Corporate Banner
Satellite Banner
Food & Beverage Analysis
Scientific Community
 
Become a Member | Sign in
Home>News>This Article
  News
Return

Vanquish UHPLC sees Thermo Fisher Scientific Reimagine UHPLC

Published: Tuesday, July 15, 2014
Last Updated: Tuesday, July 15, 2014
Bookmark and Share
Thermo Fisher Scientific has unveiled a new high performance liquid chromatography system designed from the ground up to provide new levels of performance, productivity and usability when used as a standalone system or with the latest mass spectrometers.

The new Thermo Scientific Vanquish UHPLC looks different from standard UHPLC systems, and there are benefits to its clean design. The monolithic case contains an instrument that combines the ruggedness of an integrated system with the flexibility and serviceability of a modular system. Vanquish stands about 25 percent lower than comparable modular stacks for safety and convenience in the laboratory. 

“Rather than making incremental improvements to UHPLC, Thermo Fisher Scientific has designed this system from the ground up. The result is a system that combines advantages in separations performance, sample throughput, ease-of-use, reproducibility and method transfer efficiency,” said Fraser McLeod, vice president and general manager, HPLC, Thermo Fisher Scientific. 

Central to the Vanquish concept is the new family of Thermo Scientific Accucore Vanquish UHPLC columns, specially designed to optimize performance. The new columns feature 1.5 µm solid core particles utilizing Core Enhanced Technology to take full advantage of the Vanquish system’s 1500 bar (22,000 psi) maximum pump pressure and flow rate up to 5mL/min for ultra-short diffusion path lengths and highly efficient separations.

Other features add to the system’s performance, throughput and usability, including:

• SmartFlow pumping technology designed for highly reproducible retention times  and low baseline noise to enhance detection sensitivity;
• Temperature control capabilities, including direct heating and forced air temperature control modules in the column compartment, further enhancing separation efficiency and selectivity, as well as retention time reproducibility;
• An insulated autosampler compartment with new air-to-air cooling, which protects vials from water condensation, even in hot and humid environments;
• Gold-standard Thermo Scientific Dionex Chromeleon Chromatography Data System, familiar in laboratories around the world, which can calibrate the system automatically and unattended. eWorkflow and Intelligent Run Control automation are designed to enhance data quality and instrument efficiency Instant data reprocessing paired with Cobra Peak Detection and Smart Link can speed data review significantly compared to manual procedures. Chromeleon software supports chromatography and mass spectrometry functions simultaneously.
• Optional handheld tablet lets users conveniently monitor system status, check runs and make changes.

For high sample throughput applications, the optional Thermo Scientific Vanquish Charger is a fully integrated robotic module that provides unattended, environmentally controlled sample management and loading into the Vanquish UHPLC system. It accommodates up to nine sample racks, deep well plates or 20 shallow well plates. This includes a bar code reader with empty shelf detection and rack/well plate verification. Users can add samples at any time, even while the instrument is operating, to enable maximum throughput and usability. 

Hard carbon-coated ceramic injection valve and pump pistons are designed to deliver consistent, reproducible performance for 200,000 injections, further enhancing uptime by minimizing maintenance. 

The Vanquish Diode Array Detector is designed to generate high-confidence data over a wide linear range with high signal-to-noise performance, beyond the capabilities of variable wavelength detectors. Low-dispersion 10 mm and 60 mm flow cells provide high sensitivity levels and wide linearity for demanding applications. Fused-silica LightPipe flow cells are designed to exploit low baseline drift for reproducible quantitation. Customers can acquire up to 10 signal channels simultaneously, and a spectrum 3D field at 200 Hz. Sensitivity, linearity, and spectral resolution can be tailored to suit the application using four programmable optical slit widths from 1 nm to 8 nm.


Further Information
Access to this exclusive content is for Technology Networks Premium members only.

Join Technology Networks Premium for free access to:

  • Exclusive articles
  • Presentations from international conferences
  • Over 2,400+ scientific posters on ePosters
  • More than 3,700+ scientific videos on LabTube
  • 35 community eNewsletters


Sign In



Forgotten your details? Click Here
If you are not a member you can join here

*Please note: By logging into TechnologyNetworks.com you agree to accept the use of cookies. To find out more about the cookies we use and how to delete them, see our privacy policy.

