Corporate Banner
Satellite Banner
Food & Beverage Analysis
Scientific Community
Become a Member | Sign in
Home>News>This Article

Scientist Awarded $1.9 Million to Study Food Intake and Metabolism

Published: Monday, August 20, 2012
Last Updated: Monday, August 20, 2012
Bookmark and Share
The award from the NIH will allow scientists from the Florida campus of The Scripps Research Institute to study pathways that regulate how we coordinate the timing of our desire for food throughout the day.

These pathways play a key role in maintaining the body’s balance between how much we eat and our metabolism and energy expenditure.

Andrew Butler, an associate professor at Scripps Research, is the principal investigator for the new four-year study.

The research focuses on the melanocortin-3 receptor (MC3R, a g-protein coupled receptor) in the central nervous system. The MC3R is one component of the central nervous melanocortin system, which normally responds to signals of nutrient intake. The actions of the central nervous melanocortin system involving MC3Rs are central to the regulation of our metabolism. Attenuated activity of this system has been implicated in a range of metabolic diseases, including obesity and insulin resistance (a precursor to diabetes).

“One function of the melanocortin system is to prevent obesity in humans,” he said, “and this system is therefore considered an attractive target for developing drugs against obesity and eating disorders. Unfortunately, very little is known about the functions of melanocortin-3 receptors.”

Butler’s ongoing research suggests that MC3Rs help synchronize our circadian rhythms (24-hour day-night cycles) with food intake. MC3Rs are also linked to the regulation of glucose production and insulin action during cycles of fasting and feeding.  

“Our goal for this new study is two-fold,” Butler said. “We want to identify the MC3R signaling pathways involved in regulating behaviors that anticipate feeding, and we want to look at pathways responsible for maintaining metabolic homeostasis.”

Beyond forming a better understanding of the functions of MC3R in the central nervous system, Butler said, the ultimate point of the research is to develop new and innovative approaches to prevent and treat metabolic and circadian-rhythm disorders.

Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,800+ scientific posters on ePosters
  • More than 4,000+ scientific videos on LabTube
  • 35 community eNewsletters

Sign In

Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Revealing Molecular Secrets Behind the Health Benefits of Wine
Resveratrol has been much in the news as the component of grapes and red wine associated with reducing “bad cholesterol,” heart disease and some types of cancer.
Wednesday, April 30, 2014
Scientific News
The MaxSignal Colistin ELISA Test Kit from Bioo Scientific
Kit can help prevent the antibiotic apocalypse by keeping last resort drugs out of the food supply.
Kitchen Utensils Can Spread Bacteria Between Foods
In a recent study researchers found that produce that contained bacteria would contaminate other produce items through the continued use of knives or graters—the bacteria would latch on to the utensils commonly found in consumers' homes and spread to the next item.
GMO Food Animals Should be Judged by Product, Not Process
In a world with a burgeoning demand for meat, milk and eggs, regulatory policies around the use of biotechnologies in agriculture need to be based on the safety and attributes of those foods rather than on the methods used to produce them, says a UC Davis animal scientist.
Acetaldehyde and Formaldehyde Content in Foods
Korean researchers have determined the content of the toxic and carcinogenic aldehydes, acetaldehyde and formaldehyde, in a variety of food groups.
Increasing Vitamin D Supplementation
New study from ETH Zurich finds that elderly women should consume more vitamin D than previously recommended during the winter months.
IARC Monographs Evaluate Consumption of Red Meat and Processed Meat
Processed meat eaten daily increases the risk of colorectal cancer by 18%.
Nanoparticles in Foods Raise Safety Questions
Nanoparticles can make foods like jawbreaker candies brighter and creamier and keep them fresh longer. But researchers are still in the dark about what the tiny additives do once inside our bodies.
Arsenic Found in Many U.S. Red Wines
A new University of Washington study that tested 65 wines from America’s top four wine-producing states — California, Washington, New York and Oregon — found all but one have arsenic levels that exceed what’s allowed in drinking water.
Viruses Join Fight Against Harmful Bacteria
Engineered viruses could combat human disease and improve food safety.
Plastic for Dinner
Roughly a quarter of the fish sampled from fish markets in California and Indonesia contained man-made debris according to a study from the University of California, Davis, and Hasanuddin University in Indonesia.

SELECTBIO Market Reports
Go to LabTube
Go to eposters
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,800+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
4,000+ scientific videos