Corporate Banner
Satellite Banner
Technology
Networks
Scientific Communities
 
Become a Member | Sign in
Home>Events>This Event
  Events - May 2014


47th Course of the International School of Crystallography

30 May 2014 - 08 Jun 2014 - Erice, Italy



Bookmark and Share


Diseases, from bacterial and viral infections to cancer to chronic maladies, are still among the greatest problems for mankind, in spite of tremendous progress in genetics, biology, and chemistry.  Approaches to developing new treatments have changed over time, and so have the methodologies used, in order to solve the varied, new, challenging problems that may happen on the path to drug discovery.  Together with ever-evolving experimental techniques, a variety of computational approaches have been applied at the various stages of the drug design process, and in the past two decades structure-based drug design has become one of the mainstream approaches.  This method can be used to target protein-ligand and protein-protein interactions and nowadays is applicable to all aspects of drug discovery, including lead identification, lead optimization, ADMET prediction, and drug repurposing. 

The purpose of the course is dual:

1) It will provide a review of the fundamentals and the application of crystallography to drug design, and an evaluation of the technology at the present state.

2) It will review the progress in this field and summarize the application and results to current fields of interest.  

In addition to lectures, there will be hands-on workshops providing training in using modern computer programs.

The topics that will be covered are:

- Targeting Resistance in Design of Anti AIDS Drugs

- Molecular Modeling and Drug Design

- Targeting Protein-Protein Interactions

- Drug Design Targeting Bromodomains

- Targeting GPCRs for Drug Design

- Targeting Influenza Virus Polymerase

- The Small Molecule Universe

- Molecular Obesity and Other Addictions in Drug Discovery

- Energetics of Protein-Ligand Interactions

- Docking Experiences and Expectations

- Structure of Human G-Protein Coupled Receptor

- Using ARP/WARP for Structure-Based Drug Design

- Antibody Technologies to Stabilize Targets for NCE Screening

- Drug Design Tales from AstraZeneca

- High Resolution Protein-Ligand Interactions by X-rays and Neutrons

- Virus Structure and Antiviral Drug Design

- Structure-Based Design of Drugs Against Diabetes

- Membrane Protein Structure

- Structural Bioinformatics

- Protein Aggregation and Drug Design

- Turning on Enzymes with Small Molecules



Further information
Scientific News
Point of Care Diagnostics - A Cautious Revolution
Advances in molecular biology, coupled with the miniaturization and improved sensitivity of assays and devices in general, have enabled a new wave of point-of-care (POC) or “bedside” diagnostics.
Mass Spec Technology Drives Innovation Across the Biopharma Workflow
With greater resolving power, analytical speed, and accuracy, new mass spectrometry technology and techniques are infiltrating the biopharmaceuticals workflow.
One Step Closer to Precision Medicine for Chronic Lung Disease Sufferers
A study led by University of North Carolina at Chapel Hill, and National Jewish Health, has provided evidence of links between SNPs and known COPD blood protein biomarkers.
ReadCoor Launched to Commercialize 3D Sequencing Tech
ReadCoor will leverage the Wyss Institute’s method for simultaneously sequencing and mapping RNAs within cells and tissues to advance development of diagnostics.
NCI Collaborates with Multiple Myeloma Research Foundation
NCI collaborates with MMRF to incorporate genomic and clinical data into NCI Genomic Data Commons database.
New Imaging Technique in Alzheimer’s Disease
Study confirms new imaging technique corresponds a higher degree of actual brain changes.
Designing Drugs with a Whole New Toolbox
Researchers develop methods to design small, targeted proteins with shapes not found in nature.
Antibiotic Resistance Can Occur Naturally in Soil Bacteria
Scientists have found natural anti-biotic resistant bacteria in soils with little to no human exposure.
Protein Studies Discover Molecular Secrets
Two protein studies have mapped proteins that reveal the secrets to recycling carbon and healing cells.
Insight into Eye Diseases
Scientists recreate zebrafish cell regeneration from retinal stem cells in mice.
Scroll Up
Scroll Down
Skyscraper Banner

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
3,500+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,000+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!