Related Content

Thermo Fisher Q3 Revenues up 31 Percent
Thermo Fisher announced that revenues grew 31% to $4.17 billion for the third quarter ended September 27, 2014.
Thursday, October 23, 2014
Thermo Fisher, NRLs Team to Confirm Dioxins in Feed and Food
Thermo Fisher Scientific worked closely with national reference labs (NRLs) in the European Union to support the development of new regulation.
Monday, September 08, 2014
Reimagining UHPLC
To learn more about the new Vanquish UHPLC system from Thermo Fisher Scientific we spoke to Wulff Niedner, Director of HPLC Product Marketing.
Thursday, July 17, 2014
Thermo, USDA-ARS and Penn State to Collaborate on Food Safety Testing
Industry, academic and government partners to characterize and develop rapid genetic tests for toxic E. coli species
Wednesday, May 21, 2014
Thermo Reports 22% Revenue Rise in Q1 2014
Results include the addition of Life Technologies as of February 4, 2014, and exclude the previously announced related divestitures as of March 22, 2014.
Wednesday, April 23, 2014
Thermo Completes Life Tech Acquisition
The completion of the transaction follows the receipt of all required regulatory approvals.
Tuesday, February 04, 2014
Thermo Reports 6% Q4 Revenue Growth
Thermo Fisher Scientific Inc. reported its financial results for the fourth quarter and full year ended December 31, 2013.
Friday, January 31, 2014
Thermo Receives EC Clearance for Life Tech Acquisition
Thermo Fisher Scientific announced that it has received approval from the European Commission (EC) for its pending acquisition of Life Technologies Corporation.
Tuesday, November 26, 2013
Thermo Fisher Scientific Expands Access to Peanut Allergy Tests
The Thermo Scientific ImmunoCAP peanut component tests are now available through the co-marketing and distribution collaboration with Quest Diagnostics.
Wednesday, August 21, 2013
Thermo Fisher Scientific Establishes Pesticide Analysis Center of Excellence
The center helps users apply the latest technology and expertise to challenging pesticide analysis in food and environmental laboratories.
Thursday, August 15, 2013
Record Revenues for Thermo Fisher Scientific
Revenue for the quarter grew 6% to $3.26 billion in 2012, versus $3.09 billion in 2011.
Thursday, January 31, 2013
Denmark’s National Food Institute Adopts Thermo Scientific ICP-MS
iCAP Q ICP-MS system to speciate arsenic and measure nanoparticles in food.
Tuesday, December 18, 2012
Scientific News
Study Questions Presence in Blood of Heart-Healthy Molecules from Fish Oil Supplements
A new study from the Perelman School of Medicine at the University of Pennsylvania questions the relevance of fish oil-derived SPMs and their purported anti-inflammatory effects in humans.
How To Keep Your Rice Arsenic-Free
Researchers at Queen’s University Belfast have made a breakthrough in discovering how to lower worrying levels of arsenic in rice that is eaten all over the world.
Pesticide Found in 70 Percent of Massachusetts’ Honey Samples
New Harvard University study says that the pesticide commonly found in honey samples is implicated in Colony Collapse Disorder.
Printed "Smart Cap" Detects Spoiled Food
It might not be long before consumers can just hit “print” to create an electronic circuit or wireless sensor in the comfort of their homes.
Red Wine Antioxidant May Provide New Cancer Therapy Options
Resveratrol and quercetin, two polyphenols that have been widely studied for their health properties, may soon become the basis of an important new advance in cancer treatment,
New Research will Show How the Environment Could Change the Way We Eat
A new study funded by the Wellcome Trust will investigate how environmental changes over the next 20-30 years may impact the way we eat, in the UK and worldwide.
Blue LEDs Can be Used to Preserve Food
Blue light emitting diodes (LEDs) have strong antibacterial effect on major foodborne pathogens and can be used as a chemical-free food preservation method, a new study has found.
FDA Declares Trans Fatty Acids Unsafe for Consumption
TFAs are widely recognized as the most harmful fat with regard to causing cardiovascular disease (CVD).
Fat, Sugar Cause Bacterial Changes that may Relate to Loss of Cognitive Function
A study has indicated that both a high-fat and a high-sugar diet, compared to a normal diet, cause changes in gut bacteria that appear related to a significant loss of "cognitive flexibility," or the power to adapt and adjust to changing situations.
How Anthrax Spores Grow in Cultured Human Tissues
New findings to help predict risk and outcomes of anthrax attacks.
SELECTBIO

Skyscraper Banner
Go to LabTube
Go to eposters
 
Access to the latest scientific news
Exclusive articles
Upload and share your posters on ePosters
Latest presentations and webinars
View a library of 1,800+ scientific and medical posters
2,400+ scientific and medical posters
A library of 2,500+ scientific videos on LabTube
3,700+ scientific videos
Close
Premium CrownJOIN TECHNOLOGY NETWORKS PREMIUM FREE!