" "
Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>Events>This Event
  Events - December 2013


Biological Interpretation of Next-Generation Sequencing Data

02 Dec 2013 - 06 Dec 2013 - EMBL-EBI,Hinxton, Cambridge, UK



Bookmark and Share


Overview

The course covers analysis of NGS data. Using ChIP-Seq and RNA-Seq datasets as an example, the course will provide ideas and practical advice for the interpretation of NGS data sets in a genomic context.

Topics will include: RNA-Seq and ChIP-Seq data handling, quality assessment and visualisation; region identification and differential expression; data integration and external databases (ENCODE); statistical analysis using R/bioconductor.

What will I learn?

Lectures will give insight into how biological knowledge can be generated from NGS data and illustrate different ways of analysing and integrating such data. Practicals will consist of computer exercises that will enable the participants to apply statistical methods to the analysis of NGS data under the guidance of the lecturers and teaching assistants.

Familiarity with the technology and biological use cases of NGS is required, as is prior experience with standard RNA-Seq and/or ChIP-Seq workflows. Knowledge of R/Bioconductor and the Unix/Linux operating system are also required.

Is it right for me?

This course is aimed at advanced PhD students and post-doctoral researchers who are already applying next generation sequencing (NGS) technologies and bioinformatics methods in their research.

The aim of this course is to familiarise the participants with advanced data analysis methodologies for the interpretation and integration of data derived from different NGS applications including RNA-seq, ChIP-seq, DNA-methylation sequencing, genome-wide association studies (GWAS) and DNA variant detection.



Further information
Scientific News
Breaking Cell Barriers with Retractable Protein Nanoneedles
Adapting a bacterial structure, institute researchers have developed protein actuators that can mechanically puncture cells.
Gene Signature could Lead to a New Way of Diagnosing Lyme Disease
Lyme disease patients had distinctive gene signatures that persisted for at least three weeks, even after they had taken the antibiotics.
Retractable Protein Nanoneedles
The ability to control the transfer of molecules through cellular membranes is an important function in synthetic biology; a new study from researchers at Harvard’s Wyss Institute for Biologically Inspired Engineering and Harvard Medical School (HMS) introduces a novel mechanical method for controlling release of molecules inside cells.
Leukemia’s Surroundings Key to its Growth
Researchers at The University of Texas at Austin have discovered that a type of cancer found primarily in children can grow only when signaled to do so by other nearby cells that are noncancerous.
Common Cell Transformed into Master Heart Cell
By genetically reprogramming the most common type of cell in mammalian connective tissue, researchers at the University of Wisconsin—Madison have generated master heart cells — primitive progenitors that form the developing heart.
‘Smelling’ Prostate Cancer
A research team from the University of Liverpool and the University of the West of England (UWE Bristol) has reached an important milestone towards creating a urine diagnostic test for prostate cancer that could mean that invasive diagnostic procedures that men currently undergo eventually become a thing of the past.
Genetic Mutation that Prevents Diabetes Complications
The most significant complications of diabetes include diabetic retinal disease, or retinopathy, and diabetic kidney disease, or nephropathy. Both involve damaged capillaries.
A Crystal Clear View of Biomolecules
Fundamental discovery triggers paradigm shift in crystallography.
Could the Food we Eat Affect Our Genes?
Almost all of our genes may be influenced by the food we eat, according to new research.
NIH Seeks Research Applications to Study Zika in Pregnancy, Developing Fetus
Institute has announced that the new effort seeks to understand virus effect on reproduction and child development.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,900+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,200+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!