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Genetic Basis of Fatal Flu Side Effect Discovered
A group of people with fatal H1N1 flu died after their viral infections triggered a deadly hyperinflammatory disorder in susceptible individuals with gene mutations linked to the overactive immune response, according to a recent study.
New Tech Vastly Improves CRISPR/Cas9 Accuracy
A new CRISPR/Cas9 technology developed by scientists at UMass Medical School is precise enough to surgically edit DNA at nearly any genomic location, while avoiding potentially harmful off-target changes typically seen in standard CRISPR gene editing techniques.
The MaxSignal Colistin ELISA Test Kit from Bioo Scientific
Kit can help prevent the antibiotic apocalypse by keeping last resort drugs out of the food supply.
"Good" Mozzie Virus Might Hold Key to Fighting Human Disease
Australian scientists have discovered a new virus carried by one of the country’s most common pest mosquitoes.
Non-Disease Proteins Kill Brain Cells
Scientists at the forefront of cutting-edge research into neurodegenerative diseases such as Alzheimer’s and Parkinson’s have shown that the mere presence of protein aggregates may be as important as their form and identity in inducing cell death in brain tissue.
Closing the Loop on an HIV Escape Mechanism
Research team finds that protein motions regulate virus infectivity.
New Class of RNA Tumor Suppressors Identified
Two short, “housekeeping” RNA molecules block cancer growth by binding to an important cancer-associated protein called KRAS. More than a quarter of all human cancers are missing these RNAs.
Potential Treatment for Life-Threatening Viral Infections Revealed
The findings point to new therapies for Dengue, West Nile and Ebola.
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