Corporate Banner
Satellite Banner
Food & Beverage Analysis
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

High Throughput Natural Product Discovery

Published: Monday, January 28, 2013
Last Updated: Sunday, January 27, 2013
Bookmark and Share
A technical article from Genevac details how its HT-24 centrifugal evaporation system can find and isolate novel flavour ingredients from nature.

Natural product derived discovery of novel flavour molecules is a highly complex process. Natural product sources yield complex extracts containing many components, which often do not lend themselves to processing and analysis.

Conventionally, many steps of fractionation and evaluation are necessary until a compound is obtained from natural sources at the purity required for structural analysis.

In the article a fractionation process using a Sepbox® Preparative HPLC - SPE system and a Genevac® HT-24 centrifugal evaporator is described.

The Sepbox enables two dimensional, preparative scale fractionation of natural products using high performance liquid chromatography - solid phase extraction (HPLC-SPE).

In sequential HPLC-SPE / HPLC-SPE steps individual components are isolated from complex mixtures. Each separation run produced 320 samples of approximately 45ml volume.

A Genevac HT-24 Evaporator was chosen to dry the samples because of its high sample capacity, unique technology that eliminates cross contamination due to sample bumping and automated monitoring of temperature and pressure to prevent sample degradation.

Able to evaporate 192 sample vials simultaneously the HT-24 took just two days to dry all the fractions ready for further liquid handling and testing.

Compact in design and offering a very high capacity for a wide range of sample formats including microplates, tubes, vials, fraction collector racks and Genevac’s hybrid HPLC blocks the HT-24 offers the versatility and productivity to assist chemists in high-throughput environments.

The high-throughput design of the HT-24 allows up to 96 shallow-well microplates to be dried down at the same time, while capacity for standard 16 x 100mm fraction collector tubes is an outstanding 576 tubes per run.

Benefiting from Genevac’s 20+ years of designing centrifugal evaporators the HT-24 is easy to use, reliable, robust and safe to both operator and sample integrity.

Further aiding productivity the HT-24 includes facility for rapid defrosting, and pull-out sample shelves for easy loading and unloading.


Further Information

Join For Free

Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 4,000+ scientific posters on ePosters
  • More than 5,300+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.


Scientific News
Bird Flu Confirmed in the Netherlands
An outbreak of H5 avian influenza was confirmed in the Flevoland province of the Netherlands.
Pasteurised Bacterium Reduces Obesity and Diabetes
Researchers have discovered that an intestinal bacterium provides a lasting effect on the intestinal barrier.
Failings in Conveying Risks of Undercooked Meat
A study has found that restaurants do not communicate the risks of eating undercooked meats.
Accelerating the Detection of Foodborne Bacterial Outbreaks
The speed of diagnosis of foodborne bacterial outbreaks could be improved by a new technique developed by researchers at the Georgia Institute of Technology.
Sweet Tooth Science - Chocolate Antioxidants
Researchers develop a faster and cheaper method to test for antioxidants in chocolate.
Food Additives Promote Inflammation, Colon Cancer
Dietary emulsifiers promoted colon cancer in a mouse model by altering gut microbes and increasing gut inflammation.
Detecting Food Contaminants with a Smartphone
Researchers aim to develop a novel food safety monitoring method using a smartphone.
Alarming Glyphosate Levels Found in Foods
Glyphosate has been found at alarming levels in a wide range of best-selling foods across the U.S.
Are Sweeteners as Natural as We Think?
New research study supports stevia’s naturality by identifying nine required molecules present in the dried stevia leaf.
Pre-Cut Salad May Encourage Growth of Salmonella
Study suggests damage to produce in bagged salads encourage the presence of Salmonella.
SELECTBIO

SELECTBIO Market Reports
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
4,000+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
5,300+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FOR FREE!